GB1402085A - 15-hydroxy vincamine - Google Patents
15-hydroxy vincamineInfo
- Publication number
- GB1402085A GB1402085A GB810074A GB810074A GB1402085A GB 1402085 A GB1402085 A GB 1402085A GB 810074 A GB810074 A GB 810074A GB 810074 A GB810074 A GB 810074A GB 1402085 A GB1402085 A GB 1402085A
- Authority
- GB
- United Kingdom
- Prior art keywords
- nov
- active ingredients
- vincamine
- hydroxy
- hydroxyvincamine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- RXPRRQLKFXBCSJ-GIVPXCGWSA-N Vincamine Natural products C1=CC=C2C(CCN3CCC4)=C5[C@@H]3[C@]4(CC)C[C@](O)(C(=O)OC)N5C2=C1 RXPRRQLKFXBCSJ-GIVPXCGWSA-N 0.000 title 1
- RXPRRQLKFXBCSJ-UHFFFAOYSA-N dl-Vincamin Natural products C1=CC=C2C(CCN3CCC4)=C5C3C4(CC)CC(O)(C(=O)OC)N5C2=C1 RXPRRQLKFXBCSJ-UHFFFAOYSA-N 0.000 title 1
- 229960002726 vincamine Drugs 0.000 title 1
- 239000004480 active ingredient Substances 0.000 abstract 2
- DNXIKVLOVZVMQF-UHFFFAOYSA-N (3beta,16beta,17alpha,18beta,20alpha)-17-hydroxy-11-methoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]-yohimban-16-carboxylic acid, methyl ester Natural products C1C2CN3CCC(C4=CC=C(OC)C=C4N4)=C4C3CC2C(C(=O)OC)C(O)C1OC(=O)C1=CC(OC)=C(OC)C(OC)=C1 DNXIKVLOVZVMQF-UHFFFAOYSA-N 0.000 abstract 1
- 208000001953 Hypotension Diseases 0.000 abstract 1
- LCQMZZCPPSWADO-UHFFFAOYSA-N Reserpilin Natural products COC(=O)C1COCC2CN3CCc4c([nH]c5cc(OC)c(OC)cc45)C3CC12 LCQMZZCPPSWADO-UHFFFAOYSA-N 0.000 abstract 1
- QEVHRUUCFGRFIF-SFWBKIHZSA-N Reserpine Natural products O=C(OC)[C@@H]1[C@H](OC)[C@H](OC(=O)c2cc(OC)c(OC)c(OC)c2)C[C@H]2[C@@H]1C[C@H]1N(C2)CCc2c3c([nH]c12)cc(OC)cc3 QEVHRUUCFGRFIF-SFWBKIHZSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 229930013930 alkaloid Natural products 0.000 abstract 1
- 230000002490 cerebral effect Effects 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 208000021822 hypotensive Diseases 0.000 abstract 1
- 230000001077 hypotensive effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- BJOIZNZVOZKDIG-MDEJGZGSSA-N reserpine Chemical compound O([C@H]1[C@@H]([C@H]([C@H]2C[C@@H]3C4=C([C]5C=CC(OC)=CC5=N4)CCN3C[C@H]2C1)C(=O)OC)OC)C(=O)C1=CC(OC)=C(OC)C(OC)=C1 BJOIZNZVOZKDIG-MDEJGZGSSA-N 0.000 abstract 1
- 229960003147 reserpine Drugs 0.000 abstract 1
- MDMGHDFNKNZPAU-UHFFFAOYSA-N roserpine Natural products C1C2CN3CCC(C4=CC=C(OC)C=C4N4)=C4C3CC2C(OC(C)=O)C(OC)C1OC(=O)C1=CC(OC)=C(OC)C(OC)=C1 MDMGHDFNKNZPAU-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical group 0.000 abstract 1
- 239000003071 vasodilator agent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D461/00—Heterocyclic compounds containing indolo [3,2,1-d,e] pyrido [3,2,1,j] [1,5]-naphthyridine ring systems, e.g. vincamine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HURI455A HU166474B (enrdf_load_stackoverflow) | 1971-11-03 | 1971-11-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1402085A true GB1402085A (en) | 1975-08-06 |
Family
ID=11000881
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB810074A Expired GB1402085A (en) | 1971-11-03 | 1972-11-02 | 15-hydroxy vincamine |
Country Status (23)
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4316028A (en) * | 1978-11-20 | 1982-02-16 | Sumitomo Chemical Company, Limited | Process for producing eburnane derivatives |
| US4382936A (en) * | 1978-11-20 | 1983-05-10 | Sumitomo Chemical Company, Limited | Cerebral vasodilator eburnane derivatives |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU187139B (en) * | 1982-06-30 | 1985-11-28 | Richter Gedeon Vegyeszet | Process for preparing new eburnan derivatives |
| EP3495361B1 (en) * | 2016-08-04 | 2020-10-28 | Harbin Pharmaceutical Group Co., Ltd. General Pharmaceutical Factory | Salt and crystal of diaza-benzofluorane compound |
-
1971
- 1971-11-03 HU HURI455A patent/HU166474B/hu unknown
-
1972
- 1972-10-16 CH CH1320575A patent/CH577504A5/xx not_active IP Right Cessation
- 1972-10-16 CH CH1510372A patent/CH586702A5/xx not_active IP Right Cessation
- 1972-10-16 CA CA153,943A patent/CA982585A/en not_active Expired
- 1972-10-17 ZA ZA727382A patent/ZA727382B/xx unknown
- 1972-10-17 NO NO3716/72A patent/NO136198C/no unknown
- 1972-10-19 BG BG021668A patent/BG20601A3/xx unknown
- 1972-10-19 IL IL40623A patent/IL40623A/xx unknown
- 1972-10-19 BG BG023693A patent/BG20379A3/xx unknown
- 1972-10-20 AU AU47984/72A patent/AU470084B2/en not_active Expired
- 1972-10-21 EG EG440/72A patent/EG10720A/xx active
- 1972-10-25 AT AT910372A patent/AT318823B/de not_active IP Right Cessation
- 1972-10-25 AT AT978773*7A patent/AT328624B/de not_active IP Right Cessation
- 1972-10-31 BE BE790842D patent/BE790842A/xx unknown
- 1972-10-31 DD DD166591A patent/DD101405A5/xx unknown
- 1972-10-31 FR FR7238529A patent/FR2158371B1/fr not_active Expired
- 1972-11-01 NL NL7214768A patent/NL7214768A/xx unknown
- 1972-11-01 JP JP47108965A patent/JPS515400B2/ja not_active Expired
- 1972-11-02 DE DE2253778A patent/DE2253778A1/de active Pending
- 1972-11-02 PL PL1972158592A patent/PL71069B1/pl unknown
- 1972-11-02 ES ES408184A patent/ES408184A1/es not_active Expired
- 1972-11-02 AR AR244942A patent/AR196498A1/es active
- 1972-11-02 SU SU1843735A patent/SU438183A3/ru active
- 1972-11-02 GB GB810074A patent/GB1402085A/en not_active Expired
- 1972-11-03 RO RO7200080514A patent/RO63053A/ro unknown
- 1972-11-03 RO RO72721A patent/RO62345A/ro unknown
-
1975
- 1975-07-25 SE SE7508516A patent/SE7508516L/xx not_active Application Discontinuation
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4316028A (en) * | 1978-11-20 | 1982-02-16 | Sumitomo Chemical Company, Limited | Process for producing eburnane derivatives |
| US4382936A (en) * | 1978-11-20 | 1983-05-10 | Sumitomo Chemical Company, Limited | Cerebral vasodilator eburnane derivatives |
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] |