ES456370A1 - Procedimiento para preparar aril-3-oxazolidinonas-2. - Google Patents

Procedimiento para preparar aril-3-oxazolidinonas-2.

Info

Publication number
ES456370A1
ES456370A1 ES456370A ES456370A ES456370A1 ES 456370 A1 ES456370 A1 ES 456370A1 ES 456370 A ES456370 A ES 456370A ES 456370 A ES456370 A ES 456370A ES 456370 A1 ES456370 A1 ES 456370A1
Authority
ES
Spain
Prior art keywords
methyl
hydrogen
fluoro
nitro
carbon atoms
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES456370A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Delalande SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR7605751A external-priority patent/FR2342729A1/fr
Application filed by Delalande SA filed Critical Delalande SA
Publication of ES456370A1 publication Critical patent/ES456370A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • C07D263/24—Oxygen atoms attached in position 2 with hydrocarbon radicals, substituted by oxygen atoms, attached to other ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychiatry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Procedimiento para preparar nuevas aril-3-oxazolidinonas-2, útiles sobre todo en el campo sicotrópico. Los compuestos según la invención responden más precisamente a la siguiente fórmula (I): **(Fórmula)** en la que R1 representa: - o bien átomo de hidrógeno, en cuyo caso R puede ser: un radical p-nitro, p-ciano, p-aldehido ó p-acetilo; un grupo m-etilo, m-nitro ó m-bromo; o dos grupos metilo situados en posición metal.
ES456370A 1976-03-01 1977-02-26 Procedimiento para preparar aril-3-oxazolidinonas-2. Expired ES456370A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR7605751A FR2342729A1 (fr) 1976-03-01 1976-03-01 Nouveaux derives de la carbamoyloxymethyl-5 oxazolidinone-2, leur procede de preparation et leur application en therapeutique
FR7619578A FR2356422A1 (fr) 1976-03-01 1976-06-28 Nouveaux hydroxymethyl-5 oxazolidinone-2, leur procede de preparation et leur application en therapeutique

Publications (1)

Publication Number Publication Date
ES456370A1 true ES456370A1 (es) 1978-01-16

Family

ID=26219328

Family Applications (1)

Application Number Title Priority Date Filing Date
ES456370A Expired ES456370A1 (es) 1976-03-01 1977-02-26 Procedimiento para preparar aril-3-oxazolidinonas-2.

Country Status (16)

Country Link
US (1) US4150029A (es)
JP (1) JPS6040428B2 (es)
AU (1) AU509376B2 (es)
BE (1) BE851893A (es)
CA (1) CA1106380A (es)
CH (2) CH618975A5 (es)
DE (1) DE2708236A1 (es)
ES (1) ES456370A1 (es)
FR (1) FR2356422A1 (es)
GB (1) GB1546741A (es)
GR (1) GR60803B (es)
IT (1) IT1071584B (es)
LU (1) LU76848A1 (es)
MX (1) MX4652E (es)
NL (1) NL7702148A (es)
SE (1) SE435928B (es)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LU80081A1 (fr) * 1977-08-26 1979-05-15 Delalande Sa Nouvelles hydroxymethyl-5 oxazolidinones-2,leur procede de preparation et leur application therapeutique
US4348393A (en) * 1978-06-09 1982-09-07 Delalande S.A. N-Aryl oxazolidinones, oxazolidinethiones, pyrrolidinones, pyrrolidines and thiazolidinones
FR2456097A1 (fr) * 1979-05-07 1980-12-05 Delalande Sa Nouveaux derives de la 5 h-furanone-2 et de la 3 h-dihydrofuranone-2, leur procede de preparation et leur application en therapeutique
US4226612A (en) * 1979-07-02 1980-10-07 Shell Oil Company Certain herbicidal (2-oxo-3-oxazolidinyl)phenylureas
CA1171865A (en) * 1980-06-04 1984-07-31 Alain Lacour N-aryl azolone derivatives, the process for preparing the same and their application in therapeutics
US4340606A (en) * 1980-10-23 1982-07-20 E. I. Du Pont De Nemours And Company 3-(p-Alkylsulfonylphenyl)oxazolidinone derivatives as antibacterial agents
FR2528046B1 (fr) * 1982-06-08 1985-06-21 Delalande Sa Derives de l'oxazolidinone-2 n-arylee optiquement actifs, inhibiteurs specifiques et reversibles de la monoamine oxydase de type b et leur procede de preparation
US5254577A (en) * 1988-07-29 1993-10-19 The Du Pont Merck Pharmaceutical Company Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents
US4948801A (en) * 1988-07-29 1990-08-14 E. I. Du Pont De Nemours And Company Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents
US5235063A (en) * 1989-10-17 1993-08-10 Delalande S.A. Process of preparing by condensation certain
US5196543A (en) * 1989-10-17 1993-03-23 Delalande S.A. 3-aryloxazolidinone derivatives, process for their preparation and their use in therapy
US5182296A (en) * 1989-10-26 1993-01-26 Tanabe Seiyaky Co., Ltd. Naphthyloxazolidone derivatives
TW286317B (es) * 1993-12-13 1996-09-21 Hoffmann La Roche
RU2175324C2 (ru) * 1995-09-01 2001-10-27 Фармация Энд Апджон Компани Фенилоксазолидиноны, имеющие с-с-связь с 4-8-членными гетероциклическими кольцами
CZ298060B6 (cs) * 1996-04-11 2007-06-06 Pharmacia & Upjohn Company Zpusob prípravy oxazolidinonu
KR100619639B1 (ko) 1997-11-07 2006-09-06 파마시아 앤드 업존 캄파니 엘엘씨 옥사졸리디논의 제조 방법
TR200003595T2 (tr) * 1998-06-05 2001-07-23 Astrazeneca Ab Kimyasal bileşikler
GB9928568D0 (en) 1999-12-03 2000-02-02 Zeneca Ltd Chemical compounds
GB0009803D0 (en) * 2000-04-25 2000-06-07 Astrazeneca Ab Chemical compounds
WO2002032857A1 (en) 2000-10-17 2002-04-25 Pharmacia & Upjohn Company Methods of producing oxazolidinone compounds
DE102008007802A1 (de) * 2008-02-06 2009-08-13 Sms Demag Ag Verfahren und Einrichtung zur Regelung von Stellgrößen in hütten-technischen Anlagen
WO2020147504A1 (en) * 2019-01-18 2020-07-23 Merck Sharp & Dohme Corp. Oxazolidinone compounds and methods of use thereof as antibacterial agents

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH8A (fr) * 1888-11-30 Kuhn & Tieche Nouveau mécanisme de remontoir et de mise à l'heure par le pendant pour montres de tous calibres
GB1180089A (en) * 1967-10-20 1970-02-04 Delalande Sa Acetylenic Derivatives of 2-Oxazolidinones and processes of preparation
GB1224995A (en) * 1968-09-20 1971-03-10 Delalande Sa New 5-propargyloxymethyl-2-substituted oxazolidinones and their process of preparation
GB1250538A (es) * 1969-03-18 1971-10-20

Also Published As

Publication number Publication date
MX4652E (es) 1982-07-16
GR60803B (en) 1978-08-30
BE851893A (fr) 1977-08-29
DE2708236A1 (de) 1977-09-08
US4150029A (en) 1979-04-17
CA1106380A (fr) 1981-08-04
JPS52113959A (en) 1977-09-24
CH618975A5 (es) 1980-08-29
FR2356422B1 (es) 1978-12-15
SE435928B (sv) 1984-10-29
JPS6040428B2 (ja) 1985-09-11
FR2356422A1 (fr) 1978-01-27
SE7702013L (sv) 1977-09-02
AU509376B2 (en) 1980-05-08
GB1546741A (en) 1979-05-31
AU2268977A (en) 1978-08-31
IT1071584B (it) 1985-04-10
LU76848A1 (fr) 1977-09-12
NL7702148A (nl) 1977-09-05
CH627460A5 (fr) 1982-01-15

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19861126