ES372061A1 - 6,9,21-trihalogenosteroids - Google Patents

6,9,21-trihalogenosteroids

Info

Publication number
ES372061A1
ES372061A1 ES372061A ES372061A ES372061A1 ES 372061 A1 ES372061 A1 ES 372061A1 ES 372061 A ES372061 A ES 372061A ES 372061 A ES372061 A ES 372061A ES 372061 A1 ES372061 A1 ES 372061A1
Authority
ES
Spain
Prior art keywords
chlorine
formula
known per
manner known
fluorine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES372061A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19681801390 external-priority patent/DE1801390C3/en
Application filed by Schering AG filed Critical Schering AG
Publication of ES372061A1 publication Critical patent/ES372061A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Procedure for the preparation of new 6,9,21-trohalogen steroids of the formula ** (see formula) ** where X means a fluorine, chlorine or bromine atom and Y means a chlorine or fluorine atom, characterized in that, in a manner known per se, to the double bond at position 9,11 of a starting steroid of the general formula ** (see formula) ** Hypohalogenic acid HOX'is added, in which X' means a chlorine or bromine atom, and -in the event that in the last desired products X means a fluorine atom- the compound 9α-chloro- or 9α-bromo is transformed -11α-hydroxy, also in a manner known per se, in 9,11-epoxide, and finally the epoxy ring is opened with hydrogen fluoride. (Machine-translation by Google Translate, not legally binding)
ES372061A 1968-10-02 1969-09-30 6,9,21-trihalogenosteroids Expired ES372061A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19681801390 DE1801390C3 (en) 1968-10-02 6,9,21-trihalo steroids, processes for their preparation, medicaments containing them and 6,21-dihalo intermediates

Publications (1)

Publication Number Publication Date
ES372061A1 true ES372061A1 (en) 1971-09-01

Family

ID=5709719

Family Applications (1)

Application Number Title Priority Date Filing Date
ES372061A Expired ES372061A1 (en) 1968-10-02 1969-09-30 6,9,21-trihalogenosteroids

Country Status (16)

Country Link
AT (1) AT290033B (en)
BE (1) BE739736A (en)
BR (1) BR6912959D0 (en)
CH (1) CH540891A (en)
CS (1) CS150285B2 (en)
DK (1) DK121053B (en)
ES (1) ES372061A1 (en)
FI (1) FI46505C (en)
FR (1) FR2019676A1 (en)
GB (1) GB1286659A (en)
IE (1) IE33329B1 (en)
IL (1) IL33017A (en)
NL (1) NL167439C (en)
NO (1) NO130824C (en)
RO (1) RO54664A (en)
SE (1) SE352082B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2010458B2 (en) * 1970-02-28 1979-04-26 Schering Ag, 1000 Berlin Und 4619 Bergkamen New 21-Halogen Steroids

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3499016A (en) * 1958-08-04 1970-03-03 Upjohn Co 6alpha-fluoro-16alpha-methyl derivatives of the pregnane series

Also Published As

Publication number Publication date
GB1286659A (en) 1972-08-23
DE1801390A1 (en) 1970-05-21
NL167439B (en) 1981-07-16
NO130824B (en) 1974-11-11
IE33329L (en) 1970-04-02
FI46505B (en) 1973-01-02
DK121053B (en) 1971-08-30
IE33329B1 (en) 1974-05-29
IL33017A0 (en) 1969-11-30
RO54664A (en) 1973-03-15
BR6912959D0 (en) 1973-02-08
FR2019676A1 (en) 1970-07-03
NL6914942A (en) 1970-04-06
CS150285B2 (en) 1973-09-04
DE1801390B2 (en) 1977-02-17
NL167439C (en) 1981-12-16
CH540891A (en) 1973-08-31
AT290033B (en) 1971-05-10
SE352082B (en) 1972-12-18
NO130824C (en) 1975-02-19
IL33017A (en) 1974-01-14
FI46505C (en) 1973-04-10
BE739736A (en) 1970-04-02

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