ES385471A1 - Procedure for the preparation of new tertiary butanols basically replaced. (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for the preparation of new tertiary butanols basically replaced. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES385471A1
ES385471A1 ES385471A ES385471A ES385471A1 ES 385471 A1 ES385471 A1 ES 385471A1 ES 385471 A ES385471 A ES 385471A ES 385471 A ES385471 A ES 385471A ES 385471 A1 ES385471 A1 ES 385471A1
Authority
ES
Spain
Prior art keywords
phenyl
chlorine
hydroxy
translation
procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES385471A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH
Publication of ES385471A1 publication Critical patent/ES385471A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Procedure for the preparation of new basically substituted tertiary butanoles of the formula **(See formula)** where Hal means a chlorine or bromine atom; R1 signifies a hydrogen, chlorine or bromine atom; R2 and R3, which may be the same or different, mean straight or branched chain alcohol radicals, dialcoylaminoalcohilo, cycloalcohilo, phenyl, aralcohilo or adamantyl, one of the R2 or R3 radicals also being able to represent a hydrogen atom or together with the atom of Nitrogen means a pyrrolidine, piperidine, piperazine, morpholine, hexamethyleneimine or camfidine ring, optionally substituted by hydroxy, alkoxy, phenyl or lower alcohol groups; and R4 signifies a straight or branched chain alcohol radical, cycloalkyl, norbomyl, phenyl, aralkoxy, naphthyl, pyridyl or thienyl, a cyclohexyl radical substituted by hydroxy or lower alcohol groups or a phenyl radical substituted by hydroxy, alcoholic, alkoxy, alcoholylthio groups., trifluoromethyl, phenyl, phenoxy, by fluorine, chlorine or bromine atoms, as well as their physiologically compatible acid addition salts, characterized in that a compound of the general formula is halogenated in a solvent **(See formula)** wherein R1, R2, R3 and R4 are as defined above, and if desired a compound obtained of the general formula I is transformed into a salt, according to customary methods, with a physiologically compatible organic or inorganic acid. (Machine-translation by Google Translate, not legally binding)
ES385471A 1970-08-28 1970-11-12 Procedure for the preparation of new tertiary butanols basically replaced. (Machine-translation by Google Translate, not legally binding) Expired ES385471A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19702042750 DE2042750A1 (en) 1970-08-28 1970-08-28 Basic substd tert butanols; transquilising - anti emetic ulcer inhibitory

Publications (1)

Publication Number Publication Date
ES385471A1 true ES385471A1 (en) 1973-05-01

Family

ID=5780991

Family Applications (3)

Application Number Title Priority Date Filing Date
ES385473A Expired ES385473A1 (en) 1970-08-28 1970-11-12 Procedure for the preparation of new tertiary butanols basically replaced. (Machine-translation by Google Translate, not legally binding)
ES385471A Expired ES385471A1 (en) 1970-08-28 1970-11-12 Procedure for the preparation of new tertiary butanols basically replaced. (Machine-translation by Google Translate, not legally binding)
ES385472A Expired ES385472A1 (en) 1970-08-28 1970-11-12 Procedure for the preparation of new tertiary butanols basically replaced. (Machine-translation by Google Translate, not legally binding)

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES385473A Expired ES385473A1 (en) 1970-08-28 1970-11-12 Procedure for the preparation of new tertiary butanols basically replaced. (Machine-translation by Google Translate, not legally binding)

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES385472A Expired ES385472A1 (en) 1970-08-28 1970-11-12 Procedure for the preparation of new tertiary butanols basically replaced. (Machine-translation by Google Translate, not legally binding)

Country Status (9)

Country Link
KR (2) KR780000213B1 (en)
AT (3) AT308074B (en)
BG (2) BG17747A3 (en)
CS (2) CS168544B2 (en)
DE (1) DE2042750A1 (en)
ES (3) ES385473A1 (en)
PL (1) PL84543B1 (en)
RO (2) RO58297A (en)
SU (2) SU421179A3 (en)

Also Published As

Publication number Publication date
BG17747A3 (en) 1973-12-25
CS168544B2 (en) 1976-06-29
RO58297A (en) 1975-07-15
AT308074B (en) 1973-06-25
ES385472A1 (en) 1973-05-01
SU421179A3 (en) 1974-03-25
SU420170A3 (en) 1974-03-15
ES385473A1 (en) 1973-05-01
KR780000230B1 (en) 1978-07-01
PL84543B1 (en) 1976-04-30
CS168543B2 (en) 1976-06-29
BG17748A3 (en) 1973-12-25
RO59184A (en) 1976-02-15
DE2042750A1 (en) 1972-03-02
AT308073B (en) 1973-06-25
AT310723B (en) 1973-10-10
KR780000213B1 (en) 1978-06-12

Similar Documents

Publication Publication Date Title
ES431516A1 (en) Procedure for the preparation of 2- (heterdanilmetilo 5,9-beta-dialcohil-6,7- benzonortanos. (Machine-translation by Google Translate, not legally binding)
ES391299A1 (en) 2-(n-allyl-phenylamino)-imidazolines-(2)and salts thereof
ES413639A1 (en) Dopamine derivatives
ES336020A1 (en) Procedure for the preparation of new derivatives of imidazol. (Machine-translation by Google Translate, not legally binding)
ES387016A1 (en) Isoquinoline derivatives
ES467954A1 (en) Indoles
ES384182A1 (en) 1-(m-halo-p-amino-phenyl)-4-aminotert.butanols-(1)and salts thereof
ES385471A1 (en) Procedure for the preparation of new tertiary butanols basically replaced. (Machine-translation by Google Translate, not legally binding)
ES378466A1 (en) Novel aminopiperidines, processes for their preparation, and compositions incorporating them
ES385470A1 (en) Procedure for the preparation of new tertiary butanols basically replaced. (Machine-translation by Google Translate, not legally binding)
ES432789A1 (en) Procedure for the preparation of benzytamines. (Machine-translation by Google Translate, not legally binding)
ES296634A1 (en) Procedure for the production of new heterocyclic compounds (Machine-translation by Google Translate, not legally binding)
ES385774A1 (en) Procedure for the preparation of new 2- (5-nitro-2- furil) -the (3,2-d) pyrimidines. (Machine-translation by Google Translate, not legally binding)
ES452391A1 (en) Benzisothiazoline-1,1-dioxide derivatives, compositions and methods
ES412068A1 (en) Xylidides
ES410855A1 (en) Process for the production of benzocycloheptathiophenone derivative
ES406767A1 (en) Procedure for the preparation of new indol derivatives. (Machine-translation by Google Translate, not legally binding)
ES442612A1 (en) Isoquinoline compounds
ES378758A1 (en) Procedure for the preparation of new derivatives of isoquinolein. (Machine-translation by Google Translate, not legally binding)
ES354961A1 (en) A procedure for the preparation of new aminocetons. (Machine-translation by Google Translate, not legally binding)
ES421810A1 (en) Pyrimidopyrimidines
ES355977A1 (en) Procedure for the preparation of new amino-dibenzo (b, f) (1,4) -oxazepin- 11 (10 h) -onas. (Machine-translation by Google Translate, not legally binding)
ES387840A1 (en) 2-(2-imidazolin-2-ylthio)-acetanilides
ES402731A1 (en) Procedure for the preparation of derivatives of (alcoxy-4-piperidine-alcohil) -10-phenotyazine. (Machine-translation by Google Translate, not legally binding)
ES393339A1 (en) Naphthoquinone derivatives