FR2766486B1 - Cycloalkyles benzamides stimulants de la motricite gastrointestinale haute et basse - Google Patents

Cycloalkyles benzamides stimulants de la motricite gastrointestinale haute et basse

Info

Publication number
FR2766486B1
FR2766486B1 FR9709478A FR9709478A FR2766486B1 FR 2766486 B1 FR2766486 B1 FR 2766486B1 FR 9709478 A FR9709478 A FR 9709478A FR 9709478 A FR9709478 A FR 9709478A FR 2766486 B1 FR2766486 B1 FR 2766486B1
Authority
FR
France
Prior art keywords
cycloalkyles
benzamide
gastrointestinal motor
low gastrointestinal
motor stimulating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9709478A
Other languages
English (en)
Other versions
FR2766486A1 (fr
Inventor
Christian Jeanpetit
Thierry Bouyssou
Helene Christinaki
Serge Biosa
Olivier Boucheix
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratoires Jacques Logeais SA
Original Assignee
Laboratoires Jacques Logeais SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoires Jacques Logeais SA filed Critical Laboratoires Jacques Logeais SA
Priority to FR9709478A priority Critical patent/FR2766486B1/fr
Priority to TNTNSN98137A priority patent/TNSN98137A1/fr
Priority to PCT/FR1998/001641 priority patent/WO1999005133A1/fr
Priority to EP98940330A priority patent/EP0998469A1/fr
Priority to ARP980103646A priority patent/AR014901A1/es
Priority to CO98042279A priority patent/CO4990983A1/es
Priority to ZA986632A priority patent/ZA986632B/xx
Priority to AU88679/98A priority patent/AU8867998A/en
Publication of FR2766486A1 publication Critical patent/FR2766486A1/fr
Application granted granted Critical
Publication of FR2766486B1 publication Critical patent/FR2766486B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Nutrition Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
FR9709478A 1997-07-25 1997-07-25 Cycloalkyles benzamides stimulants de la motricite gastrointestinale haute et basse Expired - Fee Related FR2766486B1 (fr)

Priority Applications (8)

Application Number Priority Date Filing Date Title
FR9709478A FR2766486B1 (fr) 1997-07-25 1997-07-25 Cycloalkyles benzamides stimulants de la motricite gastrointestinale haute et basse
TNTNSN98137A TNSN98137A1 (fr) 1997-07-25 1998-07-15 Cycloalkyles benzamides stimulants de la motricite gastrointestinale haute et basse
EP98940330A EP0998469A1 (fr) 1997-07-25 1998-07-24 Cycloalkyles benzamides stimulants de la motricite gastrointestinale haute et basse
ARP980103646A AR014901A1 (es) 1997-07-25 1998-07-24 Compuestos n-[(alquil-1-piperidin-4-sustituida)cicloalquil]benzamidas, composicion farmaceutica que los comprende y su uso
PCT/FR1998/001641 WO1999005133A1 (fr) 1997-07-25 1998-07-24 Cycloalkyles benzamides stimulants de la motricite gastrointestinale haute et basse
CO98042279A CO4990983A1 (es) 1997-07-25 1998-07-24 Cicloalquilos benzamidas estimulantes de la motricidad gastrointestinal alta y baja
ZA986632A ZA986632B (en) 1997-07-25 1998-07-24 Cycloalkylbenzamides which stimulate upper and lower gastrointestinal motoricity
AU88679/98A AU8867998A (en) 1997-07-25 1998-07-24 Benzamide cycloalkyl stimulating high and low gastrointestinal motricity

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9709478A FR2766486B1 (fr) 1997-07-25 1997-07-25 Cycloalkyles benzamides stimulants de la motricite gastrointestinale haute et basse

Publications (2)

Publication Number Publication Date
FR2766486A1 FR2766486A1 (fr) 1999-01-29
FR2766486B1 true FR2766486B1 (fr) 1999-09-17

Family

ID=9509624

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9709478A Expired - Fee Related FR2766486B1 (fr) 1997-07-25 1997-07-25 Cycloalkyles benzamides stimulants de la motricite gastrointestinale haute et basse

Country Status (8)

Country Link
EP (1) EP0998469A1 (fr)
AR (1) AR014901A1 (fr)
AU (1) AU8867998A (fr)
CO (1) CO4990983A1 (fr)
FR (1) FR2766486B1 (fr)
TN (1) TNSN98137A1 (fr)
WO (1) WO1999005133A1 (fr)
ZA (1) ZA986632B (fr)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1015921A (en) * 1961-10-06 1966-01-05 Benger Lab Ltd Benzamides
AR216043A1 (es) * 1974-03-21 1979-11-30 Anphar Sa Procedimiento para la preparacion de 1-derivados de benzoilamino-4-piperidina y sus sales fisiologicamente aceptables
EP0222533A1 (fr) * 1985-10-25 1987-05-20 The Upjohn Company Cis-N-[(2-aminocycloaliphatique)-benzèneacétamide et -benzamides anticonvulsifs
FR2674849B1 (fr) * 1991-04-02 1994-12-23 Logeais Labor Jacques Nouveaux derives de n-cyclohexyl benzamides ou thiobenzamides, leurs preparations et leurs applications en therapeutique.
WO1996005166A1 (fr) * 1994-08-11 1996-02-22 Yamanouchi Pharmaceutical Co., Ltd. Derive d'amine substitue et composition medicamenteuse le contenant
FR2735693B1 (fr) * 1995-06-23 1997-09-26 Logeais Labor Jacques Nouvelles applications therapeutiques de n-cyclohexyl benzamides

Also Published As

Publication number Publication date
AU8867998A (en) 1999-02-16
ZA986632B (en) 1999-02-04
CO4990983A1 (es) 2000-12-26
TNSN98137A1 (fr) 2005-03-15
FR2766486A1 (fr) 1999-01-29
AR014901A1 (es) 2001-04-11
EP0998469A1 (fr) 2000-05-10
WO1999005133A1 (fr) 1999-02-04

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Legal Events

Date Code Title Description
ST Notification of lapse