ES385968A1 - Highly attenuated newcastle disease virus vaccine and production thereof - Google Patents

Highly attenuated newcastle disease virus vaccine and production thereof

Info

Publication number
ES385968A1
ES385968A1 ES385968A ES385968A ES385968A1 ES 385968 A1 ES385968 A1 ES 385968A1 ES 385968 A ES385968 A ES 385968A ES 385968 A ES385968 A ES 385968A ES 385968 A1 ES385968 A1 ES 385968A1
Authority
ES
Spain
Prior art keywords
virus
porcine
newcastle disease
chick embryo
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES385968A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of ES385968A1 publication Critical patent/ES385968A1/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/155—Paramyxoviridae, e.g. parainfluenza virus
    • A61K39/17—Newcastle disease virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5254—Virus avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18111—Avulavirus, e.g. Newcastle disease virus
    • C12N2760/18134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Abstract

A method of producing an attenuated Newcastle disease vaccine comprises: (1) cultivating Newcastle disease virus either by at least 20 serial passages in a porcine tissue culture or for at least 2 months in porcine stable cell lines to produce porcine cells containing attenuated virus, (2) inoculating this on to the chorioallantoic membrane of a chick embryo and cultivating the chick embryo and (3) recovering the virus from the resulting complex of chorioallantoic membrane and porcine cells and subjecting it to at least 2 serial passages in the allantoic cavity of a chick embryo. The procine tissue culture may contain primary kidney cells. Step (1) may be carried out by persistent infection of porcine stable cell lines with the virus. The virus recovered in step (3) may be further cultivated in a culture containing chick embryo cells to produce the vaccine.
ES385968A 1969-11-29 1970-11-27 Highly attenuated newcastle disease virus vaccine and production thereof Expired ES385968A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP9581969 1969-11-29

Publications (1)

Publication Number Publication Date
ES385968A1 true ES385968A1 (en) 1973-11-16

Family

ID=14148007

Family Applications (1)

Application Number Title Priority Date Filing Date
ES385968A Expired ES385968A1 (en) 1969-11-29 1970-11-27 Highly attenuated newcastle disease virus vaccine and production thereof

Country Status (7)

Country Link
CA (1) CA962593A (en)
DE (1) DE2058645C2 (en)
DK (1) DK124340B (en)
ES (1) ES385968A1 (en)
FR (1) FR2073436B1 (en)
GB (1) GB1274820A (en)
NL (1) NL170595C (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU826584A1 (en) * 1979-10-29 1982-11-07 Всесоюзный государственный научно-контрольный институт ветеринарных препаратов Vaccine against newcastle fowl disease, process for preparing the same and method for prophylaxis of newcastle fowl diease
HU197517B (en) * 1984-07-30 1989-04-28 Laszlo Csatary Process for production of terapeutical composition applicable against virus infection
US5124148A (en) * 1988-04-27 1992-06-23 United Cancer Research Institute Method for treating viral diseases with attenuated virus
US7914979B2 (en) 2004-11-05 2011-03-29 Wellstat Biologics Corporation Stable and filterable enveloped virus formulations
CN102268410B (en) * 2011-06-17 2013-02-27 湖北省农业科学院畜牧兽医研究所 Newcastle disease virus heat-resistant attenuated strain adapted to baby hamster kidney passage cell and preparation method and application thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2767117A (en) * 1953-10-22 1956-10-16 Crawley John Frederick Poultry virus vaccine products and method of preparing the same
GB1010509A (en) * 1962-02-23 1965-11-17 Pfizer Ltd Improvements in or relating to newcastle disease virus vaccines

Also Published As

Publication number Publication date
NL170595B (en) 1982-07-01
NL170595C (en) 1982-12-01
CA962593A (en) 1975-02-11
GB1274820A (en) 1972-05-17
FR2073436A1 (en) 1971-10-01
DE2058645C2 (en) 1982-02-11
DK124340B (en) 1972-10-09
FR2073436B1 (en) 1974-08-30
DE2058645A1 (en) 1971-06-09
NL7017334A (en) 1971-06-02

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