ES426272A1 - Un procedimiento para la conversion de un acido 3-aciloxi- metil-cef-3-em-4-carboxilico en su analogo de 3-hidroximeti-lo. - Google Patents

Un procedimiento para la conversion de un acido 3-aciloxi- metil-cef-3-em-4-carboxilico en su analogo de 3-hidroximeti-lo.

Info

Publication number
ES426272A1
ES426272A1 ES426272A ES426272A ES426272A1 ES 426272 A1 ES426272 A1 ES 426272A1 ES 426272 A ES426272 A ES 426272A ES 426272 A ES426272 A ES 426272A ES 426272 A1 ES426272 A1 ES 426272A1
Authority
ES
Spain
Prior art keywords
preparation
cephalosporin compounds
microorganism
cephalosporin
rhodotorula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES426272A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Laboratories Ltd
Original Assignee
Glaxo Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Laboratories Ltd filed Critical Glaxo Laboratories Ltd
Publication of ES426272A1 publication Critical patent/ES426272A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18—Carboxylic ester hydrolases (3.1.1)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/911—Microorganisms using fungi
ES426272A 1973-05-14 1974-05-13 Un procedimiento para la conversion de un acido 3-aciloxi- metil-cef-3-em-4-carboxilico en su analogo de 3-hidroximeti-lo. Expired ES426272A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2279973A GB1474519A (es) 1973-05-14 1973-05-14

Publications (1)

Publication Number Publication Date
ES426272A1 true ES426272A1 (es) 1976-07-01

Family

ID=10185247

Family Applications (1)

Application Number Title Priority Date Filing Date
ES426272A Expired ES426272A1 (es) 1973-05-14 1974-05-13 Un procedimiento para la conversion de un acido 3-aciloxi- metil-cef-3-em-4-carboxilico en su analogo de 3-hidroximeti-lo.

Country Status (12)

Country Link
US (1) US3912589A (es)
JP (1) JPS5443598B2 (es)
AT (1) AT335057B (es)
BE (1) BE814937A (es)
CA (1) CA1021280A (es)
CH (1) CH606002A5 (es)
DE (1) DE2423058C2 (es)
ES (1) ES426272A1 (es)
FR (1) FR2229701B1 (es)
GB (1) GB1474519A (es)
NL (1) NL159716B (es)
ZA (1) ZA743023B (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3976546A (en) * 1974-11-08 1976-08-24 Glaxo Laboratories Limited Cephalosporins
JPS5423372A (en) * 1977-07-22 1979-02-21 Hitachi Ltd Counter circuit
US4162193A (en) * 1977-08-19 1979-07-24 Merck & Co., Inc. Enzymatic cleavage of N-acyl-thienamycins
US4135978A (en) * 1977-08-19 1979-01-23 Merck & Co., Inc. Production of n-acyl-thienamycins
FR2461753A1 (fr) * 1979-07-19 1981-02-06 Glaxo Group Ltd Procede de preparation d'une cephalosporine par fermentation et micro-organisme destine a la mise en oeuvre de ce procede
US4414328A (en) 1980-07-21 1983-11-08 Fujisawa Pharmaceutical Co., Ltd. Process for the preparation of deacetylcephalosporin C
US4474879A (en) * 1982-11-16 1984-10-02 Eli Lilly And Company Process for 3-hydroxymethyl cephalosporin sulfones
DE3432060A1 (de) * 1984-08-31 1986-03-06 Bayer Ag, 5090 Leverkusen Immobilisierte zellen von bacillus subtilis, immobilisierungsverfahren und verwendung des praeparats zur abspaltung der 3-acetoxygruppe aus 7-ss-acylamido-cephalosporansaeuren
US4872899A (en) * 1985-04-02 1989-10-10 Utah State University Foundation Treatment of plant chlorosis with rhodotorulic acid
DE69022909T2 (de) * 1989-07-19 1996-04-11 Lilly Co Eli Enzymatische Oxidation von Ceph C zu Glutaryl-7-Aminocephalosporansäure.
IT1247964B (it) * 1991-06-03 1995-01-05 Ministero Dell Uni E Della Processo per la preparazione enzimatica di derivati cefalosporanici
US5512454A (en) * 1994-02-03 1996-04-30 Bristol-Myers Squibb Company Enzymatic acylation of 3-hydroxymethyl cephalosporins
JPH09504306A (ja) * 1994-07-22 1997-04-28 アンテイビオテイコス・エツセ・ピー・アー グリタリル７−ａｃａ誘導体とその調整のためのプロセス
US6080590A (en) * 1995-04-21 2000-06-27 Rijksuniversiteit Te Leiden On-line coupling biochemical detection to continuous flow separation techniques
AT411996B (de) * 2000-09-11 2004-08-26 Sandoz Ag Verfahren zur herstellung von cefuroxim in der form seines n-butylammoniumsalzes
CN102702231B (zh) * 2012-06-18 2014-10-29 山东大学 一种3-去氨甲酰基-头孢呋辛酸的制备方法
CN109553629B (zh) * 2018-12-26 2020-06-23 浙江永宁药业股份有限公司 一种头孢呋辛钠中间体e型杂质化合物的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH475284A (de) * 1963-11-19 1969-07-15 Ciba Geigy Verfahren zur Herstellung von Desacetyl-7-amino-cephalosporansäure
DE1445639B2 (de) * 1963-11-19 1976-09-09 Ciba-Geigy Ag, Basel (Schweiz) Verfahren zur herstellung von desacetyl-7-aminocephalosporansaeure
GB1121308A (en) * 1964-10-30 1968-07-24 Glaxo Lab Ltd Cephalosporins
FR1460131A (fr) * 1964-10-30 1966-06-17 Glaxo Lab Ltd Procédé de préparation de produits de dégradation de la céphalosporine c et de ses dérivés

Also Published As

Publication number Publication date
GB1474519A (es) 1977-05-25
FR2229701B1 (es) 1978-02-17
ATA392874A (de) 1976-06-15
NL7406418A (es) 1974-11-18
NL159716B (nl) 1979-03-15
FR2229701A1 (es) 1974-12-13
US3912589A (en) 1975-10-14
BE814937A (fr) 1974-11-13
AU6885574A (en) 1975-11-13
CA1021280A (en) 1977-11-22
AT335057B (de) 1977-02-25
JPS5443598B2 (es) 1979-12-20
ZA743023B (en) 1975-05-28
CH606002A5 (es) 1978-10-13
DE2423058A1 (de) 1974-12-12
DE2423058C2 (de) 1982-06-24
JPS5035395A (es) 1975-04-04

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