ES438596A1 - Procedure for obtaining derivatives of benzocicloheptatiofeno. (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for obtaining derivatives of benzocicloheptatiofeno. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES438596A1
ES438596A1 ES438596A ES438596A ES438596A1 ES 438596 A1 ES438596 A1 ES 438596A1 ES 438596 A ES438596 A ES 438596A ES 438596 A ES438596 A ES 438596A ES 438596 A1 ES438596 A1 ES 438596A1
Authority
ES
Spain
Prior art keywords
translation
procedure
machine
legally binding
google translate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES438596A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of ES438596A1 publication Critical patent/ES438596A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/08—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing alicyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Procedure for obtaining benzocycloheptathiophene derivatives of formula I, **(See formula)** where R1 is hydrogen, chlorine, bromine or alkoxy of 1 to 4 carbon atoms and is in position 6 or 7 of the benzocycloheptathiophene nucleus, R2 is alkyl of 1 to 4 carbon atoms; benzyl; fluoro-, chloro- or bromo-substituted benzyl; diphenylmethyl; or fluoro-, chloro- or bromo-substituted diphenylmethyl, and/or one of a and a is hydroxyiminomethylene and the other is methylene, characterized in that a compound of formula II is reacted, **(See formula)** where R1 and R2 have the meanings indicated above, and the oxo group is in position 9 or 10 of the benzocycloheptathiophene nucleus, with hydroxylamine, preferably in an inert organic solvent, preferably at room temperature and at reflux temperature. (Machine-translation by Google Translate, not legally binding)
ES438596A 1972-01-24 1975-06-16 Procedure for obtaining derivatives of benzocicloheptatiofeno. (Machine-translation by Google Translate, not legally binding) Expired ES438596A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH98872A CH565172A5 (en) 1972-01-24 1972-01-24 4-piperidylidene benzocycloheptathiophenes - - antihistamines and serotonin and acetyl choline inhibitors

Publications (1)

Publication Number Publication Date
ES438596A1 true ES438596A1 (en) 1977-09-01

Family

ID=4199855

Family Applications (1)

Application Number Title Priority Date Filing Date
ES438596A Expired ES438596A1 (en) 1972-01-24 1975-06-16 Procedure for obtaining derivatives of benzocicloheptatiofeno. (Machine-translation by Google Translate, not legally binding)

Country Status (6)

Country Link
CH (1) CH565172A5 (en)
CS (1) CS180000B2 (en)
DK (1) DK134405B (en)
ES (1) ES438596A1 (en)
PL (1) PL92124B1 (en)
SU (1) SU505364A3 (en)

Also Published As

Publication number Publication date
CS180000B2 (en) 1977-12-30
SU505364A3 (en) 1976-02-28
DK134405B (en) 1976-11-01
PL92124B1 (en) 1977-03-31
DK134405C (en) 1977-03-28
CH565172A5 (en) 1975-08-15

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