ES336256A1 - Procedimiento para preparar un compuesto de azaspiroalcano-diona. - Google Patents

Procedimiento para preparar un compuesto de azaspiroalcano-diona.

Info

Publication number
ES336256A1
ES336256A1 ES336256A ES336256A ES336256A1 ES 336256 A1 ES336256 A1 ES 336256A1 ES 336256 A ES336256 A ES 336256A ES 336256 A ES336256 A ES 336256A ES 336256 A1 ES336256 A1 ES 336256A1
Authority
ES
Spain
Prior art keywords
formula
prepared
reaction
reduction
piperazine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES336256A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mead Johnson and Co LLC
Original Assignee
Mead Johnson and Co LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mead Johnson and Co LLC filed Critical Mead Johnson and Co LLC
Publication of ES336256A1 publication Critical patent/ES336256A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/20—Spiro-condensed ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Emergency Lowering Means (AREA)
ES336256A 1966-02-01 1967-01-21 Procedimiento para preparar un compuesto de azaspiroalcano-diona. Expired ES336256A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US52394566A 1966-02-01 1966-02-01
US607908A US3398151A (en) 1966-02-01 1967-01-09 Azaspirodecanediones and azaspiroundecanediones

Publications (1)

Publication Number Publication Date
ES336256A1 true ES336256A1 (es) 1968-06-01

Family

ID=27061323

Family Applications (1)

Application Number Title Priority Date Filing Date
ES336256A Expired ES336256A1 (es) 1966-02-01 1967-01-21 Procedimiento para preparar un compuesto de azaspiroalcano-diona.

Country Status (14)

Country Link
US (1) US3398151A (es)
AT (1) AT278806B (es)
BE (1) BE693497A (es)
CH (1) CH494766A (es)
DE (1) DE1695390B2 (es)
DK (1) DK120750B (es)
ES (1) ES336256A1 (es)
FI (1) FI48590C (es)
FR (1) FR6687M (es)
GB (1) GB1164503A (es)
IL (1) IL27284A (es)
NL (1) NL6701538A (es)
NO (1) NO121156B (es)
SE (1) SE332177B (es)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE759371A (fr) * 1969-11-24 1971-05-24 Bristol Myers Co Azaspirodecanediones heterocycliques et procedes pour leur preparation
US3976776A (en) * 1972-12-06 1976-08-24 Mead Johnson & Company Tranquilizer process employing N-(heteroarcyclic)piperazinylalkylazaspiroalkanediones
US4123538A (en) * 1977-08-30 1978-10-31 Mcneil Laboratories, Incorporated (2-Amino-2-oxoethoxy)acetic acid compounds, compositions and methods
US4309541A (en) * 1978-09-20 1982-01-05 Ciba-Geigy Corporation Piperidinyl-lactams
US4305944A (en) * 1980-09-08 1981-12-15 Mead Johnson & Company N-[(4-[3-cyano substituted pyridyl]piperazino)alkyl]-azaspirodecanediones
US4320131A (en) * 1981-03-16 1982-03-16 Mead Johnson & Company N-[(4-Phenyl-1,2,3,6-tetrahydropyridin-1-yl)alkylene]azaspiroalkanediones and N-[(4-hydroxy-4-phenylpiperidin-1-yl)alkylene]azaspiroalkanediones
US4456756A (en) * 1981-08-03 1984-06-26 Mead Johnson & Company Spirothiazolidinyl piperazine derivatives
US4367335A (en) * 1981-08-03 1983-01-04 Mead Johnson & Company Thiazolidinylalkylene piperazine derivatives
US4411901A (en) * 1981-12-23 1983-10-25 Mead Johnson & Company Benzisothiazole and benzisoxazole piperazine derivatives
US4507303A (en) * 1981-12-22 1985-03-26 Sumitomo Chemical Company, Limited Succinimide derivatives, compositions and method of use
US4452799A (en) * 1981-12-23 1984-06-05 Mead Johnson & Company Benzisothiazole and benzisoxazole piperazine derivatives
US4423049A (en) * 1981-12-28 1983-12-27 Mead Johnson & Company 2-[4-[(4,4-Dialkyl-2,6-piperidinedion-1-yl)butyl]-1-piperazinyl]pyrimidines
US4361565A (en) * 1981-12-28 1982-11-30 Mead Johnson & Company 2-[4-[(4,4-Dialkyl-2,6-piperidinedion-1-yl)butyl]-1-piperazinyl]pyridines
US4515947A (en) * 1982-08-11 1985-05-07 Eastman Kodak Company Cyanoalkylpiperazines and methods for their preparation and use
US4620006A (en) * 1982-08-11 1986-10-28 Eastman Kodak Company Acid salts of 1-(cyanoalkyl)-4-guanylpiperazines
US4620002A (en) * 1982-08-11 1986-10-28 Eastman Kodak Company 2-pyrimidyl alkanesulfonates
JPS5976059A (ja) * 1982-10-21 1984-04-28 Sumitomo Chem Co Ltd 環状イミド誘導体及びその酸付加塩
GB2139217B (en) * 1983-02-07 1986-07-09 Bristol Myers Co Antipsychotic 5-fluoro-pyrimidin-2-yl piperazine compound
US4581357A (en) * 1983-02-07 1986-04-08 Mead Johnson & Company Antipsychotic 5-fluoro-pyrimidin-2-yl piperazine compound
US4524206A (en) * 1983-09-12 1985-06-18 Mead Johnson & Company 1-Heteroaryl-4-(2,5-pyrrolidinedion-1-yl)alkyl)piperazine derivatives
JPH0625181B2 (ja) * 1985-03-27 1994-04-06 住友製薬株式会社 新規なイミド誘導体
AR242678A1 (es) * 1986-03-05 1993-04-30 Gonzalez Jorge Alberto Mejoras en instrumentos musicales de cuerda de arco.
PH25227A (en) * 1986-03-05 1991-03-27 Merrell Dow France Et Co Aromatic w-alkylamino-tetrahydro-6h-1,3-thiazin-6-one derivatives, pharmaceutical composition containing same and method of use thereof
AU593194B2 (en) * 1986-09-26 1990-02-01 Sumitomo Pharmaceuticals Company, Limited Imide derivatives ,and their production and use
FR2608157B1 (fr) * 1986-12-11 1989-09-08 Roussel Uclaf Nouveaux derives de l'azaspirodecane, leurs sels, procede de preparation, application a titre de medicaments et compositions les renfermant et intermediaires
FR2621586B1 (fr) * 1987-10-08 1990-02-02 Roussel Uclaf Nouveaux derives de l'azapirodecane, leur procede de preparation et leur application comme medicaments
IE62890B1 (en) * 1988-12-06 1995-03-08 Hafslund Nycomed Pharma New piperazinylalkyl-3(2h)-pyridazinones process for the preparation thereof and the use thereof as agents lowering blood pressure
US5162321A (en) * 1989-12-20 1992-11-10 Adir Et Compagnie 1-naphthyl piperazines useful as 5-HT1A receptor ligands
ES2019228A6 (es) * 1990-02-13 1991-06-01 Espanola Prod Quimicos Procedimiento de obtencion de nuevos derivados de azaspiro (4.5) decano-7, 9-diona.
US5098904A (en) * 1990-06-27 1992-03-24 Bristol-Myers Squibb Company Cerebral function enhancing pyrimidinyl derivatives
US5130315A (en) * 1991-01-10 1992-07-14 Raymond R. Wittekind 1-piperazinyl-2-butenes and -2-butynes
US5137894A (en) * 1991-12-05 1992-08-11 New James S 4-(4-Piperidinyl-thieno[3,2-c]pyridine derivatives of n-alkylglutarimides
SE9201138D0 (sv) * 1992-04-09 1992-04-09 Astra Ab Novel phthalimidoalkylpiperazines
CA2338037A1 (en) 1998-07-17 2000-01-27 Synaptic Pharmaceutical Corporation Compounds specific for the human .alpha.1d adrenergic receptor and uses thereof
US20040106623A1 (en) * 1999-07-16 2004-06-03 Synaptic Pharmaceutical Corporation Compounds specific for the human alpha1d adrenergic receptor and uses thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3030366A (en) * 1961-01-25 1962-04-17 Lakeside Lab Inc Piperazinoalkyl glycolamides

Also Published As

Publication number Publication date
US3398151A (en) 1968-08-20
NO121156B (es) 1971-01-25
FR6687M (es) 1969-02-10
DE1695390A1 (de) 1972-02-24
GB1164503A (en) 1969-09-17
IL27284A (en) 1971-08-25
DK120750B (da) 1971-07-12
NL6701538A (es) 1967-08-02
FI48590B (es) 1974-07-31
AT278806B (de) 1970-02-10
SE332177B (es) 1971-02-01
FI48590C (fi) 1974-11-11
BE693497A (es) 1967-08-01
CH494766A (de) 1970-08-15
DE1695390B2 (de) 1976-11-11

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