ES385557A1 - 06-methyl-steroids and processes for their preparation - Google Patents

06-methyl-steroids and processes for their preparation

Info

Publication number
ES385557A1
ES385557A1 ES385557A ES385557A ES385557A1 ES 385557 A1 ES385557 A1 ES 385557A1 ES 385557 A ES385557 A ES 385557A ES 385557 A ES385557 A ES 385557A ES 385557 A1 ES385557 A1 ES 385557A1
Authority
ES
Spain
Prior art keywords
steroids
methyl
general formula
formula
hydroxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES385557A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Patent GmbH
Original Assignee
Merck Patent GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent GmbH filed Critical Merck Patent GmbH
Publication of ES385557A1 publication Critical patent/ES385557A1/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)

Abstract

Procedure for the preparation of 16-nethyl steroids of the general formula I **(See formula)** in which RO means an esterified or etherified hydroxy group and R1 means F, Cl, Br, CH3 or CF3 and where an additional double bond may optionally be present in position 6 (7), characterized in that a 3-hydroxy-l6-methyl-steroid of the general formula II **(See formula)** in which R1 has the indicated significance and where an additional double bond may eventually be present in position 6 (7), or a 3-position esterified derivative suitable for reaction of one of such 3-hydroxy-16-methyl-steroids is treated with an esterifying or etherifying agent of the general formula ROH in which R has the indicated significance, or with a derivative suitable for the reaction of one of such compounds or because in a steroid that otherwise corresponds to formula I, a functionally altered 20-preserve group is solvolitically released. (Machine-translation by Google Translate, not legally binding)
ES385557A 1969-11-15 1970-11-14 06-methyl-steroids and processes for their preparation Expired ES385557A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19691957473 DE1957473A1 (en) 1969-11-15 1969-11-15 16-methyl steroids and process for their preparation

Publications (1)

Publication Number Publication Date
ES385557A1 true ES385557A1 (en) 1973-03-16

Family

ID=5751167

Family Applications (1)

Application Number Title Priority Date Filing Date
ES385557A Expired ES385557A1 (en) 1969-11-15 1970-11-14 06-methyl-steroids and processes for their preparation

Country Status (17)

Country Link
JP (1) JPS501271B1 (en)
AT (2) AT313489B (en)
BE (1) BE758843A (en)
BR (1) BR6915400D0 (en)
CH (1) CH549561A (en)
CS (1) CS156510B2 (en)
DE (1) DE1957473A1 (en)
DK (1) DK131608C (en)
ES (1) ES385557A1 (en)
FR (1) FR2073362B1 (en)
GB (1) GB1282520A (en)
HU (1) HU162451B (en)
IL (1) IL35432A (en)
NL (1) NL7013989A (en)
PL (1) PL81132B1 (en)
SE (2) SE364707B (en)
ZA (1) ZA706463B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS54114684U (en) * 1978-01-28 1979-08-11
JPH0389670U (en) * 1989-12-29 1991-09-12

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1094258B (en) * 1959-02-17 1960-12-08 Merck Ag E Process for the preparation of fluorinated 16-methyl steroids

Also Published As

Publication number Publication date
FR2073362B1 (en) 1974-09-27
BE758843A (en) 1971-05-12
ZA706463B (en) 1971-05-27
FR2073362A1 (en) 1971-10-01
JPS501271B1 (en) 1975-01-16
SE378826B (en) 1975-09-15
DK131608B (en) 1975-08-11
IL35432A0 (en) 1971-04-28
AT324587B (en) 1975-09-10
DE1957473A1 (en) 1971-05-27
CS156510B2 (en) 1974-07-24
DK131608C (en) 1976-01-19
GB1282520A (en) 1972-07-19
PL81132B1 (en) 1975-08-30
HU162451B (en) 1973-02-28
CH549561A (en) 1974-05-31
SE364707B (en) 1974-03-04
NL7013989A (en) 1971-05-18
IL35432A (en) 1974-11-29
AT313489B (en) 1974-02-25
BR6915400D0 (en) 1973-03-13

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