ES359159A1 - Procedimiento para la produccion de nuevos derivados de la piperazina. - Google Patents
Procedimiento para la produccion de nuevos derivados de la piperazina.Info
- Publication number
- ES359159A1 ES359159A1 ES359159A ES359159A ES359159A1 ES 359159 A1 ES359159 A1 ES 359159A1 ES 359159 A ES359159 A ES 359159A ES 359159 A ES359159 A ES 359159A ES 359159 A1 ES359159 A1 ES 359159A1
- Authority
- ES
- Spain
- Prior art keywords
- ring
- phenylpiperazines
- aryl
- salts
- lower alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
- C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
- C07D295/03—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
- C07D295/067—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents attached to the same carbon chain, which is not interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/092—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings with aromatic radicals attached to the chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
- C07D295/104—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/108—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE1966B0088772 DE1670144B2 (de) | 1966-09-03 | 1966-09-03 | Substituierte n- eckige klammer auf l-arylpropyl-(2) eckige klammer zu -n'- phenyl-piperazine, verfahren zu deren herstellung und daraus hergestellte zentraldepressiv wirkende pharmazeutische praeparate |
| DEB0093758 | 1967-08-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES359159A1 true ES359159A1 (es) | 1970-05-16 |
Family
ID=25968081
Family Applications (8)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES344693A Expired ES344693A1 (es) | 1966-09-03 | 1967-09-01 | Procedimiento para la produccion de nuevos derivados de la piperazina. |
| ES359161A Expired ES359161A1 (es) | 1966-09-03 | 1968-10-15 | Procedimiento para la produccion de nuevos derivados de la piperazina. |
| ES359158A Expired ES359158A1 (es) | 1966-09-03 | 1968-10-15 | Procedimiento para la produccion de nuevos derivados de la piperazina. |
| ES359160A Expired ES359160A1 (es) | 1966-09-03 | 1968-10-15 | Procedimiento para la produccion de nuevos derivados de la piperazina. |
| ES359157A Expired ES359157A1 (es) | 1966-09-03 | 1968-10-15 | Procedimiento para la produccion de nuevos derivados de la piperazina. |
| ES359159A Expired ES359159A1 (es) | 1966-09-03 | 1968-10-15 | Procedimiento para la produccion de nuevos derivados de la piperazina. |
| ES359156A Expired ES359156A1 (es) | 1966-09-03 | 1968-10-15 | Procedimiento para la produccion de nuevos derivados de la piperazina. |
| ES359162A Expired ES359162A1 (es) | 1966-09-03 | 1968-10-15 | Procedimiento para la produccion de nuevos derivados de la piperazina. |
Family Applications Before (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES344693A Expired ES344693A1 (es) | 1966-09-03 | 1967-09-01 | Procedimiento para la produccion de nuevos derivados de la piperazina. |
| ES359161A Expired ES359161A1 (es) | 1966-09-03 | 1968-10-15 | Procedimiento para la produccion de nuevos derivados de la piperazina. |
| ES359158A Expired ES359158A1 (es) | 1966-09-03 | 1968-10-15 | Procedimiento para la produccion de nuevos derivados de la piperazina. |
| ES359160A Expired ES359160A1 (es) | 1966-09-03 | 1968-10-15 | Procedimiento para la produccion de nuevos derivados de la piperazina. |
| ES359157A Expired ES359157A1 (es) | 1966-09-03 | 1968-10-15 | Procedimiento para la produccion de nuevos derivados de la piperazina. |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES359156A Expired ES359156A1 (es) | 1966-09-03 | 1968-10-15 | Procedimiento para la produccion de nuevos derivados de la piperazina. |
| ES359162A Expired ES359162A1 (es) | 1966-09-03 | 1968-10-15 | Procedimiento para la produccion de nuevos derivados de la piperazina. |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US3729474A (es) |
| AT (7) | AT280289B (es) |
| BE (1) | BE703407A (es) |
| CH (8) | CH505841A (es) |
| DE (1) | DE1670254A1 (es) |
| DK (1) | DK124081B (es) |
| ES (8) | ES344693A1 (es) |
| FI (1) | FI49969C (es) |
| FR (2) | FR1550188A (es) |
| GB (1) | GB1176672A (es) |
| IL (1) | IL28589A (es) |
| NL (2) | NL6712054A (es) |
| SE (1) | SE350260B (es) |
| YU (9) | YU33749B (es) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2037852C3 (de) * | 1970-07-30 | 1980-06-26 | Boehringer Sohn Ingelheim | Neue Piperazinderivate und Verfahren zu ihrer Herstellung |
| US3859438A (en) * | 1971-07-08 | 1975-01-07 | Boehringer Sohn Ingelheim | Pharmaceutical compositions containing an n-(1-bicyclic aryl-propyl-2)-n-bicyclic aryl-piperazine and method of use |
| DE2325633A1 (de) * | 1973-05-21 | 1974-12-12 | Boehringer Sohn Ingelheim | Piperazinderivate |
| US4094980A (en) * | 1974-09-03 | 1978-06-13 | Boehringer Ingelheim Gmbh | N-[1-(3',4'-methylenedioxy-phenyl)-propyl-(2)]-N'-phenyl-piperazines and salts thereof |
| FR2285883A1 (fr) * | 1974-09-30 | 1976-04-23 | Cerm Cent Europ Rech Mauvernay | Nouveaux composes chimiques a activite bronchospasmolytique et antitussive, et procede pour leur obtention |
| US4130646A (en) * | 1975-07-25 | 1978-12-19 | E. R. Squibb & Sons, Inc. | 1,2,3,4-Tetrahydro-2-((4-(phenyl)-1-piperazinyl)methyl)-1-naphthalenols and derivatives and analogs thereof |
| FI60479C (fi) * | 1977-12-22 | 1982-02-10 | Serlachius Oy | Planteringsanordning |
| US4684651A (en) * | 1981-03-17 | 1987-08-04 | Mitsubishi Chemical Industries Limited | Alkylenedioxybenzene and acid addition salts thereof useful as hypotensives |
| US4891375A (en) * | 1988-01-13 | 1990-01-02 | Pfizer Inc. | Arylpiperazinyl-alkylene-phenyl-heterocyclic compounds |
| US6114334A (en) * | 1995-07-13 | 2000-09-05 | Knoll Aktiengesellschaft | Piperazine derivatives as therapeutic agents |
| FR2737724B1 (fr) * | 1995-08-09 | 1997-09-05 | Synthelabo | Derives de 1-[2-(2,3-dihydro-1h-inden-1-yl)ethyl]-4- (naphtalen-1-yl) piperazine, leur preparation et leur application en therapeutique |
| US20070219213A1 (en) * | 2004-05-20 | 2007-09-20 | Soares Romeiro Luiz A | Use of Adrenergic N-Phenylpiperazine Antagonists, Pahrmaceutical Compositions Containning Them, and Methods of Preparing Them |
-
0
- NL NL132357D patent/NL132357C/xx active
-
1967
- 1967-08-01 DE DE19671670254 patent/DE1670254A1/de active Pending
- 1967-08-10 CH CH292670A patent/CH505841A/de not_active IP Right Cessation
- 1967-08-10 CH CH292570A patent/CH517751A/de not_active IP Right Cessation
- 1967-08-10 CH CH292270A patent/CH505838A/de not_active IP Right Cessation
- 1967-08-10 CH CH292170A patent/CH505837A/de not_active IP Right Cessation
- 1967-08-10 CH CH292470A patent/CH505840A/de not_active IP Right Cessation
- 1967-08-10 CH CH1127167A patent/CH506532A/de not_active IP Right Cessation
- 1967-08-10 CH CH292070A patent/CH507964A/de not_active IP Right Cessation
- 1967-08-10 CH CH292370A patent/CH505839A/de not_active IP Right Cessation
- 1967-08-31 AT AT801367A patent/AT280289B/de active
- 1967-08-31 AT AT477669A patent/AT280302B/de not_active IP Right Cessation
- 1967-08-31 AT AT477869A patent/AT280304B/de not_active IP Right Cessation
- 1967-08-31 AT AT477769A patent/AT280303B/de not_active IP Right Cessation
- 1967-08-31 AT AT477569A patent/AT280301B/de not_active IP Right Cessation
- 1967-08-31 AT AT478169A patent/AT280307B/de not_active IP Right Cessation
- 1967-08-31 AT AT478069A patent/AT280306B/de not_active IP Right Cessation
- 1967-09-01 DK DK441867AA patent/DK124081B/da unknown
- 1967-09-01 YU YU1724/67A patent/YU33749B/xx unknown
- 1967-09-01 SE SE12167/67A patent/SE350260B/xx unknown
- 1967-09-01 BE BE703407D patent/BE703407A/xx not_active IP Right Cessation
- 1967-09-01 ES ES344693A patent/ES344693A1/es not_active Expired
- 1967-09-01 NL NL6712054A patent/NL6712054A/xx unknown
- 1967-09-01 FR FR1550188D patent/FR1550188A/fr not_active Expired
- 1967-09-01 FI FI672361A patent/FI49969C/fi active
- 1967-09-01 IL IL28589A patent/IL28589A/en unknown
- 1967-09-04 GB GB40403/67A patent/GB1176672A/en not_active Expired
- 1967-12-01 FR FR130682A patent/FR7515M/fr not_active Expired
-
1968
- 1968-10-15 ES ES359161A patent/ES359161A1/es not_active Expired
- 1968-10-15 ES ES359158A patent/ES359158A1/es not_active Expired
- 1968-10-15 ES ES359160A patent/ES359160A1/es not_active Expired
- 1968-10-15 ES ES359157A patent/ES359157A1/es not_active Expired
- 1968-10-15 ES ES359159A patent/ES359159A1/es not_active Expired
- 1968-10-15 ES ES359156A patent/ES359156A1/es not_active Expired
- 1968-10-15 ES ES359162A patent/ES359162A1/es not_active Expired
-
1971
- 1971-01-28 US US00110766A patent/US3729474A/en not_active Expired - Lifetime
-
1975
- 1975-05-14 YU YU1238/75A patent/YU37326B/xx unknown
- 1975-05-14 YU YU1235/75A patent/YU37323B/xx unknown
- 1975-05-14 YU YU1236/75A patent/YU37324B/xx unknown
- 1975-05-14 YU YU1232/75A patent/YU37320B/xx unknown
- 1975-05-14 YU YU1237/75A patent/YU37325B/xx unknown
- 1975-05-14 YU YU1233/75A patent/YU37321B/xx unknown
- 1975-05-14 YU YU1239/75A patent/YU37327B/xx unknown
- 1975-05-14 YU YU1234/75A patent/YU37322B/xx unknown
Also Published As
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