ES340412A1 - Procedimiento para la preparacion de derivados de piroin- dol. - Google Patents
Procedimiento para la preparacion de derivados de piroin- dol.Info
- Publication number
- ES340412A1 ES340412A1 ES340412A ES340412A ES340412A1 ES 340412 A1 ES340412 A1 ES 340412A1 ES 340412 A ES340412 A ES 340412A ES 340412 A ES340412 A ES 340412A ES 340412 A1 ES340412 A1 ES 340412A1
- Authority
- ES
- Spain
- Prior art keywords
- alkyl
- formula
- derivatives
- pyroindol
- procedure
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 125000000217 alkyl group Chemical group 0.000 abstract 5
- 150000001875 compounds Chemical class 0.000 abstract 3
- 239000002253 acid Substances 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- RPROHCOBMVQVIV-UHFFFAOYSA-N 2,3,4,5-tetrahydro-1h-pyrido[4,3-b]indole Chemical class N1C2=CC=CC=C2C2=C1CCNC2 RPROHCOBMVQVIV-UHFFFAOYSA-N 0.000 abstract 1
- 230000003266 anti-allergic effect Effects 0.000 abstract 1
- 230000001387 anti-histamine Effects 0.000 abstract 1
- 239000000739 antihistaminic agent Substances 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/42—Radicals substituted by singly-bound nitrogen atoms having hetero atoms attached to the substituent nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US54945566A | 1966-05-12 | 1966-05-12 | |
| US628530A US3409628A (en) | 1966-05-12 | 1967-04-05 | 5-(3-pyridylethyl)pyridoindole derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES340412A1 true ES340412A1 (es) | 1968-06-01 |
Family
ID=27069138
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES340412A Expired ES340412A1 (es) | 1966-05-12 | 1967-05-11 | Procedimiento para la preparacion de derivados de piroin- dol. |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US3409628A (OSRAM) |
| BE (1) | BE698183A (OSRAM) |
| CH (1) | CH494234A (OSRAM) |
| DE (1) | DE1695187A1 (OSRAM) |
| DK (1) | DK123655B (OSRAM) |
| ES (1) | ES340412A1 (OSRAM) |
| FI (1) | FI48093C (OSRAM) |
| FR (2) | FR7024M (OSRAM) |
| GB (3) | GB1173997A (OSRAM) |
| IL (1) | IL27956A (OSRAM) |
| NL (1) | NL6706671A (OSRAM) |
| NO (1) | NO123950B (OSRAM) |
| SE (1) | SE342231B (OSRAM) |
| YU (1) | YU94367A (OSRAM) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4696930A (en) * | 1985-04-12 | 1987-09-29 | Hoffmann-La Roche Inc. | N-(heteroarylalkyl)acylanilide derivatives as antiarrhythmic agents |
| RU2339637C1 (ru) * | 2007-04-05 | 2008-11-27 | Андрей Александрович Иващенко | Блокаторы гистаминного рецептора для фармацевтических композиций, обладающих противоаллергическим и аутоиммунным действием |
| CA2700160A1 (en) * | 2007-09-20 | 2009-03-26 | D2E, Llc | Fluoro-containing derivatives of hydrogenated pyrido[4,3-b]indoles with neuroprotective and cognition enhancing properties, process for preparing, and use |
| RU2007139634A (ru) | 2007-10-25 | 2009-04-27 | Сергей Олегович Бачурин (RU) | Новые тиазол-, триазол- или оксадиазол-содержащие тетрациклические соединения |
| WO2009082268A2 (ru) * | 2007-12-21 | 2009-07-02 | Alla Chem, Llc | ЛИГАНДЫ α-АДРЕНОЦЕПТОРОВ, ДОПАМИНОВЫХ, ГИСТАМИНОВЫХ, ИМИДАЗОЛИНОВЫХ И СЕРОТОНИНОВЫХ РЕЦЕПТОРОВ И ИХ ПРИМЕНЕНИЕ |
| US9063126B2 (en) * | 2008-09-29 | 2015-06-23 | Abbvie Inc. | Indole and indoline derivatives and methods of use thereof |
| US9625475B2 (en) * | 2008-09-29 | 2017-04-18 | Abbvie Inc. | Indole and indoline derivatives and methods of use thereof |
| WO2010067085A2 (en) | 2008-12-12 | 2010-06-17 | Wista Laboratories Ltd. | Synthesis of 9-(arylalkyl)-1,2,3,4-tetrahydro-υ-carboline and analogues and intermediates |
| US9162980B2 (en) | 2009-01-09 | 2015-10-20 | Board Of Regents Of The University Of Texas System | Anti-depression compounds |
| US8362277B2 (en) | 2009-01-09 | 2013-01-29 | Board Of Regents Of The University Of Texas System | Pro-neurogenic compounds |
| US9962368B2 (en) | 2009-01-09 | 2018-05-08 | Board Of Regents Of The University Of Texas System | Pro-neurogenic compounds |
| CN107595841A (zh) * | 2009-01-09 | 2018-01-19 | 得克萨斯州大学系统董事会 | 前神经原性化合物 |
| BRPI1006602A2 (pt) | 2009-04-29 | 2019-01-15 | Medivation Technologies Inc | composto, método para modular um receptor de histamina em um indivíduo, composição farmacêutica, kit e método para tratar um distúrbio cognitivo ou um distúrbio induzido por pelo menos um sintoma associado com a alteração da cognição |
| AU2010282990B2 (en) | 2009-04-29 | 2015-11-05 | Medivation Technologies, Inc. | Pyrido [4, 3-b] indoles and methods of use |
| WO2011008312A2 (en) | 2009-07-14 | 2011-01-20 | Abbott Laboratories | Indole and indoline derivatives and methods of use thereof |
| EP2590647B1 (en) | 2010-07-07 | 2017-11-08 | Board of Regents of the University of Texas System | Pro-neurogenic compounds |
| US8791132B2 (en) | 2011-02-18 | 2014-07-29 | Medivation Technologies, Inc. | Compounds and methods for treatment of hypertension |
| CA2882826A1 (en) | 2012-08-24 | 2014-02-27 | Board Of Regents Of The University Of Texas System | Pro-neurogenic compounds |
| WO2015070237A1 (en) | 2013-11-11 | 2015-05-14 | Board Of Regents Of The University Of Texas System | Neuroprotective chemicals and methods for identifying and using same |
| WO2015070234A2 (en) | 2013-11-11 | 2015-05-14 | Board Of Regents Of The University Of Texas System | Neuroprotective compounds and use thereof |
| US12084440B2 (en) * | 2021-02-01 | 2024-09-10 | Bigespas Ltd. | Polymorph of latrepirdine dihydrochloride |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2786059A (en) * | 1951-04-30 | 1957-03-19 | Schenley Ind Inc | Derivatives of 2-nu-methyl-1, 2, 3, 4-tetrahydro-gamma-carbolines |
-
1967
- 1967-04-05 US US628530A patent/US3409628A/en not_active Expired - Lifetime
- 1967-05-02 CH CH632467A patent/CH494234A/de not_active IP Right Cessation
- 1967-05-05 DE DE19671695187 patent/DE1695187A1/de active Pending
- 1967-05-09 FR FR105641A patent/FR7024M/fr not_active Expired
- 1967-05-09 BE BE698183D patent/BE698183A/xx unknown
- 1967-05-09 FR FR105640A patent/FR1522686A/fr not_active Expired
- 1967-05-10 IL IL27956A patent/IL27956A/en unknown
- 1967-05-11 NO NO168102A patent/NO123950B/no unknown
- 1967-05-11 ES ES340412A patent/ES340412A1/es not_active Expired
- 1967-05-11 GB GB21874/67A patent/GB1173997A/en not_active Expired
- 1967-05-11 GB GB29346/69A patent/GB1173999A/en not_active Expired
- 1967-05-11 YU YU00943/67A patent/YU94367A/xx unknown
- 1967-05-11 GB GB29345/69A patent/GB1173998A/en not_active Expired
- 1967-05-11 DK DK249367AA patent/DK123655B/da unknown
- 1967-05-12 SE SE6699/67A patent/SE342231B/xx unknown
- 1967-05-12 NL NL6706671A patent/NL6706671A/xx unknown
- 1967-05-12 FI FI671366A patent/FI48093C/fi active
Also Published As
| Publication number | Publication date |
|---|---|
| YU94367A (en) | 1974-08-31 |
| GB1173997A (en) | 1969-12-10 |
| SE342231B (OSRAM) | 1972-01-31 |
| BE698183A (OSRAM) | 1967-11-09 |
| FR1522686A (fr) | 1968-04-26 |
| CH494234A (de) | 1970-07-31 |
| FR7024M (OSRAM) | 1969-06-09 |
| FI48093B (OSRAM) | 1974-02-28 |
| NO123950B (OSRAM) | 1972-02-07 |
| GB1173999A (en) | 1969-12-10 |
| FI48093C (fi) | 1974-06-10 |
| GB1173998A (en) | 1969-12-10 |
| NL6706671A (OSRAM) | 1967-11-13 |
| DK123655B (da) | 1972-07-17 |
| US3409628A (en) | 1968-11-05 |
| IL27956A (en) | 1972-06-28 |
| DE1695187A1 (de) | 1971-04-08 |
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