ES417332A1 - Procedure for the preparation of trialcoxibenzoilpeptidos. (Machine-translation by Google Translate, not legally binding) - Google Patents
Procedure for the preparation of trialcoxibenzoilpeptidos. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES417332A1 ES417332A1 ES417332A ES417332A ES417332A1 ES 417332 A1 ES417332 A1 ES 417332A1 ES 417332 A ES417332 A ES 417332A ES 417332 A ES417332 A ES 417332A ES 417332 A1 ES417332 A1 ES 417332A1
- Authority
- ES
- Spain
- Prior art keywords
- group
- carbon atoms
- groups
- radicals
- general formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/0606—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing heteroatoms not provided for by C07K5/06086 - C07K5/06139, e.g. Ser, Met, Cys, Thr
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
- C07K5/0806—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Life Sciences & Earth Sciences (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Epoxy Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Procedure for the preparation of compounds of the general formula I **(See formula)** wherein the various A groups represent the same or different divalent radicals and mean straight or branched chain alcoholic groups with 2 to 11 carbon atoms or straight or branched chain alcoholicidene groups with 1 to 6 carbon atoms, which may also be substituted with a carboxy group, a hydroxy group, an alcoholmercapto group with 1 to 4 carbon atoms, an acylmercapto group with 1 to 6 carbon atoms, a phenyl radical, or an indolyl radical, the R4 radicals are also the same or different from each other y signify hydrogen or methyl groups, or else together with the adjoining member A in each case and the corresponding nitrogen atom can form a saturated five-membered ring, optionally containing an oxy group, X signifies a hydroxy group, an amino group or an alkoxy group with 1 to 4 carbon atoms, the radicals R1 to R3 are the same or different and are alcohol radicals with 1 to 3 carbon atoms and the m and n indices have the v values 0 or 1, and their salts, characterized in that an amino acid or a peptide of the general formula is reacted in a manner known per se. **(See formula)** where R4, A and X have the meanings indicated above and n'is 1, 2 or 3, with a derivative of an arylcarboxylic acid of the general formula **(See formula)** where m, R1, R2, R3, R4 and A have the meanings indicated above and n'' is 0, 1 or 2, the carboxyl group in the terminal position may also be activated or one or both carboxyl terminal groups may also be formulas II and III are part of a lactone ring, and eventually in the obtained compounds a lactone ring present is split and/or an esterified carboxy group is saponified, in a manner known per se, to form the carboxy group. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AT652272 | 1972-07-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES417332A1 true ES417332A1 (en) | 1976-03-01 |
Family
ID=3587161
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES417332A Expired ES417332A1 (en) | 1972-07-28 | 1973-07-27 | Procedure for the preparation of trialcoxibenzoilpeptidos. (Machine-translation by Google Translate, not legally binding) |
Country Status (9)
| Country | Link |
|---|---|
| JP (1) | JPS4943938A (en) |
| AU (1) | AU5834673A (en) |
| BE (1) | BE802929A (en) |
| DD (1) | DD107906A5 (en) |
| DE (1) | DE2338172A1 (en) |
| ES (1) | ES417332A1 (en) |
| FR (1) | FR2194424A1 (en) |
| NL (1) | NL7310453A (en) |
| ZA (1) | ZA735128B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4618539A (en) * | 1984-12-06 | 1986-10-21 | The Lubrizol Corporation | Corrosion-inhibiting compositions, and oil compositions containing said corrosion-inhibiting compositions |
-
1973
- 1973-07-11 FR FR7325424A patent/FR2194424A1/en not_active Withdrawn
- 1973-07-20 AU AU58346/73A patent/AU5834673A/en not_active Expired
- 1973-07-25 DD DD172516A patent/DD107906A5/xx unknown
- 1973-07-27 DE DE19732338172 patent/DE2338172A1/en active Pending
- 1973-07-27 NL NL7310453A patent/NL7310453A/xx unknown
- 1973-07-27 ZA ZA735128A patent/ZA735128B/en unknown
- 1973-07-27 BE BE6044260A patent/BE802929A/en unknown
- 1973-07-27 ES ES417332A patent/ES417332A1/en not_active Expired
- 1973-07-27 JP JP48084823A patent/JPS4943938A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| BE802929A (en) | 1974-01-28 |
| NL7310453A (en) | 1974-01-30 |
| DD107906A5 (en) | 1974-08-20 |
| ZA735128B (en) | 1974-06-26 |
| JPS4943938A (en) | 1974-04-25 |
| FR2194424A1 (en) | 1974-03-01 |
| AU5834673A (en) | 1975-01-23 |
| DE2338172A1 (en) | 1974-02-07 |
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