ES2959183T3 - Derivados de manosa y su uso en el tratamiento de infecciones bacterianas - Google Patents
Derivados de manosa y su uso en el tratamiento de infecciones bacterianas Download PDFInfo
- Publication number
- ES2959183T3 ES2959183T3 ES14804252T ES14804252T ES2959183T3 ES 2959183 T3 ES2959183 T3 ES 2959183T3 ES 14804252 T ES14804252 T ES 14804252T ES 14804252 T ES14804252 T ES 14804252T ES 2959183 T3 ES2959183 T3 ES 2959183T3
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- heterocycle
- aryl
- optionally substituted
- cycloalkyl
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Classifications
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- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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Landscapes
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Applications Claiming Priority (2)
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|---|---|---|---|
| US201361828954P | 2013-05-30 | 2013-05-30 | |
| PCT/US2014/040355 WO2014194270A1 (en) | 2013-05-30 | 2014-05-30 | Compounds and methods for treating bacterial infections |
Publications (1)
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| ES2959183T3 true ES2959183T3 (es) | 2024-02-21 |
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| ES14804252T Active ES2959183T3 (es) | 2013-05-30 | 2014-05-30 | Derivados de manosa y su uso en el tratamiento de infecciones bacterianas |
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| Country | Link |
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| US (4) | US9957289B2 (OSRAM) |
| EP (1) | EP3003322B1 (OSRAM) |
| JP (2) | JP6640716B2 (OSRAM) |
| CN (2) | CN111423479A (OSRAM) |
| AU (1) | AU2014273962B2 (OSRAM) |
| CA (1) | CA2913622A1 (OSRAM) |
| ES (1) | ES2959183T3 (OSRAM) |
| HK (1) | HK1225649A1 (OSRAM) |
| WO (1) | WO2014194270A1 (OSRAM) |
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| GB2463181B (en) | 2007-05-14 | 2013-03-27 | Univ New York State Res Found | Induction of a physiological dispersion response in bacterial cells in a biofilm |
| WO2012109263A1 (en) | 2011-02-07 | 2012-08-16 | The Washington University | Mannoside compounds and methods of use thereof |
| ES2959183T3 (es) | 2013-05-30 | 2024-02-21 | Washington University St Louis | Derivados de manosa y su uso en el tratamiento de infecciones bacterianas |
| EP3300500B9 (en) | 2015-05-20 | 2021-01-13 | Amgen Inc. | Triazole agonists of the apj receptor |
| ES2899906T3 (es) | 2015-07-06 | 2022-03-15 | Alkermes Inc | Inhibidores bicíclicos de histona desacetilasa |
| EP3319968A1 (en) | 2015-07-06 | 2018-05-16 | Rodin Therapeutics, Inc. | Heterobicyclic n-aminophenyl-amides as inhibitors of histone deacetylase |
| JP6961572B2 (ja) * | 2015-08-05 | 2021-11-05 | アンテローム | 付着性大腸菌と関連する病状の処置に有用なマンノース誘導体 |
| US20200002303A1 (en) * | 2016-03-11 | 2020-01-02 | Fimbrion Therapeutics, Inc. | C-glycoside compounds useful for treating disease |
| KR20180128937A (ko) * | 2016-03-23 | 2018-12-04 | 핌브리온 세러퓨틱스 인코포레이티드 | 질환을 치료하는데 유용한 fimh의 만노스-유래 길항제 |
| WO2017192485A1 (en) | 2016-05-03 | 2017-11-09 | Amgen Inc. | Heterocyclic triazole compounds as agonists of the apj receptor |
| EP3541810B1 (en) | 2016-11-16 | 2020-12-23 | Amgen Inc. | Triazole phenyl compounds as agonists of the apj receptor |
| EP3541802B1 (en) | 2016-11-16 | 2025-01-01 | Amgen Inc. | Alkyl substituted triazole compounds as agonists of the apj receptor |
| WO2018093577A1 (en) | 2016-11-16 | 2018-05-24 | Amgen Inc. | Cycloalkyl substituted triazole compounds as agonists of the apj receptor |
| WO2018097944A1 (en) | 2016-11-16 | 2018-05-31 | Amgen Inc. | Triazole furan compounds as agonists of the apj receptor |
| US11046680B1 (en) | 2016-11-16 | 2021-06-29 | Amgen Inc. | Heteroaryl-substituted triazoles as APJ receptor agonists |
| US10689367B2 (en) | 2016-11-16 | 2020-06-23 | Amgen Inc. | Triazole pyridyl compounds as agonists of the APJ receptor |
| ES2875562T3 (es) | 2017-01-11 | 2021-11-10 | Alkermes Inc | Inhibidores bicíclicos de histona desacetilasa |
| US11225475B2 (en) | 2017-08-07 | 2022-01-18 | Alkermes, Inc. | Substituted pyridines as inhibitors of histone deacetylase |
| JP2021500921A (ja) | 2017-10-16 | 2021-01-14 | アンテローム | Ｆｉｍｈ遮断剤の治療効率を評価するための新規ツール |
| US11149040B2 (en) | 2017-11-03 | 2021-10-19 | Amgen Inc. | Fused triazole agonists of the APJ receptor |
| WO2019213006A1 (en) | 2018-05-01 | 2019-11-07 | Amgen Inc. | Substituted pyrimidinones as agonists of the apj receptor |
| DK3820856T3 (da) * | 2018-07-10 | 2022-10-24 | Glaxosmithkline Ip Dev Ltd | C-Mannosid-forbindelser, der kan anvendes til behandling af urinvejsinfektioner |
| CN109762034B (zh) * | 2019-02-23 | 2022-04-29 | 福建医科大学 | 新型对苯二甲醛缩d-氨基葡萄糖席夫碱的制备方法 |
| BR112021022281A2 (pt) * | 2019-05-07 | 2021-12-28 | Fimbrion Therapeutics Inc | Novos compostos |
| WO2020254369A1 (en) * | 2019-06-19 | 2020-12-24 | Glaxosmithkline Intellectual Property Development Limited | Substituted biphenyl or phenylheteroaryl-mannosides as antagonists of fimh |
| CN115361953A (zh) * | 2020-03-02 | 2022-11-18 | N·帕特尔 | 一种药物组合物和使用舍雷肽酶、甘露糖或其衍生物、以及任选存在的抗感染剂的治疗方法 |
| CN113461753B (zh) * | 2020-03-31 | 2023-05-23 | 郑计岳 | 2-炔基甘露糖衍生物及其应用 |
| CN113797212B (zh) * | 2020-06-11 | 2023-12-22 | 兰州大学 | 一组含有甘露糖结构的抗菌药物的合成方法及活性研究 |
| WO2022146994A1 (en) | 2020-12-28 | 2022-07-07 | Georgia Tech Research Corporation | Glycosylated histone deacetylase inhibitors and methods of making and using the same |
| US12116382B2 (en) | 2022-11-28 | 2024-10-15 | Hongene Biotech Corporation | Functionalized N-acetylgalactosamine analogs |
| CN116023273A (zh) * | 2023-03-29 | 2023-04-28 | 思合基因(北京)生物科技有限公司 | 一种新型碳糖苷及其制备方法 |
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| US5122602A (en) | 1989-02-13 | 1992-06-16 | Miles Inc. | Chromogenic merocyanine enzyme substrates |
| US6420127B1 (en) | 1994-11-18 | 2002-07-16 | Washington University | Compounds and pharmaceutical compositions for the treatment and prophylaxis of bacterial infections |
| DE69433901T2 (de) | 1993-11-18 | 2005-07-28 | Siga Technologies, Inc. | Verbindungen und pharmazeutische zusammensetzungen zur behandlung und prophylaxe bakterieller infektionen |
| WO2001010386A2 (en) | 1999-08-11 | 2001-02-15 | Washington University | Anti-bacterial compounds directed against pilus biogenesis, adhesion and activity; co-crystals of pilus subunits and methods of use thereof |
| CA2411944C (en) | 2000-06-09 | 2010-12-14 | Baylor College Of Medicine | The combination of antimicrobial agents and bacterial interference to coat medical devices |
| WO2005033059A1 (es) | 2003-10-08 | 2005-04-14 | Innovaprotean, S.L. | Compuestos útiles para el tratamiento de enfermedades asociadas a la formación de fibrilas amiloides |
| EP1755619A2 (en) | 2004-03-23 | 2007-02-28 | VIB vzw | Anti-adhesive compounds to prevent and treat bacterial infections |
| SE528382C2 (sv) | 2004-10-05 | 2006-10-31 | Probi Ab | Probiotiska lactobacillusstammar för förbättrad vaginal hälsa |
| FR2876798A1 (fr) * | 2004-10-14 | 2006-04-21 | Univ Clermont Auvergne | Diagnostic et traitement de la maladie de crohn |
| EP2490530A4 (en) | 2009-10-22 | 2014-01-22 | Univ Washington | COMPOUNDS AND METHOD FOR THE TREATMENT OF BACTERIAL INFECTIONS |
| WO2012109263A1 (en) | 2011-02-07 | 2012-08-16 | The Washington University | Mannoside compounds and methods of use thereof |
| NZ616764A (en) * | 2009-12-14 | 2014-11-28 | Univ Basel | Mannose derivatives as antagonists of bacterial adhesion |
| WO2012164074A1 (en) | 2011-06-03 | 2012-12-06 | University Of Basel | Mannose phosphate derivatives as antagonists of bacterial adhesion |
| ES2959183T3 (es) | 2013-05-30 | 2024-02-21 | Washington University St Louis | Derivados de manosa y su uso en el tratamiento de infecciones bacterianas |
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| US20210122776A1 (en) | 2021-04-29 |
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| AU2014273962B2 (en) | 2019-07-25 |
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| US9957289B2 (en) | 2018-05-01 |
| JP2016520618A (ja) | 2016-07-14 |
| JP6640716B2 (ja) | 2020-02-05 |
| HK1223546A1 (en) | 2017-08-04 |
| CA2913622A1 (en) | 2014-12-04 |
| CN105682665A (zh) | 2016-06-15 |
| JP2020073543A (ja) | 2020-05-14 |
| US20160145289A1 (en) | 2016-05-26 |
| HK1225649A1 (zh) | 2017-09-15 |
| CN111423479A (zh) | 2020-07-17 |
| WO2014194270A1 (en) | 2014-12-04 |
| US20230033327A1 (en) | 2023-02-02 |
| EP3003322A1 (en) | 2016-04-13 |
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