CH505839A - Verfahren zur Herstellung von neuen racemischen oder optisch aktiven Piperazinderivaten - Google Patents
Verfahren zur Herstellung von neuen racemischen oder optisch aktiven PiperazinderivatenInfo
- Publication number
- CH505839A CH505839A CH292370A CH292370A CH505839A CH 505839 A CH505839 A CH 505839A CH 292370 A CH292370 A CH 292370A CH 292370 A CH292370 A CH 292370A CH 505839 A CH505839 A CH 505839A
- Authority
- CH
- Switzerland
- Prior art keywords
- preparation
- optically active
- piperazine derivatives
- active piperazine
- new racemic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
- C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
- C07D295/03—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
- C07D295/067—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents attached to the same carbon chain, which is not interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/092—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings with aromatic radicals attached to the chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
- C07D295/104—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/108—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE1966B0088772 DE1670144B2 (de) | 1966-09-03 | 1966-09-03 | Substituierte n- eckige klammer auf l-arylpropyl-(2) eckige klammer zu -n'- phenyl-piperazine, verfahren zu deren herstellung und daraus hergestellte zentraldepressiv wirkende pharmazeutische praeparate |
| DEB0093758 | 1967-08-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CH505839A true CH505839A (de) | 1971-04-15 |
Family
ID=25968081
Family Applications (8)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH292270A CH505838A (de) | 1966-09-03 | 1967-08-10 | Verfahren zur Herstellung von neuen racemischen oder optisch aktiven Piperazinderivaten |
| CH1127167A CH506532A (de) | 1966-09-03 | 1967-08-10 | Verfahren zur Herstellung von neuen racemischen oder optisch aktiven Piperazinderivaten |
| CH292570A CH517751A (de) | 1966-09-03 | 1967-08-10 | Verfahren zur Herstellung von neuen racemischen oder optisch aktiven Piperazinderivaten |
| CH292170A CH505837A (de) | 1966-09-03 | 1967-08-10 | Verfahren zur Herstellung von neuen racemischen oder optisch aktiven Piperazinderivaten |
| CH292670A CH505841A (de) | 1966-09-03 | 1967-08-10 | Verfahren zur Herstellung von neuen racemischen oder optisch aktiven Piperazinderivaten |
| CH292470A CH505840A (de) | 1966-09-03 | 1967-08-10 | Verfahren zur Herstellung von neuen racemischen oder optisch aktiven Piperazinderivaten |
| CH292070A CH507964A (de) | 1966-09-03 | 1967-08-10 | Verfahren zur Herstellung von neuen racemischen oder optisch aktiven Piperazinderivaten |
| CH292370A CH505839A (de) | 1966-09-03 | 1967-08-10 | Verfahren zur Herstellung von neuen racemischen oder optisch aktiven Piperazinderivaten |
Family Applications Before (7)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CH292270A CH505838A (de) | 1966-09-03 | 1967-08-10 | Verfahren zur Herstellung von neuen racemischen oder optisch aktiven Piperazinderivaten |
| CH1127167A CH506532A (de) | 1966-09-03 | 1967-08-10 | Verfahren zur Herstellung von neuen racemischen oder optisch aktiven Piperazinderivaten |
| CH292570A CH517751A (de) | 1966-09-03 | 1967-08-10 | Verfahren zur Herstellung von neuen racemischen oder optisch aktiven Piperazinderivaten |
| CH292170A CH505837A (de) | 1966-09-03 | 1967-08-10 | Verfahren zur Herstellung von neuen racemischen oder optisch aktiven Piperazinderivaten |
| CH292670A CH505841A (de) | 1966-09-03 | 1967-08-10 | Verfahren zur Herstellung von neuen racemischen oder optisch aktiven Piperazinderivaten |
| CH292470A CH505840A (de) | 1966-09-03 | 1967-08-10 | Verfahren zur Herstellung von neuen racemischen oder optisch aktiven Piperazinderivaten |
| CH292070A CH507964A (de) | 1966-09-03 | 1967-08-10 | Verfahren zur Herstellung von neuen racemischen oder optisch aktiven Piperazinderivaten |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US3729474A (de) |
| AT (7) | AT280303B (de) |
| BE (1) | BE703407A (de) |
| CH (8) | CH505838A (de) |
| DE (1) | DE1670254A1 (de) |
| DK (1) | DK124081B (de) |
| ES (8) | ES344693A1 (de) |
| FI (1) | FI49969C (de) |
| FR (2) | FR1550188A (de) |
| GB (1) | GB1176672A (de) |
| IL (1) | IL28589A (de) |
| NL (2) | NL6712054A (de) |
| SE (1) | SE350260B (de) |
| YU (9) | YU33749B (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2037852C3 (de) * | 1970-07-30 | 1980-06-26 | Boehringer Sohn Ingelheim | Neue Piperazinderivate und Verfahren zu ihrer Herstellung |
| US3859438A (en) * | 1971-07-08 | 1975-01-07 | Boehringer Sohn Ingelheim | Pharmaceutical compositions containing an n-(1-bicyclic aryl-propyl-2)-n-bicyclic aryl-piperazine and method of use |
| DE2325633A1 (de) * | 1973-05-21 | 1974-12-12 | Boehringer Sohn Ingelheim | Piperazinderivate |
| US4094980A (en) * | 1974-09-03 | 1978-06-13 | Boehringer Ingelheim Gmbh | N-[1-(3',4'-methylenedioxy-phenyl)-propyl-(2)]-N'-phenyl-piperazines and salts thereof |
| FR2285883A1 (fr) * | 1974-09-30 | 1976-04-23 | Cerm Cent Europ Rech Mauvernay | Nouveaux composes chimiques a activite bronchospasmolytique et antitussive, et procede pour leur obtention |
| US4130646A (en) * | 1975-07-25 | 1978-12-19 | E. R. Squibb & Sons, Inc. | 1,2,3,4-Tetrahydro-2-((4-(phenyl)-1-piperazinyl)methyl)-1-naphthalenols and derivatives and analogs thereof |
| FI60479C (fi) * | 1977-12-22 | 1982-02-10 | Serlachius Oy | Planteringsanordning |
| US4684651A (en) * | 1981-03-17 | 1987-08-04 | Mitsubishi Chemical Industries Limited | Alkylenedioxybenzene and acid addition salts thereof useful as hypotensives |
| US4891375A (en) * | 1988-01-13 | 1990-01-02 | Pfizer Inc. | Arylpiperazinyl-alkylene-phenyl-heterocyclic compounds |
| JP4108747B2 (ja) * | 1995-07-13 | 2008-06-25 | アボット ゲゼルシャフト ミット ベシュレンクテル ハフツング ウント コンパニー コマンディトゲゼルシャフト | 治療薬としてのピペラジン誘導体 |
| FR2737724B1 (fr) * | 1995-08-09 | 1997-09-05 | Synthelabo | Derives de 1-[2-(2,3-dihydro-1h-inden-1-yl)ethyl]-4- (naphtalen-1-yl) piperazine, leur preparation et leur application en therapeutique |
| US20070219213A1 (en) * | 2004-05-20 | 2007-09-20 | Soares Romeiro Luiz A | Use of Adrenergic N-Phenylpiperazine Antagonists, Pahrmaceutical Compositions Containning Them, and Methods of Preparing Them |
-
0
- NL NL132357D patent/NL132357C/xx active
-
1967
- 1967-08-01 DE DE19671670254 patent/DE1670254A1/de active Pending
- 1967-08-10 CH CH292270A patent/CH505838A/de not_active IP Right Cessation
- 1967-08-10 CH CH1127167A patent/CH506532A/de not_active IP Right Cessation
- 1967-08-10 CH CH292570A patent/CH517751A/de not_active IP Right Cessation
- 1967-08-10 CH CH292170A patent/CH505837A/de not_active IP Right Cessation
- 1967-08-10 CH CH292670A patent/CH505841A/de not_active IP Right Cessation
- 1967-08-10 CH CH292470A patent/CH505840A/de not_active IP Right Cessation
- 1967-08-10 CH CH292070A patent/CH507964A/de not_active IP Right Cessation
- 1967-08-10 CH CH292370A patent/CH505839A/de not_active IP Right Cessation
- 1967-08-31 AT AT477769A patent/AT280303B/de not_active IP Right Cessation
- 1967-08-31 AT AT477869A patent/AT280304B/de not_active IP Right Cessation
- 1967-08-31 AT AT478069A patent/AT280306B/de not_active IP Right Cessation
- 1967-08-31 AT AT477669A patent/AT280302B/de not_active IP Right Cessation
- 1967-08-31 AT AT478169A patent/AT280307B/de not_active IP Right Cessation
- 1967-08-31 AT AT477569A patent/AT280301B/de not_active IP Right Cessation
- 1967-08-31 AT AT801367A patent/AT280289B/de active
- 1967-09-01 SE SE12167/67A patent/SE350260B/xx unknown
- 1967-09-01 DK DK441867AA patent/DK124081B/da unknown
- 1967-09-01 FI FI672361A patent/FI49969C/fi active
- 1967-09-01 BE BE703407D patent/BE703407A/xx not_active IP Right Cessation
- 1967-09-01 IL IL28589A patent/IL28589A/en unknown
- 1967-09-01 NL NL6712054A patent/NL6712054A/xx unknown
- 1967-09-01 FR FR1550188D patent/FR1550188A/fr not_active Expired
- 1967-09-01 YU YU1724/67A patent/YU33749B/xx unknown
- 1967-09-01 ES ES344693A patent/ES344693A1/es not_active Expired
- 1967-09-04 GB GB40403/67A patent/GB1176672A/en not_active Expired
- 1967-12-01 FR FR130682A patent/FR7515M/fr not_active Expired
-
1968
- 1968-10-15 ES ES359161A patent/ES359161A1/es not_active Expired
- 1968-10-15 ES ES359159A patent/ES359159A1/es not_active Expired
- 1968-10-15 ES ES359158A patent/ES359158A1/es not_active Expired
- 1968-10-15 ES ES359157A patent/ES359157A1/es not_active Expired
- 1968-10-15 ES ES359160A patent/ES359160A1/es not_active Expired
- 1968-10-15 ES ES359162A patent/ES359162A1/es not_active Expired
- 1968-10-15 ES ES359156A patent/ES359156A1/es not_active Expired
-
1971
- 1971-01-28 US US00110766A patent/US3729474A/en not_active Expired - Lifetime
-
1975
- 1975-05-14 YU YU1239/75A patent/YU37327B/xx unknown
- 1975-05-14 YU YU1238/75A patent/YU37326B/xx unknown
- 1975-05-14 YU YU1232/75A patent/YU37320B/xx unknown
- 1975-05-14 YU YU1236/75A patent/YU37324B/xx unknown
- 1975-05-14 YU YU1237/75A patent/YU37325B/xx unknown
- 1975-05-14 YU YU1233/75A patent/YU37321B/xx unknown
- 1975-05-14 YU YU1235/75A patent/YU37323B/xx unknown
- 1975-05-14 YU YU1234/75A patent/YU37322B/xx unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PL | Patent ceased |