FR2451194A1 - Nouveau medicament a base de ganglioside notamment pour le traitement du cholera, et compositions pharmaceutiques le contenant - Google Patents

Nouveau medicament a base de ganglioside notamment pour le traitement du cholera, et compositions pharmaceutiques le contenant

Info

Publication number
FR2451194A1
FR2451194A1 FR7906732A FR7906732A FR2451194A1 FR 2451194 A1 FR2451194 A1 FR 2451194A1 FR 7906732 A FR7906732 A FR 7906732A FR 7906732 A FR7906732 A FR 7906732A FR 2451194 A1 FR2451194 A1 FR 2451194A1
Authority
FR
France
Prior art keywords
esp
moles
ganglioside
diarrhoea
contg
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7906732A
Other languages
English (en)
Other versions
FR2451194B1 (fr
Inventor
Marie Claude Mynard
Jean Louis Tayot
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut Merieux SA
Original Assignee
Institut Merieux SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institut Merieux SA filed Critical Institut Merieux SA
Priority to FR7906732A priority Critical patent/FR2451194A1/fr
Priority to PCT/FR1980/000037 priority patent/WO1980001875A1/fr
Priority to US06/217,114 priority patent/US4347244A/en
Priority to EP80400353A priority patent/EP0016702B1/fr
Priority to DE8080400353T priority patent/DE3070189D1/de
Priority to JP50067380A priority patent/JPS56500138A/ja
Publication of FR2451194A1 publication Critical patent/FR2451194A1/fr
Application granted granted Critical
Publication of FR2451194B1 publication Critical patent/FR2451194B1/fr
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/143—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/30—Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6921—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Cell Biology (AREA)
  • Biomedical Technology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Inorganic Chemistry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

NOUVEAU MEDICAMENT ET COMPOSITIONS PHARMACEUTIQUES LE CONTENANT. CE MEDICAMENT EST CARACTERISE PAR LE FAIT QU'IL EST CONSTITUE PAR UN SUPPORT SUR LEQUEL EST FIXE UN GANGLIOSIDE OU UN DERIVE DE GANGLIOSIDE DOUE D'AFFINITE POUR LES TOXINES PRODUITES PAR DES BACTERIES RESPONSABLES DES DIARRHEES, ET NOTAMMENT POUR LA TOXINE CHOLERIQUE. APPLICATION AU TRAITEMENT PREVENTIF OU CURATIF DES DIARRHEES AIGUES ET NOTAMMENT DU CHOLERA.
FR7906732A 1979-03-16 1979-03-16 Nouveau medicament a base de ganglioside notamment pour le traitement du cholera, et compositions pharmaceutiques le contenant Granted FR2451194A1 (fr)

Priority Applications (6)

Application Number Priority Date Filing Date Title
FR7906732A FR2451194A1 (fr) 1979-03-16 1979-03-16 Nouveau medicament a base de ganglioside notamment pour le traitement du cholera, et compositions pharmaceutiques le contenant
PCT/FR1980/000037 WO1980001875A1 (fr) 1979-03-16 1980-03-17 Nouveau medicament, notamment pour le traitement du cholera, et compositions pharmaceutiques le contenant
US06/217,114 US4347244A (en) 1979-03-16 1980-03-17 Ganglioside containing compositions for treating diarrhea
EP80400353A EP0016702B1 (fr) 1979-03-16 1980-03-17 Médicament, notamment pour le traitement du choléra, et compositions pharmaceutiques le contenant
DE8080400353T DE3070189D1 (en) 1979-03-16 1980-03-17 Medicament, particularly for the treatment of cholera, and pharmaceutical compositions containing it
JP50067380A JPS56500138A (fr) 1979-03-16 1980-03-17

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7906732A FR2451194A1 (fr) 1979-03-16 1979-03-16 Nouveau medicament a base de ganglioside notamment pour le traitement du cholera, et compositions pharmaceutiques le contenant

Publications (2)

Publication Number Publication Date
FR2451194A1 true FR2451194A1 (fr) 1980-10-10
FR2451194B1 FR2451194B1 (fr) 1983-11-10

Family

ID=9223206

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7906732A Granted FR2451194A1 (fr) 1979-03-16 1979-03-16 Nouveau medicament a base de ganglioside notamment pour le traitement du cholera, et compositions pharmaceutiques le contenant

Country Status (1)

Country Link
FR (1) FR2451194A1 (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0036372A1 (fr) * 1980-03-17 1981-09-23 Institut Merieux Nouveaux dérivés de gangliosides, leur préparation et leur application
EP0097059A2 (fr) * 1982-06-16 1983-12-28 Unilever N.V. Compositions pour le traitement de la peau
WO2006125496A2 (fr) * 2005-05-26 2006-11-30 Flamma S.P.A. Formulations pharmaceutiques renfermant des principes actifs pharmaceutiques absorbes sur des nanoparticules de dioxyde de titane

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2319399A1 (fr) * 1975-07-29 1977-02-25 Merieux Inst Nouveau materiau a caractere cationique, capable de fixer de facon reversible, des macromolecules biologiques, procedes de preparation et applications
FR2320760A1 (fr) * 1975-08-13 1977-03-11 Fidia Spa Utilisation therapeutique nouvelle des gangliosides et procede pour leur extraction

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2319399A1 (fr) * 1975-07-29 1977-02-25 Merieux Inst Nouveau materiau a caractere cationique, capable de fixer de facon reversible, des macromolecules biologiques, procedes de preparation et applications
FR2320760A1 (fr) * 1975-08-13 1977-03-11 Fidia Spa Utilisation therapeutique nouvelle des gangliosides et procede pour leur extraction

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0036372A1 (fr) * 1980-03-17 1981-09-23 Institut Merieux Nouveaux dérivés de gangliosides, leur préparation et leur application
EP0097059A2 (fr) * 1982-06-16 1983-12-28 Unilever N.V. Compositions pour le traitement de la peau
EP0097059A3 (en) * 1982-06-16 1985-07-10 Unilever Nv Skin treatment compositions
WO2006125496A2 (fr) * 2005-05-26 2006-11-30 Flamma S.P.A. Formulations pharmaceutiques renfermant des principes actifs pharmaceutiques absorbes sur des nanoparticules de dioxyde de titane
WO2006125496A3 (fr) * 2005-05-26 2007-04-12 Flamma Spa Formulations pharmaceutiques renfermant des principes actifs pharmaceutiques absorbes sur des nanoparticules de dioxyde de titane

Also Published As

Publication number Publication date
FR2451194B1 (fr) 1983-11-10

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