ES2981381T3 - Porcinos resistentes al virus del síndrome respiratorio y reproductivo porcino (PRRSV) y células que tienen genes CD163 modificados - Google Patents
Porcinos resistentes al virus del síndrome respiratorio y reproductivo porcino (PRRSV) y células que tienen genes CD163 modificados Download PDFInfo
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| US20200377881A1 (en) * | 2017-03-24 | 2020-12-03 | President And Fellows Of Harvard College | Methods of Genome Engineering by Nuclease-Transposase Fusion Proteins |
| CN107354170A (zh) * | 2017-08-24 | 2017-11-17 | 中国农业科学院北京畜牧兽医研究所 | 一种基因敲除载体以及制备cd163基因敲除猪成纤维细胞的方法 |
| US12060403B2 (en) | 2017-10-16 | 2024-08-13 | Kansas State University Research Foundation | Methods and compositions for treating and protecting against porcine reproductive and respiratory syndrome virus |
| CN107937345B (zh) * | 2017-11-16 | 2019-01-29 | 山东蓝思种业股份有限公司 | 一种制备同时敲除cd163基因和cd13基因的猪成纤维细胞的方法 |
| KR20240108545A (ko) * | 2018-04-17 | 2024-07-09 | 더 큐레이터스 오브 더 유니버시티 오브 미주리 | 바이러스에 의한 감염으로부터 돼지 태아를 보호하는 방법 |
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| CN108753832A (zh) * | 2018-04-20 | 2018-11-06 | 中山大学 | 一种利用CRISPR/Cas9编辑大白猪CD163基因的方法 |
| KR102059503B1 (ko) | 2018-07-31 | 2019-12-26 | 충북대학교 산학협력단 | 돼지생식기호흡기증후군 바이러스 저항성 개체 판별을 위한 단일염기다형성 마커 조성물 |
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| WO2020198541A1 (en) * | 2019-03-27 | 2020-10-01 | Recombinetics, Inc. | Porcine reproductive and respiratory syndrome virus (prrsv) resistant swine |
| CN110438155A (zh) * | 2019-08-15 | 2019-11-12 | 中国农业科学院北京畜牧兽医研究所 | 修饰cd163基因第561位氨基酸的组合物、应用、细胞及基因编辑猪的制备方法 |
| CN110684723B (zh) * | 2019-11-21 | 2021-03-12 | 东北农业大学 | 一种猪卵母细胞体外成熟培养液及其制备方法与应用 |
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| CA3179710A1 (en) * | 2020-05-05 | 2021-11-11 | Andrew Mark CIGAN | Methods for improving the health of porcine species by targeted inactivation of cd163 |
| CN113512534B (zh) * | 2020-09-23 | 2024-04-23 | 杭州启函生物科技有限公司 | 用于遗传修饰和靶向的组合物和方法 |
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| CN112094866B (zh) * | 2020-11-10 | 2021-05-11 | 北京首农未来生物科技有限公司 | 一种利用SpRY-Cas9系统制备CD163基因编辑猪的方法 |
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