ES366173A1 - Antacid composition - Google Patents

Antacid composition

Info

Publication number
ES366173A1
ES366173A1 ES366173A ES366173A ES366173A1 ES 366173 A1 ES366173 A1 ES 366173A1 ES 366173 A ES366173 A ES 366173A ES 366173 A ES366173 A ES 366173A ES 366173 A1 ES366173 A1 ES 366173A1
Authority
ES
Spain
Prior art keywords
antacid
composition
viscosity
gelation agent
gelation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES366173A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of ES366173A1 publication Critical patent/ES366173A1/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A61K33/08—Oxides; Hydroxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A61K33/10—Carbonates; Bicarbonates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A61K33/12—Magnesium silicate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/245—Bismuth; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

An antacid composition comprises an antacid and at least one pharmaceutically acceptable gelation agent which is a waterdispersible colloidal anionic ether and/or ester of a polymer of a monosaccharide, wherein the gelation agent and the antacid are selected and the proportion thereof are such that: (1) the composition contains a major proportion of antacid and a minor proportion of gelation agent based on the combined total weight of the antacid and gelation agent in the composition, (2) the composition, when prepared in aqueous suspension so as to attain a viscosity of 300 cps. at 25 C, must be capable of containing a greater total antacid-solids concentration than that attainable without inclusion of gelation agents, and, (3) upon the progressive addition of less than 2 cc. increments of phosphate solution, having the composition defined below, per 100 grams of an aqueous suspension of fluid consistency of the formulation meeting the criteria 1 and 2, an increase in viscosity to a viscosity greater than the initial viscosity of the suspension of fluid consistency is obtained, said phosphate solution prepared by dissolving 41.6 gm. of Na 3 PO 4 .12H 2 O and 55.3 gm. NaH 2 PO 4 .H 2 O is approximately 25 ml. of hot distilled water and diluting the resulting solution to a 100 ml. volume. The composition may also contain other therapeutic substances such as anti-spasmodics, e.g. dicyclomine hydrochloride or atropine sulphate sedatives tranquillizers anti-depressants or topical anaesthetics such as xylocaine.
ES366173A 1968-04-18 1969-04-17 Antacid composition Expired ES366173A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US72217668A 1968-04-18 1968-04-18
US78572768A 1968-12-20 1968-12-20

Publications (1)

Publication Number Publication Date
ES366173A1 true ES366173A1 (en) 1971-04-01

Family

ID=27110553

Family Applications (1)

Application Number Title Priority Date Filing Date
ES366173A Expired ES366173A1 (en) 1968-04-18 1969-04-17 Antacid composition

Country Status (15)

Country Link
JP (1) JPS4621672B1 (en)
AU (1) AU438147B2 (en)
BE (1) BE731695A (en)
CA (1) CA959760A (en)
CH (1) CH536114A (en)
DE (1) DE1919802A1 (en)
DK (1) DK127269B (en)
ES (1) ES366173A1 (en)
FI (1) FI50831C (en)
FR (1) FR2007475A1 (en)
GB (1) GB1269987A (en)
IL (1) IL32020A (en)
NL (1) NL6906087A (en)
NO (1) NO129077B (en)
SE (1) SE388356B (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1401257A (en) * 1972-06-30 1975-07-16 Miles Lab Process for preparing a spray dried calcium carbonate composition
GB1601833A (en) * 1978-02-06 1981-11-04 Wellcome Found Antacid formulation
SE7905972L (en) * 1979-07-09 1981-01-10 Haessle Ab PROCEDURE FOR THE PREPARATION OF Gastric Acid-Neutralizing Agents, Gastric Acid-Neutralizing Agents, AND METHOD OF TREATING HYPERACIDITY AND RELATED DISEASE CONDITIONS
SG72632A1 (en) * 1985-04-18 2000-05-23 Procter & Gamble Treatment of non-ulcer dyspepsia with bismuth salts
IT1215332B (en) * 1987-01-12 1990-02-08 Crinos Industria Farmaco PHARMACEUTICAL COMPOSITION CONTAINING SULGLICOTIDE FOR THERAPY OF GASTRIC ULCER
DE3812378A1 (en) * 1988-04-14 1989-10-26 Theo Mertens Mobile device for grinding and mixing harvested crops
US4980175A (en) * 1989-01-03 1990-12-25 Leonard Chavkin Liquid orally administrable compositions based on edible oils
US4988679A (en) * 1989-01-03 1991-01-29 Leonard Chavkin Liquid sustained release composition
DE4305919A1 (en) * 1993-02-26 1994-09-01 Ruediger Potthoff Transporting hopper for plastics granulate
WO2003066022A2 (en) * 2002-02-04 2003-08-14 Pharmacia Corporation Stable pharmaceutical composition useful for treating gastrointestinal disorders
WO2003074086A1 (en) * 2002-03-04 2003-09-12 Medrx Co., Ltd. Liquid matrix undergoing phase transfer in vivo and liquid oral preparations
US20030232092A1 (en) * 2002-06-14 2003-12-18 Hasenmayer Donald L. Liquid antacid compositions
US9486460B2 (en) 2014-04-29 2016-11-08 The Procter & Gamble Company Bismuth containing liquid pharmaceutical suspensions
MX370908B (en) 2014-04-29 2020-01-08 Procter & Gamble Method for making bismuth-containing liquid pharmaceutical suspensions.
CN114732828A (en) * 2022-04-27 2022-07-12 广西南宁百会药业集团有限公司 Hydrotalcite suspension and preparation method thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE621147A (en) *

Also Published As

Publication number Publication date
DK127269B (en) 1973-10-15
AU5353969A (en) 1970-10-22
FR2007475A1 (en) 1970-01-09
JPS4621672B1 (en) 1971-06-19
AU438147B2 (en) 1973-07-18
IL32020A0 (en) 1969-06-25
SE388356B (en) 1976-10-04
FI50831C (en) 1976-08-10
CH536114A (en) 1973-04-30
FI50831B (en) 1976-04-30
IL32020A (en) 1972-11-28
BE731695A (en) 1969-10-20
NO129077B (en) 1974-02-25
GB1269987A (en) 1972-04-12
NL6906087A (en) 1969-10-21
CA959760A (en) 1974-12-24
DE1919802A1 (en) 1969-11-06

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