NO984878L - Fremstilling og anvendelse som medikamenter av 3-alkoksypyridin-2-karboksylsyreamidestere - Google Patents
Fremstilling og anvendelse som medikamenter av 3-alkoksypyridin-2-karboksylsyreamidestereInfo
- Publication number
- NO984878L NO984878L NO984878A NO984878A NO984878L NO 984878 L NO984878 L NO 984878L NO 984878 A NO984878 A NO 984878A NO 984878 A NO984878 A NO 984878A NO 984878 L NO984878 L NO 984878L
- Authority
- NO
- Norway
- Prior art keywords
- alkoxypyridine
- carboxylic acid
- amesters
- medicines
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Ophthalmology & Optometry (AREA)
- Gastroenterology & Hepatology (AREA)
- Pulmonology (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
Abstract
Det blir beskrevet 3-alkoksypyridin-2-karboksylsyreamidestere med formel (I), der R1, R2 og R3 betyr hydrogen, R4 betyr (Cj-C^-alkyl, A betyr en -CH2-gruppe, og et hydro- genatom kan bli erstattet med en metylgruppe, og B betyr -CO2G, hvori G betyr resten av en alkohol GOH, innbefattet fysiologisk virksomme salter; deres fremstilling, anven- delse for hemming av kollagenbiosyntese og deres anvendelse som legemiddel for be- handling av fibrotiske sykdommer.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/EP1996/001793 WO1997041103A1 (de) | 1996-04-30 | 1996-04-30 | 3-alkoxypyridin-2-carbonsäureamidester, ihre herstellung und ihre verwendung als arzneimittel |
Publications (2)
Publication Number | Publication Date |
---|---|
NO984878D0 NO984878D0 (no) | 1998-10-19 |
NO984878L true NO984878L (no) | 1998-12-29 |
Family
ID=8166212
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO984878A NO984878L (no) | 1996-04-30 | 1998-10-19 | Fremstilling og anvendelse som medikamenter av 3-alkoksypyridin-2-karboksylsyreamidestere |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP0900202A1 (no) |
JP (1) | JP2000509047A (no) |
KR (1) | KR20000065090A (no) |
AU (1) | AU5762896A (no) |
CA (1) | CA2253282A1 (no) |
NO (1) | NO984878L (no) |
WO (1) | WO1997041103A1 (no) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2803592A1 (fr) * | 2000-01-06 | 2001-07-13 | Aventis Cropscience Sa | Nouveaux derives de l'acide 3-hydroxypicolinique, leur procede de preparation et compositions fongicides les contenant. |
US20040146964A1 (en) | 2001-03-21 | 2004-07-29 | Maxwell Patrick Henry | Assays, methods and means |
ES2414706T3 (es) * | 2001-12-06 | 2013-07-22 | Fibrogen, Inc. | Métodos para aumentar la eritropoyetina endógena |
US7588924B2 (en) | 2006-03-07 | 2009-09-15 | Procter & Gamble Company | Crystal of hypoxia inducible factor 1 alpha prolyl hydroxylase |
EP3026044B8 (en) | 2006-06-26 | 2018-12-19 | Akebia Therapeutics, Inc. | Prolyl hydroxylase inhibitors and methods of use |
EP2496084B1 (en) | 2009-11-06 | 2015-06-10 | Aerpio Therapeutics Inc. | Compositions and methods for treating colitis |
NO2686520T3 (no) | 2011-06-06 | 2018-03-17 | ||
CA2837560C (en) | 2011-06-06 | 2017-02-14 | Akebia Therapeutics Inc. | Compounds and compositions for stabilizing hypoxia inducible factor-2 alpha as a method for treating cancer |
ES2666144T3 (es) | 2012-12-28 | 2018-05-03 | Dow Agrosciences Llc | Mezclas fungicidas sinérgicas para control fúngico en cereales |
CN114404414A (zh) | 2013-06-13 | 2022-04-29 | 阿克比治疗有限公司 | 用于治疗贫血症的组合物和方法 |
TWI665190B (zh) | 2013-11-15 | 2019-07-11 | 阿克比治療有限公司 | {[5-(3-氯苯基)-3-羥基吡啶-2-羰基]胺基}乙酸之固體型式,其組合物及用途 |
AU2015374458B2 (en) | 2014-12-30 | 2018-02-15 | Dow Agrosciences Llc | Use of picolinamide compounds with fungicidal activity |
WO2016109305A1 (en) | 2014-12-30 | 2016-07-07 | Dow Agrosciences Llc | Use of picolinamides as fungicides |
RU2703402C2 (ru) | 2014-12-30 | 2019-10-16 | ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи | Пиколинамиды с фунгицидной активностью |
RU2702697C2 (ru) * | 2014-12-30 | 2019-10-09 | ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи | Использование пиколинамидных соединений с фунгицидной активностью |
CA2972405A1 (en) | 2014-12-30 | 2016-07-07 | Dow Agrosciences Llc | Use of picolinamide compounds as fungicides |
US10150734B2 (en) | 2015-01-23 | 2018-12-11 | Akebia Therapeutics, Inc. | Solid forms of 2-(5-(3-fluorophenyl)-3-hydroxypicolinamido)acetic acid, compositions, and uses thereof |
BR112017021097B1 (pt) | 2015-04-01 | 2024-01-02 | Akebia Therapeutics, Inc | Formulação de dosagem oral e seu uso |
KR102473897B1 (ko) * | 2015-05-28 | 2022-12-06 | 니뽄 다바코 산교 가부시키가이샤 | 당뇨병성 신증을 치료 또는 예방하는 방법 |
EP3618626A4 (en) | 2017-05-02 | 2020-12-02 | Dow Agrosciences LLC | USE OF AN ACYCLIC PICOLINAMIDE COMPOUND AS A FUNGICIDE FOR FUNGAL GRASS INFESTATION |
TWI774761B (zh) | 2017-05-02 | 2022-08-21 | 美商科迪華農業科技有限責任公司 | 用於穀物中的真菌防治之協同性混合物 |
TW201842851A (zh) | 2017-05-02 | 2018-12-16 | 美商陶氏農業科學公司 | 用於穀類中的真菌防治之協同性混合物 |
BR102019004480B1 (pt) | 2018-03-08 | 2023-03-28 | Dow Agrosciences Llc | Picolinamidas como fungicidas |
TW202406895A (zh) | 2018-05-09 | 2024-02-16 | 美商阿克比治療有限公司 | 用於製備2-[[5-(3-氯苯基)-3-羥基吡啶-2-羰基]胺基]乙酸之方法 |
CA3115684A1 (en) | 2018-10-15 | 2020-04-23 | Dow Agrosciences Llc | Methods for sythesis of oxypicolinamides |
US11524939B2 (en) | 2019-11-13 | 2022-12-13 | Akebia Therapeutics, Inc. | Solid forms of {[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino} acetic acid |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0650960B1 (de) * | 1993-11-02 | 1997-03-05 | Hoechst Aktiengesellschaft | Substituierte heterocyclische Carbonsäureamidester, ihre Herstellung und ihre Verwendung als Arzneimittel |
-
1996
- 1996-04-30 EP EP96914152A patent/EP0900202A1/de not_active Withdrawn
- 1996-04-30 AU AU57628/96A patent/AU5762896A/en not_active Abandoned
- 1996-04-30 KR KR1019980708679A patent/KR20000065090A/ko not_active Application Discontinuation
- 1996-04-30 JP JP09538479A patent/JP2000509047A/ja active Pending
- 1996-04-30 CA CA002253282A patent/CA2253282A1/en not_active Abandoned
- 1996-04-30 WO PCT/EP1996/001793 patent/WO1997041103A1/de not_active Application Discontinuation
-
1998
- 1998-10-19 NO NO984878A patent/NO984878L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
AU5762896A (en) | 1997-11-19 |
NO984878D0 (no) | 1998-10-19 |
EP0900202A1 (de) | 1999-03-10 |
JP2000509047A (ja) | 2000-07-18 |
CA2253282A1 (en) | 1997-11-06 |
KR20000065090A (ko) | 2000-11-06 |
WO1997041103A1 (de) | 1997-11-06 |
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Legal Events
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FC2A | Withdrawal, rejection or dismissal of laid open patent application |