ES8302633A1 - Procedimiento para eliminar el grupo n-formilo de peptidos n-formilo de peptidos n-formilados o de esteres de peptidos n-formilados. - Google Patents
Procedimiento para eliminar el grupo n-formilo de peptidos n-formilo de peptidos n-formilados o de esteres de peptidos n-formilados.Info
- Publication number
- ES8302633A1 ES8302633A1 ES511760A ES511760A ES8302633A1 ES 8302633 A1 ES8302633 A1 ES 8302633A1 ES 511760 A ES511760 A ES 511760A ES 511760 A ES511760 A ES 511760A ES 8302633 A1 ES8302633 A1 ES 8302633A1
- Authority
- ES
- Spain
- Prior art keywords
- formyl
- esters
- removal
- peptides
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/12—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by hydrolysis, i.e. solvolysis in general
- C07K1/124—Hydrazinolysis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06104—Dipeptides with the first amino acid being acidic
- C07K5/06113—Asp- or Asn-amino acid
- C07K5/06121—Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
- C07K5/0613—Aspartame
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
PROCEDIMIENTO PARA LA ELIMINACION DEL GRUPO N-FORMILO DE PEPTIDOS N-FORMILADOS O DE ESTERES DE PEPTIDOS N-FORMILADOS. CONSISTE EN LA REACCION DE LOS PEPTIDOS N-FORMILADOS O DE SUS ESTERES CON HIDRACINA O CON HIDRACINA SUSTITUIDAS DE FORMULA RCONHNH , EN LA QUE R PUEDE SER UNO DE VARIOS TIPOS DE RADICALES, EN PROPORCION DE 1 A 5 MOLES POR MOL DE PEPTIDO, EN UN DISOLVENTE INERTE, A PH ENTRE 1 Y 3,5, A TEMPERATURAS COMPRENDIDAS ENTRE 20<025>C Y 150<025>C. ESTOS COMPUESTOS TIENEN APLICACIONES COMO SUSTANCIAS EDULCORANTES.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT21674/81A IT1194795B (it) | 1981-05-13 | 1981-05-13 | Procedimento per la eliminazione del gruppo n-formile da peptidi n-formilati e da esteri di peptidi n-formilati |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES511760A0 ES511760A0 (es) | 1983-02-01 |
| ES8302633A1 true ES8302633A1 (es) | 1983-02-01 |
Family
ID=11185195
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES511760A Expired ES8302633A1 (es) | 1981-05-13 | 1982-04-28 | Procedimiento para eliminar el grupo n-formilo de peptidos n-formilo de peptidos n-formilados o de esteres de peptidos n-formilados. |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US4434097A (es) |
| JP (1) | JPS5810546A (es) |
| KR (1) | KR840001342B1 (es) |
| AT (1) | ATA183082A (es) |
| AU (1) | AU537275B2 (es) |
| BE (1) | BE893074A (es) |
| CA (1) | CA1244406A (es) |
| CH (1) | CH648566A5 (es) |
| DE (1) | DE3216512C2 (es) |
| DK (1) | DK208082A (es) |
| ES (1) | ES8302633A1 (es) |
| FI (1) | FI821412L (es) |
| FR (1) | FR2505829B1 (es) |
| GB (1) | GB2098220B (es) |
| GR (1) | GR75497B (es) |
| IT (1) | IT1194795B (es) |
| NL (1) | NL8201821A (es) |
| NO (1) | NO821585L (es) |
| NZ (1) | NZ200583A (es) |
| PT (1) | PT74892B (es) |
| SE (1) | SE8202787L (es) |
| YU (1) | YU93882A (es) |
| ZA (1) | ZA823232B (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4555362A (en) * | 1983-06-20 | 1985-11-26 | G. D. Searle & Co. | Method and intermediates for producing α-L-aspartyl-L-phenylalanine |
| IT1190395B (it) * | 1985-09-30 | 1988-02-16 | Lark Spa | Procedimento per la rimozione del gruppo formile da un estere di n-formil peptide o di n-formil amminoacido |
| ATE487486T1 (de) * | 2002-05-24 | 2010-11-15 | Medtronic Inc | Polypeptid-spaltungsprozess |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1543610A1 (de) * | 1966-08-27 | 1969-07-31 | Hoechst Ag | Verfahren zur Herstellung von Aminosaeuren und Peptiden und deren Derivaten |
| US3933781A (en) * | 1973-11-05 | 1976-01-20 | Monsanto Company | Process for the preparation of α-L-aspartyl-L-phenylalanine alkyl esters |
| JPS5823380B2 (ja) * | 1974-12-05 | 1983-05-14 | 味の素株式会社 | ホルミルキノ ダツリホウ |
| JPS5223001A (en) * | 1975-08-14 | 1977-02-21 | Ajinomoto Co Inc | Process for elimination of formyl group |
-
1981
- 1981-05-13 IT IT21674/81A patent/IT1194795B/it active
-
1982
- 1982-04-23 FI FI821412A patent/FI821412L/fi not_active Application Discontinuation
- 1982-04-26 US US06/372,216 patent/US4434097A/en not_active Expired - Fee Related
- 1982-04-28 ES ES511760A patent/ES8302633A1/es not_active Expired
- 1982-04-29 YU YU00938/82A patent/YU93882A/xx unknown
- 1982-04-30 CA CA000402109A patent/CA1244406A/en not_active Expired
- 1982-04-30 CH CH2642/82A patent/CH648566A5/it not_active IP Right Cessation
- 1982-05-03 NL NL8201821A patent/NL8201821A/nl not_active Application Discontinuation
- 1982-05-03 DE DE3216512A patent/DE3216512C2/de not_active Expired
- 1982-05-04 SE SE8202787A patent/SE8202787L/ not_active Application Discontinuation
- 1982-05-05 BE BE2/59692A patent/BE893074A/fr not_active IP Right Cessation
- 1982-05-07 GB GB8213232A patent/GB2098220B/en not_active Expired
- 1982-05-10 AT AT0183082A patent/ATA183082A/de not_active Application Discontinuation
- 1982-05-10 DK DK208082A patent/DK208082A/da unknown
- 1982-05-11 JP JP57079805A patent/JPS5810546A/ja active Granted
- 1982-05-11 ZA ZA823232A patent/ZA823232B/xx unknown
- 1982-05-11 NZ NZ200583A patent/NZ200583A/en unknown
- 1982-05-12 NO NO821585A patent/NO821585L/no unknown
- 1982-05-12 PT PT74892A patent/PT74892B/pt unknown
- 1982-05-12 AU AU83612/82A patent/AU537275B2/en not_active Ceased
- 1982-05-13 GR GR68142A patent/GR75497B/el unknown
- 1982-05-13 KR KR8202080A patent/KR840001342B1/ko not_active IP Right Cessation
- 1982-05-13 FR FR8208355A patent/FR2505829B1/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| FI821412A0 (fi) | 1982-04-23 |
| FI821412L (fi) | 1982-11-14 |
| DE3216512A1 (de) | 1982-12-23 |
| NO821585L (no) | 1982-11-15 |
| YU93882A (en) | 1985-08-31 |
| GB2098220B (en) | 1984-08-15 |
| ATA183082A (de) | 1989-04-15 |
| PT74892A (en) | 1982-06-01 |
| KR830010053A (ko) | 1983-12-24 |
| SE8202787L (sv) | 1982-11-14 |
| IT1194795B (it) | 1988-09-28 |
| CH648566A5 (it) | 1985-03-29 |
| GR75497B (es) | 1984-07-24 |
| PT74892B (en) | 1984-08-02 |
| NL8201821A (nl) | 1982-12-01 |
| US4434097A (en) | 1984-02-28 |
| DE3216512C2 (de) | 1986-09-11 |
| CA1244406A (en) | 1988-11-08 |
| BE893074A (fr) | 1982-08-30 |
| IT8121674A1 (it) | 1982-11-13 |
| KR840001342B1 (ko) | 1984-09-19 |
| JPS5810546A (ja) | 1983-01-21 |
| AU8361282A (en) | 1982-11-18 |
| JPS616080B2 (es) | 1986-02-24 |
| ES511760A0 (es) | 1983-02-01 |
| ZA823232B (en) | 1983-03-30 |
| FR2505829B1 (fr) | 1985-10-25 |
| IT8121674A0 (it) | 1981-05-13 |
| DK208082A (da) | 1982-11-14 |
| AU537275B2 (en) | 1984-06-14 |
| FR2505829A1 (fr) | 1982-11-19 |
| GB2098220A (en) | 1982-11-17 |
| NZ200583A (en) | 1984-12-14 |
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