FI54472B - Foerfarande foer framstaellning av diarre foerhindrande och smaertstillande 2,2-diaryl-4-piperidinobutyramider och deras syraadditionsalter - Google Patents
Foerfarande foer framstaellning av diarre foerhindrande och smaertstillande 2,2-diaryl-4-piperidinobutyramider och deras syraadditionsalterInfo
- Publication number
- FI54472B FI54472B FI1497/71A FI149771A FI54472B FI 54472 B FI54472 B FI 54472B FI 1497/71 A FI1497/71 A FI 1497/71A FI 149771 A FI149771 A FI 149771A FI 54472 B FI54472 B FI 54472B
- Authority
- FI
- Finland
- Prior art keywords
- syraadditionsalter
- piperidinobutyramider
- overflower
- deras
- diaryl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/32—Oxygen atoms
- C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/64—Acyl halides
- C07C57/76—Acyl halides containing halogen outside the carbonyl halide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/01—Saturated compounds having only one carboxyl group and containing hydroxy or O-metal groups
- C07C59/115—Saturated compounds having only one carboxyl group and containing hydroxy or O-metal groups containing halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/52—Oxygen atoms attached in position 4 having an aryl radical as the second substituent in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D211/74—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D211/78—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Apparatuses For Generation Of Mechanical Vibrations (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FI762133A FI762133A (fi) | 1970-06-01 | 1976-07-26 |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US4253070A | 1970-06-01 | 1970-06-01 | |
US12960771A | 1971-03-30 | 1971-03-30 |
Publications (2)
Publication Number | Publication Date |
---|---|
FI54472B true FI54472B (fi) | 1978-08-31 |
FI54472C FI54472C (fi) | 1978-12-11 |
Family
ID=26719340
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI1497/71A FI54472C (fi) | 1970-06-01 | 1971-05-28 | Foerfarande foer framstaellning av diarre foerhindrande och smaertstillande 2,2-diaryl-4-piperidinobutyramider och deras syraadditionsalter |
Country Status (18)
Country | Link |
---|---|
JP (1) | JPS5754508B1 (fi) |
AT (1) | AT312606B (fi) |
BE (1) | BE767798A (fi) |
CH (2) | CH553182A (fi) |
CS (1) | CS171232B2 (fi) |
DE (2) | DE2167193C2 (fi) |
DK (1) | DK137382B (fi) |
ES (1) | ES391633A1 (fi) |
FI (1) | FI54472C (fi) |
FR (1) | FR2100711B1 (fi) |
GB (1) | GB1319040A (fi) |
HK (1) | HK78076A (fi) |
HU (1) | HU166420B (fi) |
IL (1) | IL36949A (fi) |
NL (1) | NL173848C (fi) |
NO (1) | NO133547C (fi) |
PL (1) | PL81548B1 (fi) |
SE (1) | SE369418B (fi) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU675964B2 (en) * | 1992-08-05 | 1997-02-27 | John Wyeth & Brother Limited | Amide derivatives |
US5962477A (en) | 1994-04-12 | 1999-10-05 | Adolor Corporation | Screening methods for cytokine inhibitors |
US6190691B1 (en) | 1994-04-12 | 2001-02-20 | Adolor Corporation | Methods for treating inflammatory conditions |
US5434158A (en) * | 1994-04-26 | 1995-07-18 | Merck & Co., Inc. | Spiro-substituted azacycles as neurokinin-3 antagonists |
GB9502644D0 (en) * | 1995-02-10 | 1995-03-29 | Zeneca Ltd | Heterocyclic derivatives |
US6573282B1 (en) | 1995-09-12 | 2003-06-03 | Adolor Corporation | Peripherally active anti-hyperalgesic opiates |
US5849761A (en) | 1995-09-12 | 1998-12-15 | Regents Of The University Of California | Peripherally active anti-hyperalgesic opiates |
WO1997024325A1 (en) * | 1995-12-28 | 1997-07-10 | Takeda Chemical Industries, Ltd. | DIPHENYLMETHANE DERIVATIVES AS MIP-1α/RANTES RECEPTOR ANTAGONISTS |
CN1649614A (zh) | 2002-02-22 | 2005-08-03 | 新河药品股份有限公司 | 活性剂传递系统和保护及施用活性剂的方法 |
CN110357808A (zh) * | 2019-06-13 | 2019-10-22 | 上海上药新亚药业有限公司 | 一种盐酸洛哌丁胺的结晶工艺 |
-
1971
- 1971-05-18 NL NLAANVRAGE7106829,A patent/NL173848C/xx not_active IP Right Cessation
- 1971-05-25 GB GB1683971A patent/GB1319040A/en not_active Expired
- 1971-05-26 CH CH771871A patent/CH553182A/fr not_active IP Right Cessation
- 1971-05-26 CH CH605872A patent/CH549015A/fr not_active IP Right Cessation
- 1971-05-27 AT AT459271A patent/AT312606B/de not_active IP Right Cessation
- 1971-05-27 ES ES391633A patent/ES391633A1/es not_active Expired
- 1971-05-27 SE SE06863/71A patent/SE369418B/xx unknown
- 1971-05-28 DK DK259571AA patent/DK137382B/da unknown
- 1971-05-28 NO NO2024/71A patent/NO133547C/no unknown
- 1971-05-28 FR FR7119640A patent/FR2100711B1/fr not_active Expired
- 1971-05-28 DE DE2167193A patent/DE2167193C2/de not_active Expired
- 1971-05-28 BE BE767798A patent/BE767798A/xx not_active IP Right Cessation
- 1971-05-28 FI FI1497/71A patent/FI54472C/fi active
- 1971-05-28 IL IL36949A patent/IL36949A/xx unknown
- 1971-05-28 DE DE2126559A patent/DE2126559C3/de not_active Expired
- 1971-05-31 CS CS713975A patent/CS171232B2/cs unknown
- 1971-05-31 PL PL1971148508A patent/PL81548B1/pl unknown
- 1971-06-01 HU HUJA641A patent/HU166420B/hu unknown
- 1971-06-01 JP JP46038203A patent/JPS5754508B1/ja active Pending
-
1976
- 1976-12-09 HK HK780/76*UA patent/HK78076A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
DK137382C (fi) | 1978-08-07 |
NL7106829A (fi) | 1971-12-03 |
ES391633A1 (es) | 1975-09-16 |
DK137382B (da) | 1978-02-27 |
FR2100711A1 (fi) | 1972-03-24 |
NO133547B (fi) | 1976-02-09 |
DE2126559B2 (de) | 1981-02-26 |
AT312606B (de) | 1974-01-10 |
DE2126559C3 (de) | 1982-01-14 |
IL36949A (en) | 1974-07-31 |
FR2100711B1 (fi) | 1974-09-27 |
NO133547C (fi) | 1976-05-19 |
HK78076A (en) | 1976-12-17 |
IL36949A0 (en) | 1971-07-28 |
GB1319040A (en) | 1973-05-31 |
DE2126559A1 (de) | 1972-10-05 |
NL173848C (nl) | 1984-03-16 |
JPS5754508B1 (fi) | 1982-11-18 |
SE369418B (fi) | 1974-08-26 |
CS171232B2 (en) | 1976-10-31 |
FI54472C (fi) | 1978-12-11 |
CH553182A (fr) | 1974-08-30 |
DE2167193C2 (de) | 1983-05-19 |
PL81548B1 (en) | 1975-08-30 |
HU166420B (fi) | 1975-03-28 |
BE767798A (fr) | 1971-11-29 |
CH549015A (fr) | 1974-05-15 |
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