ES462245A1 - Un procedimiento para preparar un agente antimaligno deriva-do del staphylococcus epidermidis stf. - Google Patents
Un procedimiento para preparar un agente antimaligno deriva-do del staphylococcus epidermidis stf.Info
- Publication number
- ES462245A1 ES462245A1 ES462245A ES462245A ES462245A1 ES 462245 A1 ES462245 A1 ES 462245A1 ES 462245 A ES462245 A ES 462245A ES 462245 A ES462245 A ES 462245A ES 462245 A1 ES462245 A1 ES 462245A1
- Authority
- ES
- Spain
- Prior art keywords
- agent
- antimalignant
- fraction
- solution
- concentrating
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
- C12P1/04—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using bacteria
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/44—Staphylococcus
- C12R2001/45—Staphylococcus epidermidis
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Mycology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Biomedical Technology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Compounds Of Unknown Constitution (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Un procedimiento para preparar un agente antimaligno derivado del Staphylococcus epidermidis STF, que comprende cultivar Staphylococcus epidermidis STF (Depósito Bikoken nº 3706) en un medio de cultivo líquido que contiene componentes de carbono, componentes de nitrógeno y sales inorgánicas, separar la materia sólida de la solución de cultivo, concentrar la solución restante, lavar el precipitado así formado con agua volver a disolver el precipitado, fraccionar la solución en un número de fracciones por medios de separación, seleccionar una fracción que presenta actividad antimaligna, concentrar la fracción, purificar más la fracción y separar el ingrediente activo.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP10964876A JPS5334914A (en) | 1976-09-13 | 1976-09-13 | Antitumor agent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES462245A1 true ES462245A1 (es) | 1979-07-16 |
Family
ID=14515604
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES462245A Expired ES462245A1 (es) | 1976-09-13 | 1977-09-09 | Un procedimiento para preparar un agente antimaligno deriva-do del staphylococcus epidermidis stf. |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US4159321A (es) |
| JP (1) | JPS5334914A (es) |
| AR (1) | AR215143A1 (es) |
| AT (1) | AT349137B (es) |
| AU (1) | AU515706B2 (es) |
| BE (1) | BE858661A (es) |
| DE (1) | DE2741234C3 (es) |
| DK (1) | DK406977A (es) |
| ES (1) | ES462245A1 (es) |
| FI (1) | FI772677A (es) |
| FR (1) | FR2364033A1 (es) |
| GB (1) | GB1530846A (es) |
| HK (1) | HK69579A (es) |
| IL (1) | IL52893A (es) |
| MY (1) | MY8000102A (es) |
| NL (1) | NL7709987A (es) |
| NO (1) | NO773134L (es) |
| NZ (1) | NZ185160A (es) |
| PT (1) | PT67012B (es) |
| SE (1) | SE7710201L (es) |
| YU (1) | YU215077A (es) |
| ZA (1) | ZA775450B (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5632492A (en) * | 1979-08-28 | 1981-04-01 | Mitsui Toatsu Chem Inc | Antitumor active substance, its preparation and pharmaceutical |
| EP0157371A3 (de) * | 1984-04-04 | 1988-03-23 | Peters, Georg, Dr. med. | Arzneimittel mit immunmodulierender und die Proliferation von malignen Zellen hemmender Wirkung und Verfahren zu seiner Herstellung |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3366540A (en) * | 1962-08-03 | 1968-01-30 | Health Education Welfare Usa | Antibiotic anti-tumor agents and method of producing same |
| US3625833A (en) * | 1970-01-23 | 1971-12-07 | James J Schaffer | Process for producing antiviral substance from staphylococcus organisms |
-
1976
- 1976-09-13 JP JP10964876A patent/JPS5334914A/ja active Pending
-
1977
- 1977-09-05 IL IL52893A patent/IL52893A/xx unknown
- 1977-09-06 US US05/830,746 patent/US4159321A/en not_active Expired - Lifetime
- 1977-09-06 AU AU28577/77A patent/AU515706B2/en not_active Expired
- 1977-09-08 PT PT67012A patent/PT67012B/pt unknown
- 1977-09-09 ES ES462245A patent/ES462245A1/es not_active Expired
- 1977-09-09 YU YU02150/77A patent/YU215077A/xx unknown
- 1977-09-09 FI FI772677A patent/FI772677A/fi not_active Application Discontinuation
- 1977-09-12 NZ NZ185160A patent/NZ185160A/xx unknown
- 1977-09-12 NL NL7709987A patent/NL7709987A/xx not_active Application Discontinuation
- 1977-09-12 AR AR269163A patent/AR215143A1/es active
- 1977-09-12 AT AT653777A patent/AT349137B/de not_active IP Right Cessation
- 1977-09-12 NO NO773134A patent/NO773134L/no unknown
- 1977-09-12 SE SE7710201A patent/SE7710201L/xx not_active Application Discontinuation
- 1977-09-12 ZA ZA00775450A patent/ZA775450B/xx unknown
- 1977-09-13 BE BE180878A patent/BE858661A/xx unknown
- 1977-09-13 FR FR7727645A patent/FR2364033A1/fr not_active Withdrawn
- 1977-09-13 DE DE2741234A patent/DE2741234C3/de not_active Expired
- 1977-09-13 GB GB38218/77A patent/GB1530846A/en not_active Expired
- 1977-09-13 DK DK406977A patent/DK406977A/da not_active Application Discontinuation
-
1979
- 1979-09-27 HK HK695/79A patent/HK69579A/xx unknown
-
1980
- 1980-12-30 MY MY102/80A patent/MY8000102A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE2741234C3 (de) | 1980-03-20 |
| AR215143A1 (es) | 1979-09-14 |
| AU515706B2 (en) | 1981-04-16 |
| ZA775450B (en) | 1978-08-30 |
| NL7709987A (nl) | 1978-03-15 |
| MY8000102A (en) | 1980-12-31 |
| IL52893A0 (en) | 1977-11-30 |
| YU215077A (en) | 1982-06-30 |
| PT67012B (en) | 1979-02-13 |
| BE858661A (fr) | 1978-01-02 |
| AU2857777A (en) | 1979-03-15 |
| DK406977A (da) | 1978-03-14 |
| DE2741234B2 (de) | 1979-07-05 |
| NO773134L (no) | 1978-03-14 |
| IL52893A (en) | 1980-07-31 |
| SE7710201L (sv) | 1978-03-14 |
| DE2741234A1 (de) | 1978-03-16 |
| GB1530846A (en) | 1978-11-01 |
| FR2364033A1 (fr) | 1978-04-07 |
| PT67012A (en) | 1977-10-01 |
| NZ185160A (en) | 1979-08-31 |
| US4159321A (en) | 1979-06-26 |
| JPS5334914A (en) | 1978-03-31 |
| ATA653777A (de) | 1978-08-15 |
| AT349137B (de) | 1979-03-26 |
| FI772677A (fi) | 1978-03-14 |
| HK69579A (en) | 1979-10-05 |
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