ES415167A1 - Imidazo-isoindoles and phthalimidines - Google Patents

Imidazo-isoindoles and phthalimidines

Info

Publication number
ES415167A1
ES415167A1 ES415167A ES415167A ES415167A1 ES 415167 A1 ES415167 A1 ES 415167A1 ES 415167 A ES415167 A ES 415167A ES 415167 A ES415167 A ES 415167A ES 415167 A1 ES415167 A1 ES 415167A1
Authority
ES
Spain
Prior art keywords
formula
chlorine
hydrogen
signifies
carbon atoms
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES415167A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of ES415167A1 publication Critical patent/ES415167A1/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Indole Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Procedure for obtaining 3-hydroxyphthalimidine derivatives, of formula I, **(See formula)** wherein each of R and R1 which may be the same or different, signifies a hydrogen, chlorine or fluorine atom, and R2 signifies an alkyl radical of 1 to 5 carbon atoms, or a radical of formula III, **(See formula)** wherein each of R3 and R4, which may be the same or different, means a hydrogen, chlorine, or bromine atom, or a straight-chain alkyl radical containing 1 to 3 carbon atoms, with the proviso that when each one of R3 and R4 has a meaning other than a hydrogen atom, at least one of R3 and R4 is in a position other than an ortho position of the phenyl ring, characterized in that a compound of formula IV is reacted, **(See formula)** where R and R1 have the meanings indicated above, and X means a chlorine or bromine atom, with a compound of formula V, H2NCH2CH2NHSO2R2 V wherein R2 has the meaning indicated above, in an organic solvent that is inert under the reaction conditions, preferably at a temperature of from about 20º to about 60ºC, more preferably from 40º to 50ºC. (Machine-translation by Google Translate, not legally binding)
ES415167A 1970-04-28 1973-05-25 Imidazo-isoindoles and phthalimidines Expired ES415167A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US3277270A 1970-04-28 1970-04-28
US9250370A 1970-11-24 1970-11-24
US11588471A 1971-02-16 1971-02-16

Publications (1)

Publication Number Publication Date
ES415167A1 true ES415167A1 (en) 1976-05-16

Family

ID=27364216

Family Applications (2)

Application Number Title Priority Date Filing Date
ES390610A Expired ES390610A1 (en) 1970-04-28 1971-04-26 Imidazo-isoindoles and phthalimidines
ES415167A Expired ES415167A1 (en) 1970-04-28 1973-05-25 Imidazo-isoindoles and phthalimidines

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES390610A Expired ES390610A1 (en) 1970-04-28 1971-04-26 Imidazo-isoindoles and phthalimidines

Country Status (15)

Country Link
AT (1) AT323729B (en)
BE (1) BE766294A (en)
CA (1) CA952114A (en)
CH (1) CH548406A (en)
CS (1) CS181208B2 (en)
DD (1) DD96944A5 (en)
DE (1) DE2120263A1 (en)
ES (2) ES390610A1 (en)
FI (1) FI52727C (en)
FR (2) FR2086411B1 (en)
GB (1) GB1355074A (en)
NL (1) NL7105665A (en)
NO (1) NO132098C (en)
SU (1) SU442598A3 (en)
YU (1) YU34697B (en)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3454592A (en) * 1963-12-18 1969-07-08 Sandoz Ag 2-(omega-hydroxyalkyl)-3-hydroxy-3-phenylisoindolones

Also Published As

Publication number Publication date
NO132098B (en) 1975-06-09
YU103671A (en) 1979-07-10
AT323729B (en) 1975-07-25
CA952114A (en) 1974-07-30
FR2086411A1 (en) 1971-12-31
DD96944A5 (en) 1973-04-12
FR2120188B1 (en) 1977-12-23
GB1355074A (en) 1974-06-05
DE2120263A1 (en) 1971-11-18
FI52727C (en) 1977-11-10
CS181208B2 (en) 1978-03-31
CH548406A (en) 1974-04-30
FI52727B (en) 1977-08-01
NL7105665A (en) 1971-11-01
YU34697B (en) 1979-12-31
BE766294A (en) 1971-10-26
SU442598A3 (en) 1974-09-05
ES390610A1 (en) 1974-06-16
FR2086411B1 (en) 1973-06-08
FR2120188A1 (en) 1972-08-11
NO132098C (en) 1975-09-17

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