ES425108A1 - Benzodiazepines - Google Patents
BenzodiazepinesInfo
- Publication number
- ES425108A1 ES425108A1 ES425108A ES425108A ES425108A1 ES 425108 A1 ES425108 A1 ES 425108A1 ES 425108 A ES425108 A ES 425108A ES 425108 A ES425108 A ES 425108A ES 425108 A1 ES425108 A1 ES 425108A1
- Authority
- ES
- Spain
- Prior art keywords
- group
- substituted
- optionally
- indicated above
- trifluoromethyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/12—1,5-Benzodiazepines; Hydrogenated 1,5-benzodiazepines
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Procedure for the preparation of new 5-aryl (or heteroaryl) -3-hydroxy-1H-1,5-benzodiazepin-2,4- (3H, 5H) -diones, characterized and documented in the specification of the general formula **(See formula)** where R1 means a hydrogen atom, a straight chain or branched alcohol group with 1 to 4 carbon atoms, which may optionally be substituted in the omega position by a hydroxy group, the allyl group or the cyclopropylmethyl group, R2 means a radical phenyl, which may optionally be substituted by a halogen atom, a trifluoromethyl group or a nitro group, or a pyridyl radical, and R3 means a fluorine, chlorine or bromine atom or the trifluoromethyl or nitro group, characterized in that it is put into usual boiling a compound of the general formula **(See formula)** in which the radicals R2 and R3 have the meanings indicated above and R1 have the meanings indicated above with the exception of hydrogen, preferably in the presence of an inert solvent and small amounts of copper powder or copper salts. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19712103745 DE2103745A1 (en) | 1971-01-27 | 1971-01-27 | New 5-AryJ- (or Heteroaryl) -3-hydroxylH-1,5-benzodiazepine-2,4- (3H, 5H) -diones and processes for their preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES425108A1 true ES425108A1 (en) | 1976-07-01 |
Family
ID=5797047
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES399169A Expired ES399169A1 (en) | 1971-01-27 | 1972-01-25 | Benzodiazepines |
| ES425108A Expired ES425108A1 (en) | 1971-01-27 | 1974-04-08 | Benzodiazepines |
| ES425107A Expired ES425107A1 (en) | 1971-01-27 | 1974-04-08 | Benzodiazepines |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES399169A Expired ES399169A1 (en) | 1971-01-27 | 1972-01-25 | Benzodiazepines |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES425107A Expired ES425107A1 (en) | 1971-01-27 | 1974-04-08 | Benzodiazepines |
Country Status (19)
| Country | Link |
|---|---|
| AT (3) | AT315849B (en) |
| AU (1) | AU464682B2 (en) |
| BE (1) | BE778542A (en) |
| BG (3) | BG19174A3 (en) |
| CA (1) | CA967957A (en) |
| DD (1) | DD99376A5 (en) |
| DE (1) | DE2103745A1 (en) |
| DK (1) | DK130411B (en) |
| ES (3) | ES399169A1 (en) |
| FR (1) | FR2123474B1 (en) |
| GB (1) | GB1374529A (en) |
| HU (1) | HU164575B (en) |
| IE (1) | IE36035B1 (en) |
| IL (1) | IL38643A (en) |
| NL (1) | NL7201048A (en) |
| PL (3) | PL84620B1 (en) |
| RO (3) | RO60491A (en) |
| SU (3) | SU493971A3 (en) |
| ZA (1) | ZA72538B (en) |
-
1971
- 1971-01-27 DE DE19712103745 patent/DE2103745A1/en active Pending
-
1972
- 1972-01-14 RO RO71243A patent/RO60491A/ro unknown
- 1972-01-14 RO RO71244A patent/RO60492A/ro unknown
- 1972-01-14 RO RO69392A patent/RO61669A/ro unknown
- 1972-01-24 SU SU1926941A patent/SU493971A3/en active
- 1972-01-24 SU SU1740811A patent/SU465791A3/en active
- 1972-01-25 ES ES399169A patent/ES399169A1/en not_active Expired
- 1972-01-25 HU HUBO1347A patent/HU164575B/hu unknown
- 1972-01-25 BG BG019569A patent/BG19174A3/en unknown
- 1972-01-25 BG BG021122A patent/BG19176A3/en unknown
- 1972-01-25 BG BG021123A patent/BG21031A3/en unknown
- 1972-01-26 PL PL1972153120A patent/PL84620B1/pl unknown
- 1972-01-26 GB GB371972A patent/GB1374529A/en not_active Expired
- 1972-01-26 NL NL7201048A patent/NL7201048A/xx unknown
- 1972-01-26 ZA ZA720538A patent/ZA72538B/en unknown
- 1972-01-26 AT AT60972A patent/AT315849B/en not_active IP Right Cessation
- 1972-01-26 IL IL38643A patent/IL38643A/en unknown
- 1972-01-26 DD DD160513A patent/DD99376A5/xx unknown
- 1972-01-26 PL PL1972175546A patent/PL91875B1/pl unknown
- 1972-01-26 PL PL1972175545A patent/PL84243B1/pl unknown
- 1972-01-26 AU AU38362/72A patent/AU464682B2/en not_active Expired
- 1972-01-26 DK DK34672AA patent/DK130411B/en unknown
- 1972-01-26 AT AT611273A patent/AT316566B/en not_active IP Right Cessation
- 1972-01-26 BE BE778542A patent/BE778542A/en unknown
- 1972-01-26 AT AT611173A patent/AT315864B/en not_active IP Right Cessation
- 1972-01-27 CA CA133,282A patent/CA967957A/en not_active Expired
- 1972-01-27 IE IE111/72A patent/IE36035B1/en unknown
- 1972-01-27 FR FR7202739A patent/FR2123474B1/fr not_active Expired
-
1973
- 1973-01-24 SU SU1926940A patent/SU460627A3/en active
-
1974
- 1974-04-08 ES ES425108A patent/ES425108A1/en not_active Expired
- 1974-04-08 ES ES425107A patent/ES425107A1/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| AU3836272A (en) | 1973-08-02 |
| ZA72538B (en) | 1973-09-26 |
| SU493971A3 (en) | 1975-11-28 |
| GB1374529A (en) | 1974-11-20 |
| CA967957A (en) | 1975-05-20 |
| IE36035L (en) | 1972-07-27 |
| SU460627A3 (en) | 1975-02-15 |
| RO60491A (en) | 1976-06-15 |
| PL91875B1 (en) | 1977-03-31 |
| AT316566B (en) | 1974-07-25 |
| ES399169A1 (en) | 1975-06-01 |
| AT315849B (en) | 1974-06-10 |
| BG19174A3 (en) | 1975-04-30 |
| DD99376A5 (en) | 1973-08-05 |
| RO61669A (en) | 1976-11-15 |
| FR2123474A1 (en) | 1972-09-08 |
| ES425107A1 (en) | 1976-07-01 |
| BG21031A3 (en) | 1976-01-20 |
| PL84620B1 (en) | 1976-04-30 |
| AU464682B2 (en) | 1975-08-20 |
| DE2103745A1 (en) | 1972-08-10 |
| IE36035B1 (en) | 1976-08-04 |
| RO60492A (en) | 1976-06-15 |
| FR2123474B1 (en) | 1975-10-10 |
| DK130411B (en) | 1975-02-17 |
| SU465791A3 (en) | 1975-03-30 |
| AT315864B (en) | 1974-06-10 |
| IL38643A0 (en) | 1972-03-28 |
| BG19176A3 (en) | 1975-04-30 |
| DK130411C (en) | 1975-07-21 |
| NL7201048A (en) | 1972-07-31 |
| PL84243B1 (en) | 1976-03-31 |
| IL38643A (en) | 1976-01-30 |
| BE778542A (en) | 1972-07-26 |
| HU164575B (en) | 1974-03-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES385627A2 (en) | Procedure for the preparation of morpholine derivatives. (Machine-translation by Google Translate, not legally binding) | |
| ES425108A1 (en) | Benzodiazepines | |
| ES423232A1 (en) | 2-phenylamino-imidazolines-(2) | |
| ES419019A1 (en) | Indolo-2,3-c quinolinone derivatives | |
| ES385634A1 (en) | 2-(n-cycloalkyl-phenylamino)-2-imidazolines-(2) and salts thereof | |
| ES419739A1 (en) | 2-aryl-amino-imidazoline-2 compounds | |
| ES421092A1 (en) | Azabenzo-1,5-diazepines | |
| ES454657A1 (en) | Triaryl or diarylpyridyl methanes | |
| ES368946A1 (en) | Quinazoline derivatives | |
| ES332954A1 (en) | A procedure for the preparation of heterociclic compounds. (Machine-translation by Google Translate, not legally binding) | |
| ES401130A1 (en) | New procedure for the preparation of 1-acil-5-phenyl-1H-1,5-benzodiazepin-2, 4- (3h, 5h) -dionas. (Machine-translation by Google Translate, not legally binding) | |
| ES286808A1 (en) | A procedure for the preparation of benzoxazepin derivatives (Machine-translation by Google Translate, not legally binding) | |
| ES298318A1 (en) | Procedure for the preparation of quinazolone compounds (Machine-translation by Google Translate, not legally binding) | |
| ES423146A1 (en) | Procedure for the preparation of new 2-alcohilmercapto-5-phenyl- 4h-3,5-benzodiazepin-4-onas. (Machine-translation by Google Translate, not legally binding) | |
| ES320300A1 (en) | A procedure for the preparation of quinazoline derivatives. (Machine-translation by Google Translate, not legally binding) | |
| ES451291A1 (en) | A procedure for the preparation of tienotiacin derivatives. (Machine-translation by Google Translate, not legally binding) | |
| ES369347A1 (en) | Procedure for the production of new 5-aril-1H-1,5-benzodiazepin-2,4- (3h-5h) -dionas. (Machine-translation by Google Translate, not legally binding) | |
| ES387029A1 (en) | Procedure for the obtaining of quinazolinone derivatives. (Machine-translation by Google Translate, not legally binding) | |
| ES472157A1 (en) | Procedure for the preparation of 10- (8-dialkylamine) propylamine phenotyazines. (Machine-translation by Google Translate, not legally binding) | |
| ES404877A1 (en) | Procedure for the production of 5-phenyl-1, 3, 4, 4a, 5, 9b-hexahidro-2H-indeno (1,2-c) pyridines. (Machine-translation by Google Translate, not legally binding) | |
| ES321313A1 (en) | Procedure for the preparation of biphenyl-4-substitute-4-amino-terciary-alcoxy. (Machine-translation by Google Translate, not legally binding) | |
| ES409194A1 (en) | Procedure for the obtaining of quinazolinone derivatives. (Machine-translation by Google Translate, not legally binding) | |
| ES396873A1 (en) | Procedure for the obtaining of pyridacine derivatives. (Machine-translation by Google Translate, not legally binding) | |
| ES367957A1 (en) | A procedure for the preparation of benzodiacepine derivatives. (Machine-translation by Google Translate, not legally binding) | |
| ES388200A1 (en) | Procedure for the preparation of substitute 5-aril-1H-1,5-benzo-diazepin-2,4 (3h, 5h) - dionas. (Machine-translation by Google Translate, not legally binding) |