GB1355074A - Imidazo-isoindoles and phthalimidines - Google Patents

Imidazo-isoindoles and phthalimidines

Info

Publication number
GB1355074A
GB1355074A GB1133471A GB1133471A GB1355074A GB 1355074 A GB1355074 A GB 1355074A GB 1133471 A GB1133471 A GB 1133471A GB 1133471 A GB1133471 A GB 1133471A GB 1355074 A GB1355074 A GB 1355074A
Authority
GB
United Kingdom
Prior art keywords
general formula
chlorine
hydrogen
april
isoindoles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1133471A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of GB1355074A publication Critical patent/GB1355074A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)

Abstract

1355074 Isoindoline derivatives SANDOZ Ltd 26 April 1971 [28 April 1970 24 Nov 1970 16 Feb 1971] 11334/71 Heading C2C Novel isoindoline derivatives of the general formula wherein each of R and R 1 is a hydrogen, chlorine or fluorine atom and R 2 is a C 1-5 alkyl group or a group of formula in which each of R 3 and R 4 is a hydrogen, chlorine or bromine atom or a C 1-3 straightchain alkyl group, provided that when each of R 3 and R 4 is other than a hydrogen atom, at least one of them is in a position other than the o-position of the phenyl ring, are prepared by reaction of an o-benzoyl-benzoic acid halide of the general formula wherein X is a chlorine or bromine atom, with a sulphonamide of the general formula in an inert organic solvent, and may be converted to 2,3-dihydro-5H-imidazo[2,1-a]isoindoles of the general formula which have appetite-depressant and central nervous system stimulant activity, by treatment with 85-100 wt. per cent sulphuric or phosphoric acid. Reference has been directed by the Comptroller to Specifications 1,225,411, 1,225,412 and 1,225,413 also to Specification 1,325,066.
GB1133471A 1970-04-28 1971-04-26 Imidazo-isoindoles and phthalimidines Expired GB1355074A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US3277270A 1970-04-28 1970-04-28
US9250370A 1970-11-24 1970-11-24
US11588471A 1971-02-16 1971-02-16

Publications (1)

Publication Number Publication Date
GB1355074A true GB1355074A (en) 1974-06-05

Family

ID=27364216

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1133471A Expired GB1355074A (en) 1970-04-28 1971-04-26 Imidazo-isoindoles and phthalimidines

Country Status (14)

Country Link
AT (1) AT323729B (en)
BE (1) BE766294A (en)
CA (1) CA952114A (en)
CH (1) CH548406A (en)
CS (1) CS181208B2 (en)
DD (1) DD96944A5 (en)
DE (1) DE2120263A1 (en)
ES (2) ES390610A1 (en)
FI (1) FI52727C (en)
FR (2) FR2086411B1 (en)
GB (1) GB1355074A (en)
NL (1) NL7105665A (en)
NO (1) NO132098C (en)
YU (1) YU34697B (en)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3454592A (en) * 1963-12-18 1969-07-08 Sandoz Ag 2-(omega-hydroxyalkyl)-3-hydroxy-3-phenylisoindolones

Also Published As

Publication number Publication date
BE766294A (en) 1971-10-26
YU103671A (en) 1979-07-10
DE2120263A1 (en) 1971-11-18
NO132098B (en) 1975-06-09
FR2120188B1 (en) 1977-12-23
ES390610A1 (en) 1974-06-16
AT323729B (en) 1975-07-25
ES415167A1 (en) 1976-05-16
NL7105665A (en) 1971-11-01
DD96944A5 (en) 1973-04-12
NO132098C (en) 1975-09-17
CA952114A (en) 1974-07-30
SU442598A3 (en) 1974-09-05
FI52727C (en) 1977-11-10
YU34697B (en) 1979-12-31
FR2120188A1 (en) 1972-08-11
FI52727B (en) 1977-08-01
CH548406A (en) 1974-04-30
FR2086411A1 (en) 1971-12-31
CS181208B2 (en) 1978-03-31
FR2086411B1 (en) 1973-06-08

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee