GB1269987A - Antacid composition - Google Patents
Antacid compositionInfo
- Publication number
- GB1269987A GB1269987A GB09070/69A GB1907069A GB1269987A GB 1269987 A GB1269987 A GB 1269987A GB 09070/69 A GB09070/69 A GB 09070/69A GB 1907069 A GB1907069 A GB 1907069A GB 1269987 A GB1269987 A GB 1269987A
- Authority
- GB
- United Kingdom
- Prior art keywords
- antacid
- composition
- viscosity
- gelation agent
- gelation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
- A61K33/08—Oxides; Hydroxides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
- A61K33/10—Carbonates; Bicarbonates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
- A61K33/12—Magnesium silicate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/245—Bismuth; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
1,269,987. Antacid compositions. G. R. BROWN. 14 April, 1969 [18 April, 1968; 20 Dec., 1968], No. 19070/69. Heading A5B. An antacid composition comprises an antacid and at least one pharmaceutically acceptable gelation agent which is a waterdispersible colloidal anionic ether and/or ester of a polymer of a monosaccharide, wherein the gelation agent and the antacid are selected and the proportion thereof are such that: (1) the composition contains a major proportion of antacid and a minor proportion of gelation agent based on the combined total weight of the antacid and gelation agent in the composition, (2) the composition, when prepared in aqueous suspension so as to attain a viscosity of 300 cps. at 25C, must be capable of containing a greater total antacid-solids concentration than that attainable without inclusion of gelation agents, and, (3) upon the progressive addition of less than 2 cc. increments of phosphate solution, having the composition defined below, per 100 grams of an aqueous suspension of fluid consistency of the formulation meeting the criteria 1 and 2, an increase in viscosity to a viscosity greater than the initial viscosity of the suspension of fluid consistency is obtained, said phosphate solution prepared by dissolving 41.6 gm. of Na 3 PO 4 .12H 2 O and 55.3 gm. NaH 2 PO 4 .H 2 O is approximately 25 ml. of hot distilled water and diluting the resulting solution to a 100 ml. volume. The composition may also contain other therapeutic substances such as anti-spasmodics, e.g. dicyclomine hydrochloride or atropine sulphate; sedatives; tranquillizers; anti-depressants or topical anaesthetics such as xylocaine.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US72217668A | 1968-04-18 | 1968-04-18 | |
| US78572768A | 1968-12-20 | 1968-12-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1269987A true GB1269987A (en) | 1972-04-12 |
Family
ID=27110553
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB09070/69A Expired GB1269987A (en) | 1968-04-18 | 1969-04-14 | Antacid composition |
Country Status (15)
| Country | Link |
|---|---|
| JP (1) | JPS4621672B1 (en) |
| AU (1) | AU438147B2 (en) |
| BE (1) | BE731695A (en) |
| CA (1) | CA959760A (en) |
| CH (1) | CH536114A (en) |
| DE (1) | DE1919802A1 (en) |
| DK (1) | DK127269B (en) |
| ES (1) | ES366173A1 (en) |
| FI (1) | FI50831C (en) |
| FR (1) | FR2007475A1 (en) |
| GB (1) | GB1269987A (en) |
| IL (1) | IL32020A (en) |
| NL (1) | NL6906087A (en) |
| NO (1) | NO129077B (en) |
| SE (1) | SE388356B (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003066022A2 (en) * | 2002-02-04 | 2003-08-14 | Pharmacia Corporation | Stable pharmaceutical composition useful for treating gastrointestinal disorders |
| EP1374874A2 (en) * | 2002-06-14 | 2004-01-02 | McNEIL-PPC, INC. | Liquid antacid compositions |
| US9486436B2 (en) | 2014-04-29 | 2016-11-08 | The Procter & Gamble Company | Method for making bismuth containing liquid pharmaceutical suspensions |
| US9486460B2 (en) | 2014-04-29 | 2016-11-08 | The Procter & Gamble Company | Bismuth containing liquid pharmaceutical suspensions |
| CN114732828A (en) * | 2022-04-27 | 2022-07-12 | 广西南宁百会药业集团有限公司 | Hydrotalcite suspension and preparation method thereof |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1401256A (en) * | 1972-06-30 | 1975-07-16 | Miles Lab | Anticid tablet and preparation thereof |
| GB1601833A (en) * | 1978-02-06 | 1981-11-04 | Wellcome Found | Antacid formulation |
| SE7905972L (en) * | 1979-07-09 | 1981-01-10 | Haessle Ab | PROCEDURE FOR THE PREPARATION OF Gastric Acid-Neutralizing Agents, Gastric Acid-Neutralizing Agents, AND METHOD OF TREATING HYPERACIDITY AND RELATED DISEASE CONDITIONS |
| WO1986005981A1 (en) * | 1985-04-18 | 1986-10-23 | Borody Thomas J | Treatment of non-ulcer dyspepsia with bismuth salts |
| IT1215332B (en) * | 1987-01-12 | 1990-02-08 | Crinos Industria Farmaco | PHARMACEUTICAL COMPOSITION CONTAINING SULGLICOTIDE FOR THERAPY OF GASTRIC ULCER |
| DE3812378A1 (en) * | 1988-04-14 | 1989-10-26 | Theo Mertens | Mobile device for grinding and mixing harvested crops |
| US4988679A (en) * | 1989-01-03 | 1991-01-29 | Leonard Chavkin | Liquid sustained release composition |
| US4980175A (en) * | 1989-01-03 | 1990-12-25 | Leonard Chavkin | Liquid orally administrable compositions based on edible oils |
| DE4305919A1 (en) * | 1993-02-26 | 1994-09-01 | Ruediger Potthoff | Transporting hopper for plastics granulate |
| KR20040089628A (en) * | 2002-03-04 | 2004-10-21 | 가부시키가이샤 메드렉스 | Liquid matrix undergoing phase transfer in vivo and liquid oral preparations |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE621147A (en) * |
-
1969
- 1969-04-14 GB GB09070/69A patent/GB1269987A/en not_active Expired
- 1969-04-14 IL IL32020A patent/IL32020A/en unknown
- 1969-04-15 NO NO1526/69A patent/NO129077B/no unknown
- 1969-04-15 FI FI691089A patent/FI50831C/en active
- 1969-04-16 AU AU53539/69A patent/AU438147B2/en not_active Expired
- 1969-04-16 CA CA048,813A patent/CA959760A/en not_active Expired
- 1969-04-17 DK DK209369AA patent/DK127269B/en unknown
- 1969-04-17 ES ES366173A patent/ES366173A1/en not_active Expired
- 1969-04-18 FR FR6912182A patent/FR2007475A1/fr not_active Withdrawn
- 1969-04-18 DE DE19691919802 patent/DE1919802A1/en not_active Ceased
- 1969-04-18 CH CH593269A patent/CH536114A/en not_active IP Right Cessation
- 1969-04-18 SE SE6905549A patent/SE388356B/en unknown
- 1969-04-18 BE BE731695D patent/BE731695A/xx unknown
- 1969-04-18 NL NL6906087A patent/NL6906087A/xx unknown
- 1969-04-18 JP JP3015469A patent/JPS4621672B1/ja active Pending
Cited By (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003066022A2 (en) * | 2002-02-04 | 2003-08-14 | Pharmacia Corporation | Stable pharmaceutical composition useful for treating gastrointestinal disorders |
| WO2003066022A3 (en) * | 2002-02-04 | 2004-01-22 | Pharmacia Corp | Stable pharmaceutical composition useful for treating gastrointestinal disorders |
| US7135197B2 (en) | 2002-02-04 | 2006-11-14 | Pharmacia Corporation | Stable pharmaceutical composition useful for treating gastrointestinal disorders |
| EP1374874A2 (en) * | 2002-06-14 | 2004-01-02 | McNEIL-PPC, INC. | Liquid antacid compositions |
| EP1374874A3 (en) * | 2002-06-14 | 2004-01-07 | McNEIL-PPC, INC. | Liquid antacid compositions |
| AU2003204688B2 (en) * | 2002-06-14 | 2008-04-10 | Mcneil-Ppc, Inc. | Liquid antacid compositions |
| US9486436B2 (en) | 2014-04-29 | 2016-11-08 | The Procter & Gamble Company | Method for making bismuth containing liquid pharmaceutical suspensions |
| US9486460B2 (en) | 2014-04-29 | 2016-11-08 | The Procter & Gamble Company | Bismuth containing liquid pharmaceutical suspensions |
| US10034888B2 (en) | 2014-04-29 | 2018-07-31 | The Procter & Gamble Company | Method for making bismuth containing liquid pharmaceutical suspensions |
| US10039835B2 (en) | 2014-04-29 | 2018-08-07 | The Procter & Gamble Company | Bismuth containing liquid pharmaceutical suspensions |
| US10532063B2 (en) | 2014-04-29 | 2020-01-14 | The Procter & Gamble Company | Method for making bismuth containing liquid pharmaceutical suspensions |
| US10632200B2 (en) | 2014-04-29 | 2020-04-28 | The Procter & Gamble Company | Bismuth containing liquid pharmaceutical suspensions |
| CN114732828A (en) * | 2022-04-27 | 2022-07-12 | 广西南宁百会药业集团有限公司 | Hydrotalcite suspension and preparation method thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| AU438147B2 (en) | 1973-07-18 |
| DK127269B (en) | 1973-10-15 |
| FI50831C (en) | 1976-08-10 |
| BE731695A (en) | 1969-10-20 |
| SE388356B (en) | 1976-10-04 |
| FR2007475A1 (en) | 1970-01-09 |
| FI50831B (en) | 1976-04-30 |
| AU5353969A (en) | 1970-10-22 |
| IL32020A0 (en) | 1969-06-25 |
| CH536114A (en) | 1973-04-30 |
| JPS4621672B1 (en) | 1971-06-19 |
| DE1919802A1 (en) | 1969-11-06 |
| IL32020A (en) | 1972-11-28 |
| ES366173A1 (en) | 1971-04-01 |
| NO129077B (en) | 1974-02-25 |
| CA959760A (en) | 1974-12-24 |
| NL6906087A (en) | 1969-10-21 |
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