ES407265A1 - Procedure for the preparation of new derivatives of pregnanic acid (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for the preparation of new derivatives of pregnanic acid (Machine-translation by Google Translate, not legally binding)

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Publication number
ES407265A1
ES407265A1 ES0407265A ES407265A ES407265A1 ES 407265 A1 ES407265 A1 ES 407265A1 ES 0407265 A ES0407265 A ES 0407265A ES 407265 A ES407265 A ES 407265A ES 407265 A1 ES407265 A1 ES 407265A1
Authority
ES
Spain
Prior art keywords
signifies
formula
group
hydrogen atom
hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES0407265A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering AG filed Critical Schering AG
Priority to ES0407265A priority Critical patent/ES407265A1/en
Publication of ES407265A1 publication Critical patent/ES407265A1/en
Expired legal-status Critical Current

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Abstract

Procedure for the preparation of new pregnanic acid derivatives of the general formula I **(See formula)** with the substituent OR2 in the αf or βf position where -AB- signifies the -CH2-CH2-, -CH = CH- or -CC1 = CH- groupings, R1 signifies a hydrogen atom or a methyl group, R2 signifies an atom of hydrogen or an acyl group, R3 signifies a hydrogen atom or an optionally substituted hydrocarbon radical, or R2 and R3 together signify a dialkylmethylene or cycloalkylidene group, X signifies a hydrogen atom, a halogen atom or a methyl group, Y means a hydrogen atom or a halogen atom and Z means a hydroxy group or a halogen atom with atomic weight equal to or less than that of Y, and wherein at least one of the groups X, Y or R1 represents a different substituent from hydrogen, characterized in that a) 21-hydroxysteroids of the general formula II are reacted **(See formula)** wherein -AB-, X, Y, Z and R1 have the same meanings as in formula I, with an alcohol in the presence of divalent copper salts, or b) are transposed by treatment with strong bases compounds of the general formula III **(See formula)** where -A-B-, X, Y, Z and R1 have the same meanings as in formula I and Q means the groupings **(See formula)** and R4 signifies an alcoholic group and R5 signifies an acyl group, and if desired, in a manner known per se, ester groups present are saponified and/or esterified or condensed with ketones free 20-hydroxy groups and/or groups 21 -acid. (Machine-translation by Google Translate, not legally binding)
ES0407265A 1972-10-03 1972-10-03 Procedure for the preparation of new derivatives of pregnanic acid (Machine-translation by Google Translate, not legally binding) Expired ES407265A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES0407265A ES407265A1 (en) 1972-10-03 1972-10-03 Procedure for the preparation of new derivatives of pregnanic acid (Machine-translation by Google Translate, not legally binding)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES0407265A ES407265A1 (en) 1972-10-03 1972-10-03 Procedure for the preparation of new derivatives of pregnanic acid (Machine-translation by Google Translate, not legally binding)

Publications (1)

Publication Number Publication Date
ES407265A1 true ES407265A1 (en) 1975-10-16

Family

ID=59033525

Family Applications (1)

Application Number Title Priority Date Filing Date
ES0407265A Expired ES407265A1 (en) 1972-10-03 1972-10-03 Procedure for the preparation of new derivatives of pregnanic acid (Machine-translation by Google Translate, not legally binding)

Country Status (1)

Country Link
ES (1) ES407265A1 (en)

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