ES391633A1 - Un procedimiento para la preparacion de una 2,2-diaril-4- piperidinobutiramida. - Google Patents
Un procedimiento para la preparacion de una 2,2-diaril-4- piperidinobutiramida.Info
- Publication number
- ES391633A1 ES391633A1 ES391633A ES391633A ES391633A1 ES 391633 A1 ES391633 A1 ES 391633A1 ES 391633 A ES391633 A ES 391633A ES 391633 A ES391633 A ES 391633A ES 391633 A1 ES391633 A1 ES 391633A1
- Authority
- ES
- Spain
- Prior art keywords
- group
- member selected
- formula
- compound
- phenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001875 compounds Chemical class 0.000 abstract 6
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 5
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 3
- 239000002253 acid Substances 0.000 abstract 2
- 125000005059 halophenyl group Chemical group 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 150000001450 anions Chemical class 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 239000011541 reaction mixture Substances 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/32—Oxygen atoms
- C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/64—Acyl halides
- C07C57/76—Acyl halides containing halogen outside the carbonyl halide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/01—Saturated compounds having only one carboxyl group and containing hydroxy or O-metal groups
- C07C59/115—Saturated compounds having only one carboxyl group and containing hydroxy or O-metal groups containing halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/52—Oxygen atoms attached in position 4 having an aryl radical as the second substituent in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D211/74—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D211/78—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Apparatuses For Generation Of Mechanical Vibrations (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Furan Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4253070A | 1970-06-01 | 1970-06-01 | |
| US12960771A | 1971-03-30 | 1971-03-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES391633A1 true ES391633A1 (es) | 1975-09-16 |
Family
ID=26719340
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES391633A Expired ES391633A1 (es) | 1970-06-01 | 1971-05-27 | Un procedimiento para la preparacion de una 2,2-diaril-4- piperidinobutiramida. |
Country Status (18)
| Country | Link |
|---|---|
| JP (1) | JPS5754508B1 (cs) |
| AT (1) | AT312606B (cs) |
| BE (1) | BE767798A (cs) |
| CH (2) | CH553182A (cs) |
| CS (1) | CS171232B2 (cs) |
| DE (2) | DE2167193C2 (cs) |
| DK (1) | DK137382B (cs) |
| ES (1) | ES391633A1 (cs) |
| FI (1) | FI54472C (cs) |
| FR (1) | FR2100711B1 (cs) |
| GB (1) | GB1319040A (cs) |
| HK (1) | HK78076A (cs) |
| HU (1) | HU166420B (cs) |
| IL (1) | IL36949A (cs) |
| NL (1) | NL173848C (cs) |
| NO (1) | NO133547C (cs) |
| PL (1) | PL81548B1 (cs) |
| SE (1) | SE369418B (cs) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU675964B2 (en) * | 1992-08-05 | 1997-02-27 | John Wyeth & Brother Limited | Amide derivatives |
| US6190691B1 (en) | 1994-04-12 | 2001-02-20 | Adolor Corporation | Methods for treating inflammatory conditions |
| US5962477A (en) | 1994-04-12 | 1999-10-05 | Adolor Corporation | Screening methods for cytokine inhibitors |
| US5434158A (en) * | 1994-04-26 | 1995-07-18 | Merck & Co., Inc. | Spiro-substituted azacycles as neurokinin-3 antagonists |
| GB9502644D0 (en) * | 1995-02-10 | 1995-03-29 | Zeneca Ltd | Heterocyclic derivatives |
| US5849761A (en) | 1995-09-12 | 1998-12-15 | Regents Of The University Of California | Peripherally active anti-hyperalgesic opiates |
| US6573282B1 (en) | 1995-09-12 | 2003-06-03 | Adolor Corporation | Peripherally active anti-hyperalgesic opiates |
| AU1208397A (en) * | 1995-12-28 | 1997-07-28 | Takeda Chemical Industries Ltd. | Diphenylmethane derivatives as mip-1alpha/rantes receptor antagonists |
| EP2316468A1 (en) | 2002-02-22 | 2011-05-04 | Shire LLC | Delivery system and methods for protecting and administering dextroamphetamine |
| CN110357808A (zh) * | 2019-06-13 | 2019-10-22 | 上海上药新亚药业有限公司 | 一种盐酸洛哌丁胺的结晶工艺 |
-
1971
- 1971-05-18 NL NLAANVRAGE7106829,A patent/NL173848C/xx not_active IP Right Cessation
- 1971-05-25 GB GB1683971A patent/GB1319040A/en not_active Expired
- 1971-05-26 CH CH771871A patent/CH553182A/fr not_active IP Right Cessation
- 1971-05-26 CH CH605872A patent/CH549015A/fr not_active IP Right Cessation
- 1971-05-27 AT AT459271A patent/AT312606B/de not_active IP Right Cessation
- 1971-05-27 SE SE06863/71A patent/SE369418B/xx unknown
- 1971-05-27 ES ES391633A patent/ES391633A1/es not_active Expired
- 1971-05-28 FR FR7119640A patent/FR2100711B1/fr not_active Expired
- 1971-05-28 DE DE2167193A patent/DE2167193C2/de not_active Expired
- 1971-05-28 IL IL36949A patent/IL36949A/xx unknown
- 1971-05-28 BE BE767798A patent/BE767798A/xx not_active IP Right Cessation
- 1971-05-28 DE DE2126559A patent/DE2126559C3/de not_active Expired
- 1971-05-28 FI FI1497/71A patent/FI54472C/fi active
- 1971-05-28 DK DK259571AA patent/DK137382B/da unknown
- 1971-05-28 NO NO2024/71A patent/NO133547C/no unknown
- 1971-05-31 PL PL1971148508A patent/PL81548B1/pl unknown
- 1971-05-31 CS CS713975A patent/CS171232B2/cs unknown
- 1971-06-01 JP JP46038203A patent/JPS5754508B1/ja active Pending
- 1971-06-01 HU HUJA641A patent/HU166420B/hu unknown
-
1976
- 1976-12-09 HK HK780/76*UA patent/HK78076A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PL81548B1 (en) | 1975-08-30 |
| IL36949A (en) | 1974-07-31 |
| DE2126559C3 (de) | 1982-01-14 |
| BE767798A (fr) | 1971-11-29 |
| FR2100711B1 (cs) | 1974-09-27 |
| NO133547C (cs) | 1976-05-19 |
| FR2100711A1 (cs) | 1972-03-24 |
| IL36949A0 (en) | 1971-07-28 |
| HU166420B (cs) | 1975-03-28 |
| NL173848C (nl) | 1984-03-16 |
| HK78076A (en) | 1976-12-17 |
| NO133547B (cs) | 1976-02-09 |
| DE2126559A1 (de) | 1972-10-05 |
| CH549015A (fr) | 1974-05-15 |
| AT312606B (de) | 1974-01-10 |
| DE2167193C2 (de) | 1983-05-19 |
| SE369418B (cs) | 1974-08-26 |
| DK137382B (da) | 1978-02-27 |
| FI54472C (fi) | 1978-12-11 |
| CH553182A (fr) | 1974-08-30 |
| GB1319040A (en) | 1973-05-31 |
| NL7106829A (cs) | 1971-12-03 |
| DE2126559B2 (de) | 1981-02-26 |
| CS171232B2 (en) | 1976-10-31 |
| JPS5754508B1 (cs) | 1982-11-18 |
| DK137382C (cs) | 1978-08-07 |
| FI54472B (fi) | 1978-08-31 |
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