ES416614A1 - Procedimiento de preparacion de (benzoil-2et-1'-il)-1-(ci- namil-4''-piperazin-1''-il-metil)-2-bencimidazoles. - Google Patents
Procedimiento de preparacion de (benzoil-2et-1'-il)-1-(ci- namil-4''-piperazin-1''-il-metil)-2-bencimidazoles.Info
- Publication number
- ES416614A1 ES416614A1 ES416614A ES416614A ES416614A1 ES 416614 A1 ES416614 A1 ES 416614A1 ES 416614 A ES416614 A ES 416614A ES 416614 A ES416614 A ES 416614A ES 416614 A1 ES416614 A1 ES 416614A1
- Authority
- ES
- Spain
- Prior art keywords
- methyl
- novel
- benzimidazoles
- cinnamyl
- eth
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 title abstract 2
- 101100513046 Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) eth-1 gene Proteins 0.000 title 1
- 150000001556 benzimidazoles Chemical class 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
- 208000001953 Hypotension Diseases 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 230000001078 anti-cholinergic effect Effects 0.000 abstract 1
- 230000002686 anti-diuretic effect Effects 0.000 abstract 1
- 230000001262 anti-secretory effect Effects 0.000 abstract 1
- 230000000767 anti-ulcer Effects 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 239000000812 cholinergic antagonist Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000002496 gastric effect Effects 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 208000021822 hypotensive Diseases 0.000 abstract 1
- 230000001077 hypotensive effect Effects 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 230000002048 spasmolytic effect Effects 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
- 230000000304 vasodilatating effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/14—Radicals substituted by nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7224544A FR2190439B1 (enExample) | 1972-07-06 | 1972-07-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES416614A1 true ES416614A1 (es) | 1976-02-01 |
Family
ID=9101469
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES416614A Expired ES416614A1 (es) | 1972-07-06 | 1973-07-05 | Procedimiento de preparacion de (benzoil-2et-1'-il)-1-(ci- namil-4''-piperazin-1''-il-metil)-2-bencimidazoles. |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US3862177A (enExample) |
| JP (1) | JPS5434754B2 (enExample) |
| AU (1) | AU470009B2 (enExample) |
| BE (1) | BE801533A (enExample) |
| CA (1) | CA1001623A (enExample) |
| CH (1) | CH568313A5 (enExample) |
| DE (1) | DE2333831C3 (enExample) |
| ES (1) | ES416614A1 (enExample) |
| FR (1) | FR2190439B1 (enExample) |
| GB (1) | GB1374406A (enExample) |
| IT (1) | IT1055533B (enExample) |
| LU (1) | LU67903A1 (enExample) |
| NL (1) | NL7309435A (enExample) |
| SE (1) | SE403289B (enExample) |
| SU (1) | SU480217A3 (enExample) |
| ZA (1) | ZA734460B (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2291755A2 (fr) * | 1974-11-21 | 1976-06-18 | Delalande Sa | Nouveaux benzoyl-2' eth-1' yl)-1 (cinnamyl-4'' piperazin-1'' yl methyl)-2 benzimidazoles, leur procede de preparation et leur application en therapeutique |
| FR2297045A1 (fr) * | 1975-01-10 | 1976-08-06 | Delalande Sa | Nouveaux (aroyl-2' eth-1' yl)-1 (acetamido-4'' piperazin-1'' yl methyl)-2 benzimidazoles a proprietes antisecretoire gastrique et antiulcereuse |
| GB1487128A (en) * | 1975-01-10 | 1977-09-28 | Delalande Sa | 1-(2'-aroyl ethyl)2-(4"-carbamoyl-methyl-piperazin-1"-yl methyl)benzimidazoles their therapeutical applications and method for their preparation |
| JPS5540576Y2 (enExample) * | 1976-01-30 | 1980-09-22 | ||
| JPS5640032Y2 (enExample) * | 1976-12-20 | 1981-09-18 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1440565A (fr) * | 1964-07-23 | 1966-05-27 | Schering Ag | Nouveaux benzimidazoles substitués et leur préparation |
| US3362956A (en) * | 1965-08-19 | 1968-01-09 | Sterling Drug Inc | 1-[(heterocyclyl)-lower-alkyl]-4-substituted-piperazines |
-
1972
- 1972-07-06 FR FR7224544A patent/FR2190439B1/fr not_active Expired
-
1973
- 1973-06-27 BE BE132796A patent/BE801533A/xx unknown
- 1973-06-28 GB GB3084973A patent/GB1374406A/en not_active Expired
- 1973-06-29 LU LU67903A patent/LU67903A1/xx unknown
- 1973-07-02 US US376135A patent/US3862177A/en not_active Expired - Lifetime
- 1973-07-02 ZA ZA734460A patent/ZA734460B/xx unknown
- 1973-07-03 DE DE2333831A patent/DE2333831C3/de not_active Expired
- 1973-07-04 SE SE7309437A patent/SE403289B/xx unknown
- 1973-07-05 SU SU1936090A patent/SU480217A3/ru active
- 1973-07-05 CA CA175,719A patent/CA1001623A/en not_active Expired
- 1973-07-05 NL NL7309435A patent/NL7309435A/xx not_active Application Discontinuation
- 1973-07-05 JP JP7535273A patent/JPS5434754B2/ja not_active Expired
- 1973-07-05 ES ES416614A patent/ES416614A1/es not_active Expired
- 1973-07-05 AU AU57753/73A patent/AU470009B2/en not_active Expired
- 1973-07-06 CH CH990573A patent/CH568313A5/xx not_active IP Right Cessation
- 1973-07-06 IT IT69017/73A patent/IT1055533B/it active
Also Published As
| Publication number | Publication date |
|---|---|
| GB1374406A (en) | 1974-11-20 |
| ZA734460B (en) | 1974-06-26 |
| FR2190439B1 (enExample) | 1975-06-20 |
| DE2333831C3 (de) | 1979-04-26 |
| AU5775373A (en) | 1975-01-09 |
| IT1055533B (it) | 1982-01-11 |
| AU470009B2 (en) | 1976-02-26 |
| JPS5434754B2 (enExample) | 1979-10-29 |
| CA1001623A (en) | 1976-12-14 |
| LU67903A1 (enExample) | 1974-01-04 |
| NL7309435A (enExample) | 1974-01-08 |
| CH568313A5 (enExample) | 1975-10-31 |
| BE801533A (fr) | 1973-12-27 |
| DE2333831B2 (de) | 1978-07-27 |
| FR2190439A1 (enExample) | 1974-02-01 |
| US3862177A (en) | 1975-01-21 |
| SU480217A3 (ru) | 1975-08-05 |
| JPS4942684A (enExample) | 1974-04-22 |
| DE2333831A1 (de) | 1974-01-17 |
| SE403289B (sv) | 1978-08-07 |
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