ES435753A1 - Procedimiento para la preparacion de amidas aromaticas de compuestos heterociclicos. - Google Patents
Procedimiento para la preparacion de amidas aromaticas de compuestos heterociclicos.Info
- Publication number
- ES435753A1 ES435753A1 ES435753A ES435753A ES435753A1 ES 435753 A1 ES435753 A1 ES 435753A1 ES 435753 A ES435753 A ES 435753A ES 435753 A ES435753 A ES 435753A ES 435753 A1 ES435753 A1 ES 435753A1
- Authority
- ES
- Spain
- Prior art keywords
- alkyl
- substituted
- radical
- hydrogen
- aryl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000008430 aromatic amides Chemical class 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 title 1
- 125000003118 aryl group Chemical group 0.000 abstract 6
- 239000001257 hydrogen Substances 0.000 abstract 4
- 229910052739 hydrogen Inorganic materials 0.000 abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 150000001558 benzoic acid derivatives Chemical class 0.000 abstract 3
- 150000002431 hydrogen Chemical class 0.000 abstract 3
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 3
- WPYMKLBDIGXBTP-UHFFFAOYSA-N Benzoic acid Natural products OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 abstract 2
- 239000005711 Benzoic acid Substances 0.000 abstract 2
- -1 N-imidazolamide Chemical class 0.000 abstract 2
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 2
- WYURNTSHIVDZCO-UHFFFAOYSA-N Tetrahydrofuran Chemical compound C1CCOC1 WYURNTSHIVDZCO-UHFFFAOYSA-N 0.000 abstract 2
- YTPLMLYBLZKORZ-UHFFFAOYSA-N Thiophene Chemical compound C=1C=CSC=1 YTPLMLYBLZKORZ-UHFFFAOYSA-N 0.000 abstract 2
- 125000004442 acylamino group Chemical group 0.000 abstract 2
- 125000004103 aminoalkyl group Chemical group 0.000 abstract 2
- 150000008064 anhydrides Chemical class 0.000 abstract 2
- 125000003435 aroyl group Chemical group 0.000 abstract 2
- 235000010233 benzoic acid Nutrition 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- 125000005842 heteroatom Chemical group 0.000 abstract 2
- 125000000623 heterocyclic group Chemical group 0.000 abstract 2
- 125000004191 (C1-C6) alkoxy group Chemical group 0.000 abstract 1
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- CZPWVGJYEJSRLH-UHFFFAOYSA-N Pyrimidine Chemical compound C1=CN=CN=C1 CZPWVGJYEJSRLH-UHFFFAOYSA-N 0.000 abstract 1
- 125000003282 alkyl amino group Chemical group 0.000 abstract 1
- 125000005907 alkyl ester group Chemical group 0.000 abstract 1
- 150000005215 alkyl ethers Chemical class 0.000 abstract 1
- 125000005422 alkyl sulfonamido group Chemical group 0.000 abstract 1
- 125000004390 alkyl sulfonyl group Chemical group 0.000 abstract 1
- 150000004945 aromatic hydrocarbons Chemical class 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 150000001540 azides Chemical class 0.000 abstract 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 1
- 229910052794 bromium Inorganic materials 0.000 abstract 1
- 150000008280 chlorinated hydrocarbons Chemical class 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 150000004292 cyclic ethers Chemical class 0.000 abstract 1
- 125000004663 dialkyl amino group Chemical group 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 229910052731 fluorine Inorganic materials 0.000 abstract 1
- 239000011737 fluorine Substances 0.000 abstract 1
- 150000004820 halides Chemical class 0.000 abstract 1
- 125000001188 haloalkyl group Chemical group 0.000 abstract 1
- 150000002391 heterocyclic compounds Chemical class 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 239000012442 inert solvent Substances 0.000 abstract 1
- 125000000449 nitro group Chemical class [O-][N+](*)=O 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 abstract 1
- 229940124530 sulfonamide Drugs 0.000 abstract 1
- 150000003456 sulfonamides Chemical class 0.000 abstract 1
- 125000005420 sulfonamido group Chemical group S(=O)(=O)(N*)* 0.000 abstract 1
- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 abstract 1
- 229930192474 thiophene Natural products 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
- C07D211/28—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms to which a second hetero atom is attached
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Otolaryngology (AREA)
- Rheumatology (AREA)
- Hospice & Palliative Care (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB12572/74A GB1507462A (en) | 1974-03-21 | 1974-03-21 | N-heterocyclic substituted benzamides methods for their preparation and compositions containing them |
| GB3540274 | 1974-08-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES435753A1 true ES435753A1 (es) | 1977-04-01 |
Family
ID=26249107
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES435753A Expired ES435753A1 (es) | 1974-03-21 | 1975-03-18 | Procedimiento para la preparacion de amidas aromaticas de compuestos heterociclicos. |
| ES435756A Expired ES435756A1 (es) | 1974-03-21 | 1975-03-18 | Procedimiento para la preparacion de amidas aromaticas de compuestos heterociclicos. |
| ES435757A Expired ES435757A1 (es) | 1974-03-21 | 1975-03-18 | Procedimiento para la preparacion de amidas aromaticas de compuestos heterociclicos. |
| ES435755A Expired ES435755A1 (es) | 1974-03-21 | 1975-03-18 | Procedimiento para la preparacion de amidas aromaticas de compuestos heterociclicos. |
| ES435754A Expired ES435754A1 (es) | 1974-03-21 | 1975-03-18 | Procedimiento para la preparacion de amidas aromaticas de compuestos heterociclicos. |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES435756A Expired ES435756A1 (es) | 1974-03-21 | 1975-03-18 | Procedimiento para la preparacion de amidas aromaticas de compuestos heterociclicos. |
| ES435757A Expired ES435757A1 (es) | 1974-03-21 | 1975-03-18 | Procedimiento para la preparacion de amidas aromaticas de compuestos heterociclicos. |
| ES435755A Expired ES435755A1 (es) | 1974-03-21 | 1975-03-18 | Procedimiento para la preparacion de amidas aromaticas de compuestos heterociclicos. |
| ES435754A Expired ES435754A1 (es) | 1974-03-21 | 1975-03-18 | Procedimiento para la preparacion de amidas aromaticas de compuestos heterociclicos. |
Country Status (11)
| Country | Link |
|---|---|
| JP (1) | JPS584019B2 (enEXAMPLES) |
| AR (1) | AR216043A1 (enEXAMPLES) |
| CH (1) | CH602641A5 (enEXAMPLES) |
| DK (1) | DK147854C (enEXAMPLES) |
| ES (5) | ES435753A1 (enEXAMPLES) |
| FI (1) | FI60200C (enEXAMPLES) |
| FR (1) | FR2264530A1 (enEXAMPLES) |
| KE (1) | KE2900A (enEXAMPLES) |
| NL (1) | NL159660B (enEXAMPLES) |
| NO (1) | NO144108C (enEXAMPLES) |
| SE (1) | SE427750B (enEXAMPLES) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1513631A (en) * | 1976-02-17 | 1978-06-07 | Gallardo Antonio Sa | Piperidine derivatives |
| GB1561023A (en) * | 1977-04-22 | 1980-02-13 | Beecham Group Ltd | 2-methoxy - 5 - chloro aniline derivatives |
| FR2446274A1 (fr) * | 1979-01-15 | 1980-08-08 | Delalande Sa | Nouveaux derives de salicylamide, leur procede de preparation et leur application en therapeutique |
| EP0343307A1 (en) * | 1988-05-26 | 1989-11-29 | Fabrica Espanola De Productos Quimicos Y Farmaceuticos, S.A. | 4-Piperidinealkanamine derivatives |
| FR2674849B1 (fr) * | 1991-04-02 | 1994-12-23 | Logeais Labor Jacques | Nouveaux derives de n-cyclohexyl benzamides ou thiobenzamides, leurs preparations et leurs applications en therapeutique. |
| FR2766486B1 (fr) * | 1997-07-25 | 1999-09-17 | Logeais Labor Jacques | Cycloalkyles benzamides stimulants de la motricite gastrointestinale haute et basse |
| FR2766484B1 (fr) * | 1997-07-25 | 1999-09-17 | Logeais Labor Jacques | Nouveaux derives benzamides stimulants de la motricite gastrointestinale haute et basse |
| PL1893603T3 (pl) * | 2005-06-02 | 2010-03-31 | Hoffmann La Roche | Pochodne piperydyn-4-yloamidowe i ich zastosowanie jako antagonistów podtypu 5 receptora SST |
| KR100976063B1 (ko) * | 2007-03-16 | 2010-08-17 | 동아제약주식회사 | 신규한 벤즈아미드 유도체 화합물 및 그의 제조방법 |
| PL2786986T3 (pl) * | 2011-11-29 | 2018-08-31 | Vivozon, Inc. | Nowa pochodna benzamidu i jej zastosowanie |
-
1975
- 1975-03-17 AR AR257994A patent/AR216043A1/es active
- 1975-03-18 ES ES435753A patent/ES435753A1/es not_active Expired
- 1975-03-18 ES ES435756A patent/ES435756A1/es not_active Expired
- 1975-03-18 ES ES435757A patent/ES435757A1/es not_active Expired
- 1975-03-18 ES ES435755A patent/ES435755A1/es not_active Expired
- 1975-03-18 ES ES435754A patent/ES435754A1/es not_active Expired
- 1975-03-20 FR FR7509371A patent/FR2264530A1/fr active Granted
- 1975-03-20 DK DK117675A patent/DK147854C/da not_active IP Right Cessation
- 1975-03-20 NO NO750957A patent/NO144108C/no unknown
- 1975-03-20 SE SE7503196A patent/SE427750B/xx not_active IP Right Cessation
- 1975-03-20 CH CH355075A patent/CH602641A5/xx not_active IP Right Cessation
- 1975-03-20 FI FI750825A patent/FI60200C/fi not_active IP Right Cessation
- 1975-03-21 NL NL7503417.A patent/NL159660B/xx not_active IP Right Cessation
- 1975-03-22 JP JP7534871A patent/JPS584019B2/ja not_active Expired
-
1978
- 1978-11-14 KE KE2900A patent/KE2900A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FI750825A7 (enEXAMPLES) | 1975-09-22 |
| DK117675A (enEXAMPLES) | 1975-09-22 |
| ES435756A1 (es) | 1977-04-01 |
| FR2264530A1 (en) | 1975-10-17 |
| NO144108C (no) | 1981-06-24 |
| ES435754A1 (es) | 1977-04-01 |
| DK147854C (da) | 1985-07-22 |
| SE427750B (sv) | 1983-05-02 |
| KE2900A (en) | 1978-12-01 |
| NO144108B (no) | 1981-03-16 |
| CH602641A5 (enEXAMPLES) | 1978-07-31 |
| AR216043A1 (es) | 1979-11-30 |
| JPS50129573A (enEXAMPLES) | 1975-10-13 |
| JPS584019B2 (ja) | 1983-01-24 |
| NL7503417A (nl) | 1975-09-23 |
| NL159660B (nl) | 1979-03-15 |
| ES435755A1 (es) | 1977-04-01 |
| DK147854B (da) | 1984-12-24 |
| FI60200C (fi) | 1981-12-10 |
| FR2264530B1 (enEXAMPLES) | 1978-11-10 |
| SE7503196L (enEXAMPLES) | 1975-09-22 |
| ES435757A1 (es) | 1977-04-01 |
| FI60200B (fi) | 1981-08-31 |
| NO750957L (enEXAMPLES) | 1975-09-23 |
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