ES3068290T3 - Compounds and methods for treating lupus - Google Patents
Compounds and methods for treating lupusInfo
- Publication number
- ES3068290T3 ES3068290T3 ES17781337T ES17781337T ES3068290T3 ES 3068290 T3 ES3068290 T3 ES 3068290T3 ES 17781337 T ES17781337 T ES 17781337T ES 17781337 T ES17781337 T ES 17781337T ES 3068290 T3 ES3068290 T3 ES 3068290T3
- Authority
- ES
- Spain
- Prior art keywords
- compound
- groups
- dihydro
- alkyl
- mice
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4245—Oxadiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662401762P | 2016-09-29 | 2016-09-29 | |
| PCT/US2017/054053 WO2018064356A1 (en) | 2016-09-29 | 2017-09-28 | Compounds and methods for treating lupus |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES3068290T3 true ES3068290T3 (en) | 2026-05-28 |
Family
ID=60043386
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES17781337T Active ES3068290T3 (en) | 2016-09-29 | 2017-09-28 | Compounds and methods for treating lupus |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US11278526B2 (enExample) |
| EP (1) | EP3518922B1 (enExample) |
| JP (1) | JP7086945B2 (enExample) |
| KR (1) | KR102408814B1 (enExample) |
| CA (1) | CA3038106A1 (enExample) |
| ES (1) | ES3068290T3 (enExample) |
| WO (1) | WO2018064356A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT3630738T (pt) * | 2017-05-22 | 2023-10-24 | Egyt Gyogyszervegyeszeti Gyar | Processo para a produção de ozanimod |
| AR116479A1 (es) | 2018-09-25 | 2021-05-12 | Quim Sintetica S A | Intermediarios para la síntesis de ozanimod y procedimiento para la preparación del mencionado agonista del receptor de esfingosina-1-fosfato y de dichos intermediarios |
| CN113891883A (zh) * | 2019-03-29 | 2022-01-04 | 瑞塞普托斯公司 | 1-磷酸鞘氨醇受体调节剂 |
| CN116332794B (zh) * | 2021-12-24 | 2024-10-15 | 上海合全药物研发有限公司 | 一种芳基腈类化合物的制备方法 |
| IL319505A (en) * | 2022-09-14 | 2025-05-01 | Viatris Asia Pacific Pte Ltd | S1P 1 receptor modulators for use in the treatment of diseases mediated by type 1 interferon |
| WO2026035999A1 (en) | 2024-08-09 | 2026-02-12 | Triana Biomedicines, Inc. | Anaplastic lymphoma kinase (alk) degraders and uses thereof |
| CN122301787A (zh) * | 2024-12-31 | 2026-06-30 | 南京易腾药物研究院有限公司 | 一种季铵盐类局部作用的1-磷酸鞘氨醇受体亚型1激动剂 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20080306124A1 (en) | 2005-06-08 | 2008-12-11 | Rainer Albert | Polycyclic Oxadiazoles or I Soxazoles and Their Use as Sip Receptor Ligands |
| CN101522646A (zh) | 2006-09-29 | 2009-09-02 | 诺瓦提斯公司 | 具有抗炎和免疫抑制特性的二唑衍生物 |
| JO2701B1 (en) | 2006-12-21 | 2013-03-03 | جلاكسو جروب ليميتد | Vehicles |
| PT2291080E (pt) | 2008-05-14 | 2015-10-30 | Scripps Research Inst | Novos modelamodeladores dos recetores da esfingosina fosfato |
| PL2498610T5 (pl) | 2009-11-13 | 2024-11-04 | Receptos Llc | Selektywne modulatory receptora sfingozyno-1-fosforanu i sposoby syntezy chiralnej |
| WO2015066515A1 (en) * | 2013-11-01 | 2015-05-07 | Receptos, Inc. | Selective sphingosine 1 phosphate receptor modulators and combination therapy therewith |
-
2017
- 2017-09-28 CA CA3038106A patent/CA3038106A1/en active Pending
- 2017-09-28 ES ES17781337T patent/ES3068290T3/es active Active
- 2017-09-28 JP JP2019517027A patent/JP7086945B2/ja active Active
- 2017-09-28 EP EP17781337.5A patent/EP3518922B1/en active Active
- 2017-09-28 KR KR1020197011411A patent/KR102408814B1/ko active Active
- 2017-09-28 US US16/337,292 patent/US11278526B2/en active Active
- 2017-09-28 WO PCT/US2017/054053 patent/WO2018064356A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| CA3038106A1 (en) | 2018-04-05 |
| KR20190060791A (ko) | 2019-06-03 |
| EP3518922B1 (en) | 2026-02-11 |
| EP3518922A1 (en) | 2019-08-07 |
| US11278526B2 (en) | 2022-03-22 |
| WO2018064356A1 (en) | 2018-04-05 |
| JP7086945B2 (ja) | 2022-06-20 |
| US20190224172A1 (en) | 2019-07-25 |
| JP2019529487A (ja) | 2019-10-17 |
| KR102408814B1 (ko) | 2022-06-14 |