ES3050631T3 - Method for continuous production of a granulate agent - Google Patents

Method for continuous production of a granulate agent

Info

Publication number
ES3050631T3
ES3050631T3 ES20722226T ES20722226T ES3050631T3 ES 3050631 T3 ES3050631 T3 ES 3050631T3 ES 20722226 T ES20722226 T ES 20722226T ES 20722226 T ES20722226 T ES 20722226T ES 3050631 T3 ES3050631 T3 ES 3050631T3
Authority
ES
Spain
Prior art keywords
active ingredient
particles
solid particles
process space
spray composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES20722226T
Other languages
English (en)
Spanish (es)
Inventor
Reinhard Nowak
Norbert Pöllinger
Annette Grave
Michael Jacob
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ADD Advanced Drug Delivery Technologies AG
Original Assignee
ADD Advanced Drug Delivery Technologies AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ADD Advanced Drug Delivery Technologies AG filed Critical ADD Advanced Drug Delivery Technologies AG
Application granted granted Critical
Publication of ES3050631T3 publication Critical patent/ES3050631T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Glanulating (AREA)
ES20722226T 2019-04-11 2020-04-09 Method for continuous production of a granulate agent Active ES3050631T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP19168673.2A EP3721870A1 (de) 2019-04-11 2019-04-11 Verfahren zur kontinuierlichen herstellung eines wirkstoffgranulats
PCT/EP2020/060277 WO2020208201A1 (de) 2019-04-11 2020-04-09 Verfahren zur kontinuierlichen herstellung eines wirkstoffgranulats

Publications (1)

Publication Number Publication Date
ES3050631T3 true ES3050631T3 (en) 2025-12-22

Family

ID=66105201

Family Applications (1)

Application Number Title Priority Date Filing Date
ES20722226T Active ES3050631T3 (en) 2019-04-11 2020-04-09 Method for continuous production of a granulate agent

Country Status (10)

Country Link
US (1) US20220323361A1 (enExample)
EP (2) EP3721870A1 (enExample)
JP (1) JP7620565B2 (enExample)
CN (1) CN114126591A (enExample)
AU (1) AU2020272151B2 (enExample)
BR (1) BR112021020320A2 (enExample)
CA (1) CA3136529A1 (enExample)
ES (1) ES3050631T3 (enExample)
IL (1) IL287126B1 (enExample)
WO (1) WO2020208201A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3721871A1 (de) * 2019-04-11 2020-10-14 ADD Advanced Drug Delivery Technologies, Ltd. Verfahren zur kontinuierlichen herstellung eines wirkstoffgranulats
EP4251294A1 (en) * 2020-11-24 2023-10-04 Nanoform Finland PLC System, apparatuses, devices, and methods for producing particles
CN116422227B (zh) * 2022-12-09 2024-01-30 山东奥诺能源科技股份有限公司 一种流化床造粒机

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19514187C1 (de) * 1995-04-21 1996-05-15 Degussa Verfahren und Vorrichtung zur Herstellung von Granulaten durch Wirbelschicht-Sprühgranulation
US6117451A (en) 1998-08-25 2000-09-12 Pharmalogix, Inc. Direct compression metformin hydrochloride tablets
DE10004939C1 (de) 2000-02-05 2001-08-23 Lothar Moerl Steuerbare Gasanströmeinrichtung für Strahlschichtapparate
DE60211769T2 (de) * 2001-03-07 2007-05-24 Dainippon Sumitomo Pharma Co., Ltd. Verfahren zur Herstellung von Arzneistoffgranulatkörnern, die Arzneistoffgranulatkörner sowie diese enthaltende pharmazeutische Zubereitungen
US6667054B2 (en) 2001-12-05 2003-12-23 Bernard Charles Sherman Metformin hydrochloride tablets
DE10322062A1 (de) 2003-05-15 2004-12-02 Glatt Ingenieurtechnik Gmbh Verfahren und Vorrichtung zum Aufbringen von Flüssigkeiten in eine Feststoffströmung eines Strahlschichtapparates
CA2528637C (en) 2003-06-11 2012-10-23 Glatt Ingenieurtechnik Gmbh Method for production of enzyme granules and enzyme granules produced thus
BRPI0512829A (pt) * 2004-07-01 2008-04-08 Warner Lambert Co preparação de composições farmacêuticas contendo nanopartìculas
DE102007012105A1 (de) * 2007-03-13 2008-09-18 Add Advanced Drug Delivery Technologies Ltd. Pellets enthaltend pharmazeutische Substanz, Verfahren zu deren Herstellung und deren Verwendung
EP2590631B1 (en) * 2010-07-06 2016-10-26 Janssen Pharmaceutica NV Formulation for co-therapy treatment of diabetes
EP2704696A1 (en) * 2012-03-26 2014-03-12 Glatt AG Taste-masked ibuprofen granules
WO2015012365A1 (ja) * 2013-07-25 2015-01-29 株式会社 三和化学研究所 医薬製剤
KR101642193B1 (ko) * 2014-10-13 2016-07-25 씨제이헬스케어 주식회사 메트포르민 서방성 제제 및 그의 제조방법
WO2018034627A1 (en) * 2016-08-18 2018-02-22 İlko Ilaç Sanayi Ve Ticaret Anonim Şirketi Pharmaceutical composition of antidiabetic tablet

Also Published As

Publication number Publication date
AU2020272151B2 (en) 2025-07-03
EP3952843A1 (de) 2022-02-16
IL287126B1 (en) 2026-01-01
BR112021020320A2 (pt) 2021-12-14
CN114126591A (zh) 2022-03-01
IL287126A (en) 2022-01-01
US20220323361A1 (en) 2022-10-13
JP2022528570A (ja) 2022-06-14
EP3952843B1 (de) 2025-08-06
EP3721870A1 (de) 2020-10-14
JP7620565B2 (ja) 2025-01-23
CA3136529A1 (en) 2020-10-15
AU2020272151A1 (en) 2021-12-09
WO2020208201A1 (de) 2020-10-15

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