ES2967942T3 - Generación de células beta funcionales a partir de progenitoras endocrinas derivadas de células madre pluripotentes humanas - Google Patents
Generación de células beta funcionales a partir de progenitoras endocrinas derivadas de células madre pluripotentes humanas Download PDFInfo
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- ES2967942T3 ES2967942T3 ES17709385T ES17709385T ES2967942T3 ES 2967942 T3 ES2967942 T3 ES 2967942T3 ES 17709385 T ES17709385 T ES 17709385T ES 17709385 T ES17709385 T ES 17709385T ES 2967942 T3 ES2967942 T3 ES 2967942T3
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| SG181687A1 (en) | 2009-12-23 | 2012-07-30 | Centocor Ortho Biotech Inc | Differentiation of human embryonic stem cells |
| RU2663339C1 (ru) | 2010-05-12 | 2018-08-03 | Янссен Байотек, Инк. | Дифференцирование эмбриональных стволовых клеток человека |
| WO2012175633A1 (en) | 2011-06-21 | 2012-12-27 | Novo Nordisk A/S | Efficient induction of definitive endoderm from pluripotent stem cells |
| AU2013255031C1 (en) * | 2012-04-30 | 2018-12-06 | University Health Network | Methods and compositions for generating pancreatic progenitors and functional beta cells from hPSCs |
| EP2893000B1 (en) * | 2012-09-03 | 2019-04-10 | Novo Nordisk A/S | Generation of pancreatic endoderm from pluripotent stem cells using small molecules |
| EP2900820B2 (en) * | 2012-09-27 | 2020-11-18 | Institut National de la Sante et de la Recherche Medicale (INSERM) | Methods for producing a population of pancreatic beta-cells |
| JP6557147B2 (ja) | 2012-12-31 | 2019-08-07 | ヤンセン バイオテツク，インコーポレーテツド | Ｈｂ９調節物を用いたヒト胚性幹細胞の膵臓内分泌細胞への分化 |
| US20150368616A1 (en) * | 2013-02-14 | 2015-12-24 | The Cleveland Clinic Foundation | Methods for induction of cell fates from pluripotent cells |
| JP2016521971A (ja) | 2013-04-23 | 2016-07-28 | イェダ リサーチ アンド ディベロップメント カンパニー リミテッド | 単離ナイーブ型多能性幹細胞およびそれを発生させる方法関連出願本出願は、米国特許法１１９条第（ｅ）項に基づき、２０１４年１月２９日出願の米国特許仮出願第６１／９３２，９３５号、２０１３年９月１７日出願の米国特許仮出願第６１／８７８，７６９号、および２０１３年４月２３日出願の米国特許仮出願第６１／８１４，９２０号の優先権を主張する。また、本出願は、同時に提出された同出願人による同時係属出願である、ＹａｑｕｂＨＡＮＮＡ、ＮｏａＮＯＶＥＲＳＨＴＥＲＮ、およびＹｏａｃｈＲＡＩＳによる米国特許出願（発明の名称「単離ナイーブ型多能性幹細胞およびそれを発生させる方法（ＩＳＯＬＡＴＥＤＮＡＩＶＥＰＬＵＲＩＰＯＴＥＮＴＳＴＥＭＣＥＬＬＳＡＮＤＭＥＴＨＯＤＳＯＦＧＥＮＥＲＡＴＩＮＧＳＡＭＥ）」）（代理人事件記録簿第５８８７０号）にも関する。上記出願の内容はその全体を参考として本明細書に組み込む。 |
| WO2014179198A1 (en) | 2013-04-29 | 2014-11-06 | Wisconsin Alumni Research Foundation | Methods for producing insulin-secreting beta cells from human pluripotent stem cells |
| SG11201510177WA (en) * | 2013-06-11 | 2016-01-28 | Harvard College | SC-β CELLS AND COMPOSITIONS AND METHODS FOR GENERATING THE SAME |
| DK3039122T3 (da) | 2013-08-30 | 2019-09-30 | Novo Nordisk As | Generering af endokrine progenitorceller fra humane pluripotente stamceller under anvendelse af små molekyler |
| US20150250824A1 (en) * | 2014-03-07 | 2015-09-10 | The Research Foundation For The State University Of New York | Methods and compositions for expansion of stem cells and other cells |
| US10006006B2 (en) | 2014-05-16 | 2018-06-26 | Janssen Biotech, Inc. | Use of small molecules to enhance MAFA expression in pancreatic endocrine cells |
| WO2017144695A1 (en) | 2016-02-24 | 2017-08-31 | Novo Nordisk A/S | Generation of functional beta cells from human pluripotent stem cell-derived endocrine progenitors |
| AU2018439389A1 (en) | 2018-08-30 | 2021-02-18 | Novo Nordisk A/S | Generation of functional beta cells from human pluripotent stem cell-derived endocrine progenitors |
-
2017
- 2017-02-24 WO PCT/EP2017/054390 patent/WO2017144695A1/en not_active Ceased
- 2017-02-24 MA MA045747A patent/MA45747A/fr unknown
- 2017-02-24 ES ES17709385T patent/ES2967942T3/es active Active
- 2017-02-24 EP EP17709385.3A patent/EP3420073B1/en active Active
- 2017-02-24 JP JP2018544785A patent/JP7123802B2/ja active Active
- 2017-02-24 US US16/078,763 patent/US11274280B2/en active Active
- 2017-02-24 CN CN201780013255.3A patent/CN108699515A/zh active Pending
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|---|---|
| WO2017144695A1 (en) | 2017-08-31 |
| EP3420073C0 (en) | 2023-11-08 |
| MA45747A (fr) | 2019-01-02 |
| JP2019510482A (ja) | 2019-04-18 |
| WO2017144695A9 (en) | 2017-10-19 |
| CN108699515A (zh) | 2018-10-23 |
| US20190085295A1 (en) | 2019-03-21 |
| EP3420073A1 (en) | 2019-01-02 |
| JP7123802B2 (ja) | 2022-08-23 |
| EP3420073B1 (en) | 2023-11-08 |
| US11274280B2 (en) | 2022-03-15 |
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