GB1274820A - Highly attenuated newcastle disease virus vaccine and production thereof - Google Patents

Highly attenuated newcastle disease virus vaccine and production thereof

Info

Publication number
GB1274820A
GB1274820A GB56463/70A GB5646370A GB1274820A GB 1274820 A GB1274820 A GB 1274820A GB 56463/70 A GB56463/70 A GB 56463/70A GB 5646370 A GB5646370 A GB 5646370A GB 1274820 A GB1274820 A GB 1274820A
Authority
GB
United Kingdom
Prior art keywords
virus
porcine
newcastle disease
chick embryo
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB56463/70A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of GB1274820A publication Critical patent/GB1274820A/en
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/155Paramyxoviridae, e.g. parainfluenza virus
    • A61K39/17Newcastle disease virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5254Virus avirulent or attenuated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/55Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552Veterinary vaccine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/18011Paramyxoviridae
    • C12N2760/18111Avulavirus, e.g. Newcastle disease virus
    • C12N2760/18134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Pulmonology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

1,274,820. Newcastle disease virus. TAKEDA YAKUHIN KOGYO K.K. 27 Nov., 1970 [29 Nov., 1969], No. 56463/70. Heading A5B. A method of producing an attenuated Newcastle disease vaccine comprises: (1) cultivating Newcastle disease virus either by at least 20 serial passages in a porcine tissue culture or for at least 2 months in porcine stable cell lines to produce porcine cells containing attenuated virus, (2) inoculating this on to the chorioallantoic membrane of a chick embryo and cultivating the chick embryo and (3) recovering the virus from the resulting complex of chorioallantoic membrane and porcine cells and subjecting it to at least 2 serial passages in the allantoic cavity of a chick embryo. The procine tissue culture may contain primary kidney cells. Step (1) may be carried out by persistent infection of porcine stable cell lines with the virus. The virus recovered in step (3) may be further cultivated in a culture containing chick embryo cells to produce the vaccine.
GB56463/70A 1969-11-29 1970-11-27 Highly attenuated newcastle disease virus vaccine and production thereof Expired GB1274820A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP9581969 1969-11-29

Publications (1)

Publication Number Publication Date
GB1274820A true GB1274820A (en) 1972-05-17

Family

ID=14148007

Family Applications (1)

Application Number Title Priority Date Filing Date
GB56463/70A Expired GB1274820A (en) 1969-11-29 1970-11-27 Highly attenuated newcastle disease virus vaccine and production thereof

Country Status (7)

Country Link
CA (1) CA962593A (en)
DE (1) DE2058645C2 (en)
DK (1) DK124340B (en)
ES (1) ES385968A1 (en)
FR (1) FR2073436B1 (en)
GB (1) GB1274820A (en)
NL (1) NL170595C (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986000811A1 (en) * 1984-07-30 1986-02-13 Csatary Laszlo Therapeutic preparations for treatment of certain viral and other diseases and the preparation of the same
US5124148A (en) * 1988-04-27 1992-06-23 United Cancer Research Institute Method for treating viral diseases with attenuated virus
US7914979B2 (en) 2004-11-05 2011-03-29 Wellstat Biologics Corporation Stable and filterable enveloped virus formulations

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU826584A1 (en) * 1979-10-29 1982-11-07 Всесоюзный государственный научно-контрольный институт ветеринарных препаратов Vaccine against newcastle fowl disease, process for preparing the same and method for prophylaxis of newcastle fowl diease
CN102268410B (en) * 2011-06-17 2013-02-27 湖北省农业科学院畜牧兽医研究所 Newcastle disease virus heat-resistant attenuated strain adapted to baby hamster kidney passage cell and preparation method and application thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2767117A (en) * 1953-10-22 1956-10-16 Crawley John Frederick Poultry virus vaccine products and method of preparing the same
GB1010509A (en) * 1962-02-23 1965-11-17 Pfizer Ltd Improvements in or relating to newcastle disease virus vaccines

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986000811A1 (en) * 1984-07-30 1986-02-13 Csatary Laszlo Therapeutic preparations for treatment of certain viral and other diseases and the preparation of the same
US5124148A (en) * 1988-04-27 1992-06-23 United Cancer Research Institute Method for treating viral diseases with attenuated virus
US7914979B2 (en) 2004-11-05 2011-03-29 Wellstat Biologics Corporation Stable and filterable enveloped virus formulations

Also Published As

Publication number Publication date
CA962593A (en) 1975-02-11
FR2073436B1 (en) 1974-08-30
ES385968A1 (en) 1973-11-16
FR2073436A1 (en) 1971-10-01
NL7017334A (en) 1971-06-02
DK124340B (en) 1972-10-09
NL170595C (en) 1982-12-01
DE2058645A1 (en) 1971-06-09
NL170595B (en) 1982-07-01
DE2058645C2 (en) 1982-02-11

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee