ES2970878T3 - Composiciones de vacuna que comprenden una proteína de unión al factor H mutada - Google Patents

Composiciones de vacuna que comprenden una proteína de unión al factor H mutada Download PDF

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Publication number
ES2970878T3
ES2970878T3 ES18209661T ES18209661T ES2970878T3 ES 2970878 T3 ES2970878 T3 ES 2970878T3 ES 18209661 T ES18209661 T ES 18209661T ES 18209661 T ES18209661 T ES 18209661T ES 2970878 T3 ES2970878 T3 ES 2970878T3
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ES
Spain
Prior art keywords
factor
binding protein
binding
composition
meningitidis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES18209661T
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English (en)
Spanish (es)
Inventor
Rachel Exley
Christoph Tang
Susan Lea
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ip2ipo Innovations Ltd
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Ip2ipo Innovations Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Ip2ipo Innovations Ltd filed Critical Ip2ipo Innovations Ltd
Application granted granted Critical
Publication of ES2970878T3 publication Critical patent/ES2970878T3/es
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/095Neisseria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ES18209661T 2008-10-25 2009-10-26 Composiciones de vacuna que comprenden una proteína de unión al factor H mutada Active ES2970878T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0819633.9A GB0819633D0 (en) 2008-10-25 2008-10-25 Composition

Publications (1)

Publication Number Publication Date
ES2970878T3 true ES2970878T3 (es) 2024-05-31

Family

ID=40133849

Family Applications (1)

Application Number Title Priority Date Filing Date
ES18209661T Active ES2970878T3 (es) 2008-10-25 2009-10-26 Composiciones de vacuna que comprenden una proteína de unión al factor H mutada

Country Status (23)

Country Link
US (1) US20120052092A1 (cg-RX-API-DMAC7.html)
EP (2) EP3501534B1 (cg-RX-API-DMAC7.html)
JP (2) JP5676458B2 (cg-RX-API-DMAC7.html)
KR (3) KR20170000390A (cg-RX-API-DMAC7.html)
CN (2) CN105412920A (cg-RX-API-DMAC7.html)
AU (1) AU2009306114B2 (cg-RX-API-DMAC7.html)
BR (1) BRPI0919926A2 (cg-RX-API-DMAC7.html)
CA (1) CA2741619A1 (cg-RX-API-DMAC7.html)
CO (1) CO6382140A2 (cg-RX-API-DMAC7.html)
DK (1) DK3501534T5 (cg-RX-API-DMAC7.html)
ES (1) ES2970878T3 (cg-RX-API-DMAC7.html)
FI (1) FI3501534T3 (cg-RX-API-DMAC7.html)
GB (1) GB0819633D0 (cg-RX-API-DMAC7.html)
HR (1) HRP20240226T1 (cg-RX-API-DMAC7.html)
HU (1) HUE065348T2 (cg-RX-API-DMAC7.html)
LT (1) LT3501534T (cg-RX-API-DMAC7.html)
MX (1) MX2011004322A (cg-RX-API-DMAC7.html)
NZ (2) NZ601538A (cg-RX-API-DMAC7.html)
PL (1) PL3501534T3 (cg-RX-API-DMAC7.html)
PT (1) PT3501534T (cg-RX-API-DMAC7.html)
RU (1) RU2559528C2 (cg-RX-API-DMAC7.html)
SI (1) SI3501534T1 (cg-RX-API-DMAC7.html)
WO (1) WO2010046715A1 (cg-RX-API-DMAC7.html)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX343752B (es) 1998-05-01 2016-11-22 Novartis Vaccines & Diagnostics Inc Antigenos de neisseria meningitidis y composiciones que los contienen.
WO2000071725A2 (en) 1999-05-19 2000-11-30 Chiron S.P.A. Combination neisserial compositions
PT2275551E (pt) 1999-10-29 2015-06-29 Novartis Vaccines & Diagnostic Péptidos antigénicos de neisseria
ATE503837T1 (de) 2000-02-28 2011-04-15 Novartis Vaccines & Diagnostic Hybride expression neisserscher proteine
GB0118249D0 (en) 2001-07-26 2001-09-19 Chiron Spa Histidine vaccines
GB0121591D0 (en) 2001-09-06 2001-10-24 Chiron Spa Hybrid and tandem expression of neisserial proteins
ATE492288T1 (de) 2002-10-11 2011-01-15 Novartis Vaccines & Diagnostic Polypeptidimpstoffe zum breiten schutz gegen hypervirulente meningokokken-linien
GB0227346D0 (en) 2002-11-22 2002-12-31 Chiron Spa 741
GB0408977D0 (en) 2004-04-22 2004-05-26 Chiron Srl Immunising against meningococcal serogroup Y using proteins
GB0524066D0 (en) 2005-11-25 2006-01-04 Chiron Srl 741 ii
US9579372B2 (en) 2008-02-21 2017-02-28 Glaxosmithkline Biologicals Sa Meningococcal fHBP polypeptides
EP2631245A1 (en) 2008-03-10 2013-08-28 Children's Hospital & Research Center at Oakland Chimeric factor H binding proteins (fHBP) containing a heterologous B domain and methods of use
HRP20201076T1 (hr) 2009-03-24 2020-10-30 Glaxosmithkline Biologicals Sa Adjuvantni vezujući protein meningokokalnog faktora h
WO2010127172A2 (en) 2009-04-30 2010-11-04 Children's Hospital & Research Center At Oakland Chimeric factor h binding proteins (fhbp) and methods of use
AU2010310985B2 (en) * 2009-10-27 2014-11-06 Glaxosmithkline Biologicals S.A. Modified meningococcal fHBP polypeptides
US9567377B2 (en) * 2010-03-10 2017-02-14 Glaxosmithkline Biologicals Sa Immunogenic composition
ES2661569T3 (es) 2010-03-30 2018-04-02 Children's Hospital & Research Center At Oakland Proteínas de unión al factor H (fHbp) con propiedades alteradas y métodos de uso de las mismas
US10478483B2 (en) 2010-06-25 2019-11-19 Glaxosmithkline Biologicals Sa Combinations of meningococcal factor H binding proteins
ES2654613T3 (es) 2012-02-02 2018-02-14 Glaxosmithkline Biologicals Sa Promotores para una expresión aumentada de proteínas en meningococos
CN104602704B (zh) 2012-06-14 2019-08-06 诺华股份有限公司 针对血清组x脑膜炎球菌的疫苗
AU2013295242C1 (en) 2012-07-27 2018-08-09 Institut National De La Sante Et De La Recherche Medicale CD147 as receptor for pilus-mediated adhesion of meningococci to vascular endothelia
US20160030544A1 (en) * 2013-03-14 2016-02-04 Isis Innovation Limited Immunogenic composition to neisseria
JP2016527278A (ja) 2013-08-02 2016-09-08 チルドレンズ ホスピタル アンド リサーチ センター オークランド 天然に生じないh因子結合タンパク質(fhbp)及びその使用の方法
SG10201907875TA (en) 2014-02-28 2019-09-27 Glaxosmithkline Biologicals Sa Modified meningococcal fhbp polypeptides
ES2922554T3 (es) 2014-07-23 2022-09-16 Childrens Hospital & Res Center At Oakland Variantes de proteínas de unión al factor H y métodos de uso de las mismas
EP3183266B1 (en) * 2014-08-20 2019-05-29 Stichting Sanquin Bloedvoorziening Factor h potentiating antibodies and uses thereof
GB201614687D0 (en) * 2016-08-31 2016-10-12 Univ Oxford Innovation Ltd fHbp scaffold
EP3607967A1 (en) 2018-08-09 2020-02-12 GlaxoSmithKline Biologicals S.A. Modified meningococcal fhbp polypeptides
BR112021012250A2 (pt) 2018-12-21 2021-09-08 Griffith University Composições, métodos e usos para induzir uma resposta imune
EP3997108A4 (en) * 2019-07-08 2024-03-20 Crapaud Bio, Inc. METHODS OF PRODUCING AND USING LIPOOLIGOSACCHARIDE COMPOSITIONS AND VACCINES
EP3999073A4 (en) 2019-07-17 2023-07-26 Gemini Therapeutics Sub, Inc. Factor h potentiating antibodies and uses thereof
TW202245836A (zh) 2021-02-19 2022-12-01 美商賽諾菲巴斯德公司 重組b型腦膜炎球菌疫苗
TW202423477A (zh) 2022-08-03 2024-06-16 美商賽諾菲巴斯德公司 針對腦膜炎奈瑟氏菌b的含佐劑免疫原性組成物

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4786592A (en) * 1986-06-18 1988-11-22 Scripps Clinic And Research Foundation Neisseria gonorrhoeae lectin useful as a vaccine and diagnostic marker and means for producing this lectin
US5476784A (en) * 1993-04-06 1995-12-19 Rice; Peter A. Gonococcal anti-idiotypic antibodies and methods and compositions using them
GB0220194D0 (en) * 2002-08-30 2002-10-09 Chiron Spa Improved vesicles
MXPA05011110A (es) * 2003-04-16 2006-01-24 Wyeth Corp Composiciones inmunogenicas novedosas para la prevencion y tratamiento de un padecimiento originado por meningococos.
MX2007008785A (es) * 2005-01-27 2008-02-15 Childrens Hosp & Res Ct Oak Vacunas de vesicula basadas en gna1870 para proteccion de amplio espectro contra padecimientos causados por neisseria meningitidis.
GB0524066D0 (en) * 2005-11-25 2006-01-04 Chiron Srl 741 ii
AU2007263531B2 (en) * 2006-06-29 2012-03-15 J. Craig Venter Institute, Inc. Polypeptides from neisseria meningitidis
NZ622048A (en) * 2009-08-27 2015-10-30 Novartis Ag Hybrid polypeptides including meningococcal fhbp sequences
ES2661569T3 (es) * 2010-03-30 2018-04-02 Children's Hospital & Research Center At Oakland Proteínas de unión al factor H (fHbp) con propiedades alteradas y métodos de uso de las mismas

Also Published As

Publication number Publication date
AU2009306114A1 (en) 2010-04-29
PL3501534T3 (pl) 2024-04-02
JP2012506411A (ja) 2012-03-15
BRPI0919926A2 (pt) 2016-02-16
US20120052092A1 (en) 2012-03-01
JP2015063558A (ja) 2015-04-09
JP5676458B2 (ja) 2015-02-25
CN102245202A (zh) 2011-11-16
CN105412920A (zh) 2016-03-23
FI3501534T3 (fi) 2024-02-09
EP3501534B1 (en) 2023-11-29
KR20110092282A (ko) 2011-08-17
LT3501534T (lt) 2024-03-12
AU2009306114B2 (en) 2015-10-01
HUE065348T2 (hu) 2024-05-28
EP2355845B1 (en) 2018-12-05
NZ601538A (en) 2014-01-31
MX2011004322A (es) 2011-06-16
EP3501534A1 (en) 2019-06-26
NZ592444A (en) 2012-11-30
JP6076326B2 (ja) 2017-02-08
KR20170000390A (ko) 2017-01-02
EP2355845A1 (en) 2011-08-17
GB0819633D0 (en) 2008-12-03
DK3501534T5 (da) 2024-09-02
WO2010046715A1 (en) 2010-04-29
DK3501534T3 (da) 2024-02-05
CO6382140A2 (es) 2012-02-15
RU2559528C2 (ru) 2015-08-10
SI3501534T1 (sl) 2024-03-29
RU2011120706A (ru) 2012-11-27
HRP20240226T1 (hr) 2024-05-10
PT3501534T (pt) 2024-02-07
KR20190011836A (ko) 2019-02-07
CA2741619A1 (en) 2010-04-29

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