ES408184A1 - Un procedimiento para la preparacion de alcaloides del tipode la eburnamina. - Google Patents
Un procedimiento para la preparacion de alcaloides del tipode la eburnamina.Info
- Publication number
- ES408184A1 ES408184A1 ES408184A ES408184A ES408184A1 ES 408184 A1 ES408184 A1 ES 408184A1 ES 408184 A ES408184 A ES 408184A ES 408184 A ES408184 A ES 408184A ES 408184 A1 ES408184 A1 ES 408184A1
- Authority
- ES
- Spain
- Prior art keywords
- salts
- group
- apovincamine
- alkali metal
- hydroxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- RXPRRQLKFXBCSJ-GIVPXCGWSA-N Vincamine Natural products C1=CC=C2C(CCN3CCC4)=C5[C@@H]3[C@]4(CC)C[C@](O)(C(=O)OC)N5C2=C1 RXPRRQLKFXBCSJ-GIVPXCGWSA-N 0.000 title 1
- RXPRRQLKFXBCSJ-UHFFFAOYSA-N dl-Vincamin Natural products C1=CC=C2C(CCN3CCC4)=C5C3C4(CC)CC(O)(C(=O)OC)N5C2=C1 RXPRRQLKFXBCSJ-UHFFFAOYSA-N 0.000 title 1
- 229960002726 vincamine Drugs 0.000 title 1
- 150000003839 salts Chemical class 0.000 abstract 5
- OZDNDGXASTWERN-CTNGQTDRSA-N Apovincamine Chemical compound C1=CC=C2C(CCN3CCC4)=C5[C@@H]3[C@]4(CC)C=C(C(=O)OC)N5C2=C1 OZDNDGXASTWERN-CTNGQTDRSA-N 0.000 abstract 2
- 229910052783 alkali metal Inorganic materials 0.000 abstract 2
- 150000001340 alkali metals Chemical class 0.000 abstract 2
- 229950006936 apovincamine Drugs 0.000 abstract 2
- OZDNDGXASTWERN-UHFFFAOYSA-N apovincamine Natural products C1=CC=C2C(CCN3CCC4)=C5C3C4(CC)C=C(C(=O)OC)N5C2=C1 OZDNDGXASTWERN-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- VLFDXKBCNKXRBE-YTQUADARSA-N (+)-Isoeburnamine Natural products O[C@@H]1n2c3c(c4c2[C@H]2[C@@](CC)(C1)CCC[N+]2CC4)cccc3 VLFDXKBCNKXRBE-YTQUADARSA-N 0.000 abstract 1
- 125000004454 (C1-C6) alkoxycarbonyl group Chemical group 0.000 abstract 1
- HONLKDDLTAZVQV-NZSAHSFTSA-N Eburnamine Chemical compound C1=CC=C2C(CCN3CCC4)=C5[C@H]3[C@@]4(CC)C[C@@H](O)N5C2=C1 HONLKDDLTAZVQV-NZSAHSFTSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 229930013930 alkaloid Natural products 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 239000002585 base Substances 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- HONLKDDLTAZVQV-UHFFFAOYSA-N eburnamine Natural products C1=CC=C2C(CCN3CCC4)=C5C3C4(CC)CC(O)N5C2=C1 HONLKDDLTAZVQV-UHFFFAOYSA-N 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D461/00—Heterocyclic compounds containing indolo [3,2,1-d,e] pyrido [3,2,1,j] [1,5]-naphthyridine ring systems, e.g. vincamine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HURI455A HU166474B (enrdf_load_stackoverflow) | 1971-11-03 | 1971-11-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES408184A1 true ES408184A1 (es) | 1975-11-01 |
Family
ID=11000881
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES408184A Expired ES408184A1 (es) | 1971-11-03 | 1972-11-02 | Un procedimiento para la preparacion de alcaloides del tipode la eburnamina. |
Country Status (23)
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU532001B2 (en) * | 1978-11-20 | 1983-09-15 | Sumitomo Chemical Company, Limited | Polycyclic indole derivatives |
| US4316028A (en) * | 1978-11-20 | 1982-02-16 | Sumitomo Chemical Company, Limited | Process for producing eburnane derivatives |
| HU187139B (en) * | 1982-06-30 | 1985-11-28 | Richter Gedeon Vegyeszet | Process for preparing new eburnan derivatives |
| EP3495361B1 (en) * | 2016-08-04 | 2020-10-28 | Harbin Pharmaceutical Group Co., Ltd. General Pharmaceutical Factory | Salt and crystal of diaza-benzofluorane compound |
-
1971
- 1971-11-03 HU HURI455A patent/HU166474B/hu unknown
-
1972
- 1972-10-16 CH CH1320575A patent/CH577504A5/xx not_active IP Right Cessation
- 1972-10-16 CH CH1510372A patent/CH586702A5/xx not_active IP Right Cessation
- 1972-10-16 CA CA153,943A patent/CA982585A/en not_active Expired
- 1972-10-17 ZA ZA727382A patent/ZA727382B/xx unknown
- 1972-10-17 NO NO3716/72A patent/NO136198C/no unknown
- 1972-10-19 BG BG021668A patent/BG20601A3/xx unknown
- 1972-10-19 IL IL40623A patent/IL40623A/xx unknown
- 1972-10-19 BG BG023693A patent/BG20379A3/xx unknown
- 1972-10-20 AU AU47984/72A patent/AU470084B2/en not_active Expired
- 1972-10-21 EG EG440/72A patent/EG10720A/xx active
- 1972-10-25 AT AT910372A patent/AT318823B/de not_active IP Right Cessation
- 1972-10-25 AT AT978773*7A patent/AT328624B/de not_active IP Right Cessation
- 1972-10-31 BE BE790842D patent/BE790842A/xx unknown
- 1972-10-31 DD DD166591A patent/DD101405A5/xx unknown
- 1972-10-31 FR FR7238529A patent/FR2158371B1/fr not_active Expired
- 1972-11-01 NL NL7214768A patent/NL7214768A/xx unknown
- 1972-11-01 JP JP47108965A patent/JPS515400B2/ja not_active Expired
- 1972-11-02 DE DE2253778A patent/DE2253778A1/de active Pending
- 1972-11-02 PL PL1972158592A patent/PL71069B1/pl unknown
- 1972-11-02 ES ES408184A patent/ES408184A1/es not_active Expired
- 1972-11-02 AR AR244942A patent/AR196498A1/es active
- 1972-11-02 SU SU1843735A patent/SU438183A3/ru active
- 1972-11-02 GB GB810074A patent/GB1402085A/en not_active Expired
- 1972-11-03 RO RO7200080514A patent/RO63053A/ro unknown
- 1972-11-03 RO RO72721A patent/RO62345A/ro unknown
-
1975
- 1975-07-25 SE SE7508516A patent/SE7508516L/xx not_active Application Discontinuation
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