ES425107A1 - Benzodiazepines - Google Patents
BenzodiazepinesInfo
- Publication number
- ES425107A1 ES425107A1 ES425107A ES425107A ES425107A1 ES 425107 A1 ES425107 A1 ES 425107A1 ES 425107 A ES425107 A ES 425107A ES 425107 A ES425107 A ES 425107A ES 425107 A1 ES425107 A1 ES 425107A1
- Authority
- ES
- Spain
- Prior art keywords
- group
- radicals
- substituted
- optionally
- carbon atoms
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/12—1,5-Benzodiazepines; Hydrogenated 1,5-benzodiazepines
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Procedure for the preparation of new 5-aryl (or heteroaryl) -5-hydroxy-1H-1,5-benzodiazepin-2,4- (3H, 5H) -diones, characterized and documented in the specification, of the general formula ** (See formula) ** where R1 means a hydrogen atom, a straight chain or branched alcohol group with 1 to 4 carbon atoms, which may optionally be substituted in the omega position by a hydroxy group, the allyl group or the cyclopropylmethyl group, R2 means a radical phenyl, which may optionally be substituted by a halogen atom, a trifluoromethyl group or a nitro group, or a pyridyl radical, and R3 means a fluorine, chlorine or bromine atom or the trifluoromethyl or nitro group, characterized in that it is subjected to moderate oxidation to a compound of the general formula ** (See formula) ** where the radicals R1, R2 and R3 have the meanings indicated above and the radicals R, which may be the same or different, mean hydrogen atoms or straight or branched chain alcohol groups preferably with 1 to 4 carbon atoms; preferably by potassium permanganate or chromic acid at low temperatures. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19712103745 DE2103745A1 (en) | 1971-01-27 | 1971-01-27 | New 5-AryJ- (or Heteroaryl) -3-hydroxylH-1,5-benzodiazepine-2,4- (3H, 5H) -diones and processes for their preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES425107A1 true ES425107A1 (en) | 1976-07-01 |
Family
ID=5797047
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES399169A Expired ES399169A1 (en) | 1971-01-27 | 1972-01-25 | Benzodiazepines |
| ES425107A Expired ES425107A1 (en) | 1971-01-27 | 1974-04-08 | Benzodiazepines |
| ES425108A Expired ES425108A1 (en) | 1971-01-27 | 1974-04-08 | Benzodiazepines |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES399169A Expired ES399169A1 (en) | 1971-01-27 | 1972-01-25 | Benzodiazepines |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES425108A Expired ES425108A1 (en) | 1971-01-27 | 1974-04-08 | Benzodiazepines |
Country Status (19)
| Country | Link |
|---|---|
| AT (3) | AT315864B (en) |
| AU (1) | AU464682B2 (en) |
| BE (1) | BE778542A (en) |
| BG (3) | BG19174A3 (en) |
| CA (1) | CA967957A (en) |
| DD (1) | DD99376A5 (en) |
| DE (1) | DE2103745A1 (en) |
| DK (1) | DK130411B (en) |
| ES (3) | ES399169A1 (en) |
| FR (1) | FR2123474B1 (en) |
| GB (1) | GB1374529A (en) |
| HU (1) | HU164575B (en) |
| IE (1) | IE36035B1 (en) |
| IL (1) | IL38643A (en) |
| NL (1) | NL7201048A (en) |
| PL (3) | PL84620B1 (en) |
| RO (3) | RO60492A (en) |
| SU (3) | SU465791A3 (en) |
| ZA (1) | ZA72538B (en) |
-
1971
- 1971-01-27 DE DE19712103745 patent/DE2103745A1/en active Pending
-
1972
- 1972-01-14 RO RO71244A patent/RO60492A/ro unknown
- 1972-01-14 RO RO71243A patent/RO60491A/ro unknown
- 1972-01-14 RO RO69392A patent/RO61669A/ro unknown
- 1972-01-24 SU SU1740811A patent/SU465791A3/en active
- 1972-01-24 SU SU1926941A patent/SU493971A3/en active
- 1972-01-25 BG BG019569A patent/BG19174A3/en unknown
- 1972-01-25 BG BG021123A patent/BG21031A3/en unknown
- 1972-01-25 BG BG021122A patent/BG19176A3/en unknown
- 1972-01-25 HU HUBO1347A patent/HU164575B/hu unknown
- 1972-01-25 ES ES399169A patent/ES399169A1/en not_active Expired
- 1972-01-26 AU AU38362/72A patent/AU464682B2/en not_active Expired
- 1972-01-26 PL PL1972153120A patent/PL84620B1/pl unknown
- 1972-01-26 PL PL1972175546A patent/PL91875B1/pl unknown
- 1972-01-26 DD DD160513A patent/DD99376A5/xx unknown
- 1972-01-26 GB GB371972A patent/GB1374529A/en not_active Expired
- 1972-01-26 IL IL38643A patent/IL38643A/en unknown
- 1972-01-26 BE BE778542A patent/BE778542A/en unknown
- 1972-01-26 ZA ZA720538A patent/ZA72538B/en unknown
- 1972-01-26 DK DK34672AA patent/DK130411B/en unknown
- 1972-01-26 AT AT611173A patent/AT315864B/en not_active IP Right Cessation
- 1972-01-26 AT AT611273A patent/AT316566B/en not_active IP Right Cessation
- 1972-01-26 AT AT60972A patent/AT315849B/en not_active IP Right Cessation
- 1972-01-26 PL PL1972175545A patent/PL84243B1/pl unknown
- 1972-01-26 NL NL7201048A patent/NL7201048A/xx unknown
- 1972-01-27 FR FR7202739A patent/FR2123474B1/fr not_active Expired
- 1972-01-27 IE IE111/72A patent/IE36035B1/en unknown
- 1972-01-27 CA CA133,282A patent/CA967957A/en not_active Expired
-
1973
- 1973-01-24 SU SU1926940A patent/SU460627A3/en active
-
1974
- 1974-04-08 ES ES425107A patent/ES425107A1/en not_active Expired
- 1974-04-08 ES ES425108A patent/ES425108A1/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| ES425108A1 (en) | 1976-07-01 |
| BG19176A3 (en) | 1975-04-30 |
| NL7201048A (en) | 1972-07-31 |
| AT315864B (en) | 1974-06-10 |
| SU465791A3 (en) | 1975-03-30 |
| IE36035B1 (en) | 1976-08-04 |
| PL84243B1 (en) | 1976-03-31 |
| DE2103745A1 (en) | 1972-08-10 |
| IE36035L (en) | 1972-07-27 |
| RO60491A (en) | 1976-06-15 |
| RO61669A (en) | 1976-11-15 |
| DK130411C (en) | 1975-07-21 |
| AU3836272A (en) | 1973-08-02 |
| AT316566B (en) | 1974-07-25 |
| PL84620B1 (en) | 1976-04-30 |
| CA967957A (en) | 1975-05-20 |
| ZA72538B (en) | 1973-09-26 |
| AT315849B (en) | 1974-06-10 |
| BE778542A (en) | 1972-07-26 |
| HU164575B (en) | 1974-03-28 |
| SU493971A3 (en) | 1975-11-28 |
| GB1374529A (en) | 1974-11-20 |
| DK130411B (en) | 1975-02-17 |
| FR2123474B1 (en) | 1975-10-10 |
| ES399169A1 (en) | 1975-06-01 |
| BG21031A3 (en) | 1976-01-20 |
| FR2123474A1 (en) | 1972-09-08 |
| DD99376A5 (en) | 1973-08-05 |
| AU464682B2 (en) | 1975-08-20 |
| PL91875B1 (en) | 1977-03-31 |
| IL38643A (en) | 1976-01-30 |
| BG19174A3 (en) | 1975-04-30 |
| IL38643A0 (en) | 1972-03-28 |
| SU460627A3 (en) | 1975-02-15 |
| RO60492A (en) | 1976-06-15 |
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