ES441233A1 - Procedimiento de obtencion de gangliosidos. - Google Patents
Procedimiento de obtencion de gangliosidos.Info
- Publication number
- ES441233A1 ES441233A1 ES441233A ES441233A ES441233A1 ES 441233 A1 ES441233 A1 ES 441233A1 ES 441233 A ES441233 A ES 441233A ES 441233 A ES441233 A ES 441233A ES 441233 A1 ES441233 A1 ES 441233A1
- Authority
- ES
- Spain
- Prior art keywords
- ethanol
- dialyzed
- lyophilized
- tetrahydrofuran
- methanol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000002270 gangliosides Chemical class 0.000 title abstract 3
- 229940079593 drug Drugs 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 238000000605 extraction Methods 0.000 title 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 6
- WYURNTSHIVDZCO-UHFFFAOYSA-N Tetrahydrofuran Chemical compound C1CCOC1 WYURNTSHIVDZCO-UHFFFAOYSA-N 0.000 abstract 4
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 2
- WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 abstract 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 abstract 2
- 238000005119 centrifugation Methods 0.000 abstract 2
- WORJEOGGNQDSOE-UHFFFAOYSA-N chloroform;methanol Chemical compound OC.ClC(Cl)Cl WORJEOGGNQDSOE-UHFFFAOYSA-N 0.000 abstract 2
- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 abstract 2
- KGBXLFKZBHKPEV-UHFFFAOYSA-N boric acid Chemical compound OB(O)O KGBXLFKZBHKPEV-UHFFFAOYSA-N 0.000 abstract 1
- 238000004090 dissolution Methods 0.000 abstract 1
- 239000003480 eluent Substances 0.000 abstract 1
- 238000005342 ion exchange Methods 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 238000005192 partition Methods 0.000 abstract 1
- 239000008363 phosphate buffer Substances 0.000 abstract 1
- 239000001103 potassium chloride Substances 0.000 abstract 1
- 235000011164 potassium chloride Nutrition 0.000 abstract 1
- 239000002244 precipitate Substances 0.000 abstract 1
- 238000000926 separation method Methods 0.000 abstract 1
- 239000000377 silicon dioxide Substances 0.000 abstract 1
- 239000006228 supernatant Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/30—Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cell Biology (AREA)
- Developmental Biology & Embryology (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Ophthalmology & Optometry (AREA)
- Virology (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Extraction Or Liquid Replacement (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT26323/75A IT1046051B (it) | 1975-08-13 | 1975-08-13 | Nuova applicazione terapeutica dei gangliosidi e procedimento per la loro estrazione |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES441233A1 true ES441233A1 (es) | 1977-03-16 |
Family
ID=11219226
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES441233A Expired ES441233A1 (es) | 1975-08-13 | 1975-09-24 | Procedimiento de obtencion de gangliosidos. |
Country Status (7)
| Country | Link |
|---|---|
| JP (2) | JPS5234912A (cg-RX-API-DMAC7.html) |
| AT (1) | AT352296B (cg-RX-API-DMAC7.html) |
| BE (1) | BE843695A (cg-RX-API-DMAC7.html) |
| DE (1) | DE2549680A1 (cg-RX-API-DMAC7.html) |
| ES (1) | ES441233A1 (cg-RX-API-DMAC7.html) |
| FR (1) | FR2320760A1 (cg-RX-API-DMAC7.html) |
| IT (1) | IT1046051B (cg-RX-API-DMAC7.html) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2451194A1 (fr) * | 1979-03-16 | 1980-10-10 | Merieux Inst | Nouveau medicament a base de ganglioside notamment pour le traitement du cholera, et compositions pharmaceutiques le contenant |
| WO1980001875A1 (fr) * | 1979-03-16 | 1980-09-18 | Merieux Inst | Nouveau medicament, notamment pour le traitement du cholera, et compositions pharmaceutiques le contenant |
| CA1168980A (en) * | 1980-04-17 | 1984-06-12 | Rolf Schafer | Wound healing compositions |
| EP0058665B1 (en) * | 1980-05-09 | 1986-02-26 | LEFFLER, Hakon | Carbohydrate derivatives for inhibiting bacterial adherence |
| EP0126817B1 (en) * | 1983-05-27 | 1989-04-19 | Shanksville Corporation N.V. | Suppressing of graft rejection in organ transplantation |
| JPS59222424A (ja) * | 1983-06-01 | 1984-12-14 | Katsutaka Nagai | 神経障害疾患治療剤 |
| IT1177863B (it) * | 1984-07-03 | 1987-08-26 | Fidia Farmaceutici | Una miscela gangliosidica come agente terapeutico capare di eliminare il dolore nele neuropatie periferiche |
| JPH01228997A (ja) * | 1988-03-10 | 1989-09-12 | Mect Corp | シアロシルグリセライド類及びその製造方法 |
| US5073543A (en) * | 1988-07-21 | 1991-12-17 | G. D. Searle & Co. | Controlled release formulations of trophic factors in ganglioside-lipsome vehicle |
| AR241751A1 (es) * | 1989-07-12 | 1992-12-30 | Beta Lab Sa | Procedimiento para obtener mezclas de gangliosidos para el tratamiento de enfermedades psico-organicas y del caracter. |
| IT1232176B (it) | 1989-07-27 | 1992-01-25 | Fidia Farmaceutici | Derivati di-lisogangliosidi |
| IT1238346B (it) * | 1989-11-14 | 1993-07-13 | Gangliosidi modificati e loro derivati funzionali. | |
| JPH0580009A (ja) * | 1991-09-20 | 1993-03-30 | Kubota Corp | 炭酸濃度測定方法 |
| JPH0580010A (ja) * | 1991-09-25 | 1993-03-30 | Kubota Corp | 気体中の炭酸ガス濃度測定方法 |
| RU2195296C2 (ru) * | 2000-04-12 | 2002-12-27 | Ставропольский научно-исследовательский противочумный институт | Способ получения ганглиозидов |
| RU2192871C2 (ru) * | 2000-11-22 | 2002-11-20 | Нижегородское государственное предприятие по производству бактерийных препаратов - ИмБио | Способ получения биологически активного комплекса из животного сырья для терапевтического использования |
| JP4005115B1 (ja) * | 2007-02-08 | 2007-11-07 | 日本臓器製薬株式会社 | 疼痛疾患治療剤 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT127981B (de) * | 1929-06-07 | 1932-04-25 | Schering Kahlbaum Ag | Verfahren zur Herstellung eines die zentralen Tätigkeiten fördernden und regulierenden Reizstoffes. |
| CH193176A (de) * | 1936-12-08 | 1937-09-30 | Richter Arthur | Verfahren zur Gewinnung eines Wirkstoffes aus Säugetiergehirn. |
| US3436413A (en) * | 1965-12-21 | 1969-04-01 | Canada Packers Ltd | Process for the isolation of phosphatidyl serine |
-
1975
- 1975-08-13 IT IT26323/75A patent/IT1046051B/it active Protection Beyond IP Right Term
- 1975-09-24 ES ES441233A patent/ES441233A1/es not_active Expired
- 1975-11-05 DE DE19752549680 patent/DE2549680A1/de active Granted
- 1975-12-30 FR FR7540170A patent/FR2320760A1/fr active Granted
-
1976
- 1976-07-01 BE BE168566A patent/BE843695A/xx not_active IP Right Cessation
- 1976-08-13 JP JP51097402A patent/JPS5234912A/ja active Granted
- 1976-08-13 AT AT606976A patent/AT352296B/de not_active IP Right Cessation
-
1987
- 1987-01-05 JP JP62000347A patent/JPS62187412A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| BE843695A (fr) | 1976-11-03 |
| DE2549680A1 (de) | 1977-02-24 |
| ATA606976A (de) | 1979-02-15 |
| JPS6256134B2 (cg-RX-API-DMAC7.html) | 1987-11-24 |
| IT1046051B (it) | 1980-06-30 |
| FR2320760B1 (cg-RX-API-DMAC7.html) | 1978-11-17 |
| AT352296B (de) | 1979-09-10 |
| DE2549680C2 (cg-RX-API-DMAC7.html) | 1988-05-11 |
| FR2320760A1 (fr) | 1977-03-11 |
| JPS62187412A (ja) | 1987-08-15 |
| JPS6250450B2 (cg-RX-API-DMAC7.html) | 1987-10-24 |
| JPS5234912A (en) | 1977-03-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19941119 |