ES323083A1 - Procedure for the manufacture of naftalene derivatives. (Machine-translation by Google Translate, not legally binding) - Google Patents
Procedure for the manufacture of naftalene derivatives. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES323083A1 ES323083A1 ES0323083A ES323083A ES323083A1 ES 323083 A1 ES323083 A1 ES 323083A1 ES 0323083 A ES0323083 A ES 0323083A ES 323083 A ES323083 A ES 323083A ES 323083 A1 ES323083 A1 ES 323083A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- compound
- naphthalene nucleus
- reacted
- radical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/04—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D263/06—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by oxygen atoms, attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
"Procedure for the manufacture of naphthalene derivatives" of the formula **(See formula)** -wherein R1 represents hydrogen or an alkyl, cycloalkyl or aralkyl radical, each of which may optionally be substituted, and in which the naphthalene nucleus carries at least one substituent chosen from the hydroxy, alkoxy and acyloxy radicals and can optionally carrying one or more additional substituents- and the esters thereof and the salts thereof, and the oxazolidines prepared therefrom, characterized in that: (a) a compound of the formula is reacted, **(See formula)** -in which A represents the group (see formula); X represents a halogen atom in which the naphthalene nucleus carries at least one substituent chosen from the alkoxy and acyloxy radicals, and can optionally carry one or more additional substituents - with an amine of the formula R1.NH2, in which R1 has the meaning indicated above; or (b) a compound of the formula is reacted, **(See formula)** -wherein the naphthalene nucleus is replaced as indicated in (a) above, with a compound of the formula, **(See formula)** in which R1 and X have the meanings indicated above; or (c) a compound of the formula is reacted, **(See formula)** -wherein R1 has the meaning indicated above, and wherein the naphthalene nucleus carries at least one alkoxy substituent and can optionally carry one or more additional substituents with a dealkylating agent; or (d) an amino derivative of the formula is reacted, **(See formula)** -wherein the naphthalene nucleus carries at least one substituent selected from hydroxy, alkoxy and acyloxy radicals, and can optionally carry one or more additional substituents, with a carbonyl compound of the formula R3.CO.R4, where R3 represents hydrogen or an alkyl radical, optionally substituted and R4 represents an alkyl, cycloalkyl, aryl or aralkyl radical, optionally substituted, or in which R3 and R4 join together with the adjacent carbon atom to form an optionally substituted cycloalkyl radical, provided that the radical -CHR3R4 has the same meaning defined above for R1, under reduced conditions; or (e) a compound of the formula is reacted, **(See formula)** -where R1 has the above meaning, R5 represents a hydrogenolizable radical, and the naphthalene nucleus is replaced as indicated in (d) above with hydrogen in the presence of a hydrogenation catalyst; or (f) a compound of the formula is acylated, **(See formula)** -in which R1 has the meaning indicated above, and the naphthalene nucleus is replaced as indicated in (d) above- with an acylating agent derived from an acid of the formula, R2COOH, in which R2 represents an alkyl radical, alkenyl or aryl, optionally substituted; or (g) a compound of the formula is reacted, **(See formula)** -in which R1 has the meaning indicated above, and the naphthalene nucleus is replaced as indicated in (d) above- with an aldehyde of the formula R6.CHO, in which R6 represents hydrogen or an alkyl radical, after which, if desired, the product is converted to a salt by reaction with an acid. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9092/65A GB1066613A (en) | 1965-03-03 | 1965-03-03 | Naphthalene derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES323083A1 true ES323083A1 (en) | 1967-01-01 |
Family
ID=9865202
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES0323083A Expired ES323083A1 (en) | 1965-03-03 | 1966-02-15 | Procedure for the manufacture of naftalene derivatives. (Machine-translation by Google Translate, not legally binding) |
Country Status (14)
| Country | Link |
|---|---|
| AT (6) | AT264511B (en) |
| BE (1) | BE676821A (en) |
| BR (1) | BR6677439D0 (en) |
| CH (1) | CH486420A (en) |
| DE (1) | DE1543685A1 (en) |
| DK (1) | DK122274B (en) |
| ES (1) | ES323083A1 (en) |
| FI (1) | FI44622C (en) |
| FR (1) | FR5516M (en) |
| GB (1) | GB1066613A (en) |
| IL (1) | IL25132A (en) |
| NL (1) | NL6601686A (en) |
| NO (1) | NO115028B (en) |
| SE (1) | SE316191B (en) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2644833A1 (en) * | 1976-10-05 | 1978-04-20 | Boehringer Sohn Ingelheim | NEW 1-ARYLOXY-2-HYDROXY-3-ALKYLENE AMINOPROPANES AND METHOD FOR THE PRODUCTION THEREOF |
| US4376125A (en) * | 1980-11-05 | 1983-03-08 | University Of Virginia Alumni Patents Foundation | Aminobenzlpropranolol and pharmaceutical preparation thereof |
| US8542005B2 (en) | 2010-04-28 | 2013-09-24 | Teradyne, Inc. | Connecting digital storage oscilloscopes |
| US8098181B2 (en) | 2010-04-28 | 2012-01-17 | Teradyne, Inc. | Attenuator circuit |
| US8502522B2 (en) | 2010-04-28 | 2013-08-06 | Teradyne, Inc. | Multi-level triggering circuit |
| US8531176B2 (en) | 2010-04-28 | 2013-09-10 | Teradyne, Inc. | Driving an electronic instrument |
| CN114224875B (en) * | 2021-11-04 | 2023-08-11 | 中南大学湘雅医院 | New use of alcohol compound and antitumor drug |
-
1965
- 1965-03-03 GB GB9092/65A patent/GB1066613A/en not_active Expired
-
1966
- 1966-02-02 NO NO161543A patent/NO115028B/no unknown
- 1966-02-04 DE DE19661543685 patent/DE1543685A1/en active Pending
- 1966-02-07 IL IL25132A patent/IL25132A/en unknown
- 1966-02-10 NL NL6601686A patent/NL6601686A/xx unknown
- 1966-02-14 SE SE1873/66A patent/SE316191B/xx unknown
- 1966-02-15 FI FI660373A patent/FI44622C/en active
- 1966-02-15 ES ES0323083A patent/ES323083A1/en not_active Expired
- 1966-02-21 BE BE676821D patent/BE676821A/xx unknown
- 1966-02-22 AT AT438067A patent/AT264511B/en active
- 1966-02-22 AT AT438267A patent/AT264513B/en active
- 1966-02-22 AT AT438367A patent/AT264504B/en active
- 1966-02-22 AT AT437967A patent/AT264510B/en active
- 1966-02-22 AT AT164866A patent/AT264509B/en active
- 1966-02-22 AT AT438167A patent/AT264512B/en active
- 1966-02-25 CH CH276766A patent/CH486420A/en not_active IP Right Cessation
- 1966-03-01 BR BR177439/66A patent/BR6677439D0/en unknown
- 1966-03-03 DK DK111866AA patent/DK122274B/en unknown
- 1966-06-02 FR FR63857A patent/FR5516M/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| BR6677439D0 (en) | 1973-09-18 |
| AT264513B (en) | 1968-09-10 |
| DE1543685A1 (en) | 1969-12-18 |
| NL6601686A (en) | 1966-09-05 |
| BE676821A (en) | 1966-08-22 |
| AT264512B (en) | 1968-09-10 |
| FI44622B (en) | 1971-08-31 |
| AT264509B (en) | 1968-09-10 |
| FR5516M (en) | 1967-11-06 |
| AT264504B (en) | 1968-09-10 |
| FI44622C (en) | 1971-12-10 |
| AT264510B (en) | 1968-09-10 |
| NO115028B (en) | 1968-07-08 |
| DK122274B (en) | 1972-02-14 |
| CH486420A (en) | 1970-02-28 |
| GB1066613A (en) | 1967-04-26 |
| AT264511B (en) | 1968-09-10 |
| SE316191B (en) | 1969-10-20 |
| IL25132A (en) | 1969-11-30 |
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