GB1010509A - Improvements in or relating to newcastle disease virus vaccines - Google Patents

Improvements in or relating to newcastle disease virus vaccines

Info

Publication number
GB1010509A
GB1010509A GB7111/62A GB711162A GB1010509A GB 1010509 A GB1010509 A GB 1010509A GB 7111/62 A GB7111/62 A GB 7111/62A GB 711162 A GB711162 A GB 711162A GB 1010509 A GB1010509 A GB 1010509A
Authority
GB
United Kingdom
Prior art keywords
tissue culture
virus
newcastle disease
disease virus
avian
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB7111/62A
Inventor
Nicholas Michael Larin
John Norman Pilfold
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Ltd
Original Assignee
Pfizer Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Ltd filed Critical Pfizer Ltd
Priority to GB7111/62A priority Critical patent/GB1010509A/en
Priority to BR147168/63A priority patent/BR6347168D0/en
Priority to DEP31192A priority patent/DE1179670B/en
Publication of GB1010509A publication Critical patent/GB1010509A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/155—Paramyxoviridae, e.g. parainfluenza virus
    • A61K39/17—Newcastle disease virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5254—Virus avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55516—Proteins; Peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18111—Avulavirus, e.g. Newcastle disease virus
    • C12N2760/18134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Pulmonology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Live Newcastle Disease virus vaccine is prepared by inoculating a non-avian tissue culture with a seed of an attenuated strain of Newcastle Disease virus, taken from avian tissue, cultivating the virus in the non-avian tissue culture and then harvesting the virus-containing fluid from the tissue culture before the appearance of a cytopathic effect in the tissue culture cells. The non-avian tissue culture used is preferably that obtained from the kidneys of monkeys, calves or pigs. The virus-containing fluid obtained may be mixed with a minor proportion by volume of bovine serum and/or skimmed milk and after adjusting, if necessary, the pH of the mixture so formed to approximately 7, protamine or clupeine sulphate is added and the resultant precipitate is harvested. This precipitate can be reconstituted to the desired concentration by admixture with a suitable diluent, e.g. physiologically-buffered saline solution.
GB7111/62A 1962-02-23 1962-02-23 Improvements in or relating to newcastle disease virus vaccines Expired GB1010509A (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
GB7111/62A GB1010509A (en) 1962-02-23 1962-02-23 Improvements in or relating to newcastle disease virus vaccines
BR147168/63A BR6347168D0 (en) 1962-02-23 1963-02-22 VACCINE PREPARATION
DEP31192A DE1179670B (en) 1962-02-23 1963-02-22 Process for making vaccine against Newcastle disease

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7111/62A GB1010509A (en) 1962-02-23 1962-02-23 Improvements in or relating to newcastle disease virus vaccines

Publications (1)

Publication Number Publication Date
GB1010509A true GB1010509A (en) 1965-11-17

Family

ID=9826810

Family Applications (1)

Application Number Title Priority Date Filing Date
GB7111/62A Expired GB1010509A (en) 1962-02-23 1962-02-23 Improvements in or relating to newcastle disease virus vaccines

Country Status (3)

Country Link
BR (1) BR6347168D0 (en)
DE (1) DE1179670B (en)
GB (1) GB1010509A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2058645A1 (en) * 1969-11-29 1971-06-09 Takeda Chemical Industries Ltd Process for the preparation of live attenuated Newcastle Disease Virus vaccine

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU826584A1 (en) * 1979-10-29 1982-11-07 Всесоюзный государственный научно-контрольный институт ветеринарных препаратов Vaccine against newcastle fowl disease, process for preparing the same and method for prophylaxis of newcastle fowl diease

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2058645A1 (en) * 1969-11-29 1971-06-09 Takeda Chemical Industries Ltd Process for the preparation of live attenuated Newcastle Disease Virus vaccine
FR2073436A1 (en) * 1969-11-29 1971-10-01 Takeda Chemical Industries Ltd

Also Published As

Publication number Publication date
BR6347168D0 (en) 1973-08-02
DE1179670B (en) 1964-10-15

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