ES457563A1 - Procedimiento para la obtencion de derivados de dipeptidos. - Google Patents
Procedimiento para la obtencion de derivados de dipeptidos.Info
- Publication number
- ES457563A1 ES457563A1 ES457563A ES457563A ES457563A1 ES 457563 A1 ES457563 A1 ES 457563A1 ES 457563 A ES457563 A ES 457563A ES 457563 A ES457563 A ES 457563A ES 457563 A1 ES457563 A1 ES 457563A1
- Authority
- ES
- Spain
- Prior art keywords
- activity
- carboxylic acid
- image
- compounds
- psychostimulants
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 108010016626 Dipeptides Proteins 0.000 title 1
- 150000001732 carboxylic acid derivatives Chemical class 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 230000000694 effects Effects 0.000 abstract 2
- XNSAINXGIQZQOO-UHFFFAOYSA-N L-pyroglutamyl-L-histidyl-L-proline amide Natural products NC(=O)C1CCCN1C(=O)C(NC(=O)C1NC(=O)CC1)CC1=CN=CN1 XNSAINXGIQZQOO-UHFFFAOYSA-N 0.000 abstract 1
- 102100032251 Pro-thyrotropin-releasing hormone Human genes 0.000 abstract 1
- 239000000627 Thyrotropin-Releasing Hormone Substances 0.000 abstract 1
- 101800004623 Thyrotropin-releasing hormone Proteins 0.000 abstract 1
- 239000000935 antidepressant agent Substances 0.000 abstract 1
- 229940005513 antidepressants Drugs 0.000 abstract 1
- 210000003169 central nervous system Anatomy 0.000 abstract 1
- 125000000487 histidyl group Chemical group [H]N([H])C(C(=O)O*)C([H])([H])C1=C([H])N([H])C([H])=N1 0.000 abstract 1
- 125000002883 imidazolyl group Chemical group 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- XNSAINXGIQZQOO-SRVKXCTJSA-N protirelin Chemical compound NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H]1NC(=O)CC1)CC1=CN=CN1 XNSAINXGIQZQOO-SRVKXCTJSA-N 0.000 abstract 1
- 239000003368 psychostimulant agent Substances 0.000 abstract 1
- 238000001228 spectrum Methods 0.000 abstract 1
- 230000004936 stimulating effect Effects 0.000 abstract 1
- 229940034199 thyrotropin-releasing hormone Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2615455A DE2615455C2 (de) | 1976-04-09 | 1976-04-09 | N-Acyl-L-histidyl-L-prolin (N-substituierte)-amide, Verfahren zu deren Herstellung und diese Verbindungen enthaltende pharmazeutische Zubereitungen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES457563A1 true ES457563A1 (es) | 1978-03-16 |
Family
ID=5974903
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES457563A Expired ES457563A1 (es) | 1976-04-09 | 1977-04-05 | Procedimiento para la obtencion de derivados de dipeptidos. |
Country Status (17)
| Country | Link |
|---|---|
| JP (1) | JPS52125166A (fr) |
| AT (1) | AT352921B (fr) |
| AU (1) | AU2322677A (fr) |
| BE (1) | BE853444A (fr) |
| CA (1) | CA1088520A (fr) |
| CH (1) | CH632737A5 (fr) |
| DE (1) | DE2615455C2 (fr) |
| DK (1) | DK148902C (fr) |
| ES (1) | ES457563A1 (fr) |
| FR (1) | FR2347338A1 (fr) |
| GB (1) | GB1564078A (fr) |
| IE (1) | IE44485B1 (fr) |
| NL (1) | NL7703789A (fr) |
| PT (1) | PT66283B (fr) |
| SE (1) | SE427835B (fr) |
| YU (1) | YU85977A (fr) |
| ZA (1) | ZA771097B (fr) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE58849B1 (en) * | 1984-12-18 | 1993-11-17 | Gruenenthal Chemie | Use of dipeptide derivatives for the manufacture of medicaments for the treatment of patients with amyotrophic lateral sclerosis |
| DE3502041A1 (de) | 1985-01-23 | 1986-07-24 | Grünenthal GmbH, 5190 Stolberg | Verwendung von dipeptidderivaten zur behandlung posttraumatischer nervenschaeden |
| JPS63316724A (ja) * | 1987-06-19 | 1988-12-26 | Nippon Shinyaku Co Ltd | 抗けいれん剤 |
| US5151497A (en) * | 1989-02-21 | 1992-09-29 | Japan Tobacco Inc. | Histidyl peptide derivatives |
| US6039956A (en) * | 1994-09-12 | 2000-03-21 | Pennsylvania, Trustees Of The University Of, The | Corticotropin release inhibiting factor and methods of using same for treating behavioral symptoms in an anxiety disorder |
| EP0781140A4 (fr) * | 1994-09-12 | 1999-11-03 | Univ Pennsylvania | Facteur inhibiteur de liberation de la corticotropine et procedes d'utilisation |
-
1976
- 1976-04-09 DE DE2615455A patent/DE2615455C2/de not_active Expired
-
1977
- 1977-02-21 AT AT113977A patent/AT352921B/de not_active IP Right Cessation
- 1977-02-23 ZA ZA00771097A patent/ZA771097B/xx unknown
- 1977-03-09 PT PT66283A patent/PT66283B/pt unknown
- 1977-03-15 AU AU23226/77A patent/AU2322677A/en not_active Expired
- 1977-03-15 GB GB10831/77A patent/GB1564078A/en not_active Expired
- 1977-03-16 CA CA274,078A patent/CA1088520A/fr not_active Expired
- 1977-03-21 IE IE593/77A patent/IE44485B1/en unknown
- 1977-03-31 YU YU00859/77A patent/YU85977A/xx unknown
- 1977-04-05 ES ES457563A patent/ES457563A1/es not_active Expired
- 1977-04-06 CH CH437277A patent/CH632737A5/de not_active IP Right Cessation
- 1977-04-06 SE SE7704088A patent/SE427835B/xx not_active IP Right Cessation
- 1977-04-06 NL NL7703789A patent/NL7703789A/xx not_active Application Discontinuation
- 1977-04-06 DK DK157077A patent/DK148902C/da not_active IP Right Cessation
- 1977-04-08 BE BE176590A patent/BE853444A/fr not_active IP Right Cessation
- 1977-04-08 JP JP3962977A patent/JPS52125166A/ja active Granted
- 1977-04-08 FR FR7710825A patent/FR2347338A1/fr active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| AU2322677A (en) | 1978-09-21 |
| NL7703789A (nl) | 1977-10-11 |
| ATA113977A (de) | 1979-03-15 |
| DK148902B (da) | 1985-11-11 |
| SE427835B (sv) | 1983-05-09 |
| FR2347338B1 (fr) | 1980-07-11 |
| IE44485B1 (en) | 1981-12-16 |
| YU85977A (en) | 1982-10-31 |
| CA1088520A (fr) | 1980-10-28 |
| PT66283B (de) | 1978-08-09 |
| DE2615455C2 (de) | 1985-06-20 |
| GB1564078A (en) | 1980-04-02 |
| PT66283A (de) | 1977-04-01 |
| DE2615455A1 (de) | 1977-10-20 |
| DK157077A (da) | 1977-10-10 |
| BE853444A (fr) | 1977-08-01 |
| FR2347338A1 (fr) | 1977-11-04 |
| JPS6110479B2 (fr) | 1986-03-29 |
| AT352921B (de) | 1979-10-10 |
| CH632737A5 (en) | 1982-10-29 |
| IE44485L (en) | 1977-10-09 |
| SE7704088L (sv) | 1977-10-10 |
| ZA771097B (en) | 1978-01-25 |
| DK148902C (da) | 1986-06-09 |
| JPS52125166A (en) | 1977-10-20 |
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| JPS51133271A (en) | Process for preparing heterocyclic compounds |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19990405 |