ES2953044T3 - Análogos de pantotenamida - Google Patents

Análogos de pantotenamida Download PDF

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Publication number
ES2953044T3
ES2953044T3 ES19829246T ES19829246T ES2953044T3 ES 2953044 T3 ES2953044 T3 ES 2953044T3 ES 19829246 T ES19829246 T ES 19829246T ES 19829246 T ES19829246 T ES 19829246T ES 2953044 T3 ES2953044 T3 ES 2953044T3
Authority
ES
Spain
Prior art keywords
compound
propyl
acid
pantothenamide
tetramethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES19829246T
Other languages
English (en)
Spanish (es)
Inventor
Josephus Schalkwijk
Pedro Harold Han Hermkens
Koen Jakob Dechering
Roger Victor Bonnert
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MMV Medicines for Malaria Venture
Original Assignee
MMV Medicines for Malaria Venture
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MMV Medicines for Malaria Venture filed Critical MMV Medicines for Malaria Venture
Application granted granted Critical
Publication of ES2953044T3 publication Critical patent/ES2953044T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/04Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C235/10Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by nitrogen atoms not being part of nitro or nitroso groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06Antimalarials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • C07C255/49Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C255/58Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton
    • C07C255/60Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton at least one of the singly-bound nitrogen atoms being acylated
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ES19829246T 2018-12-31 2019-12-30 Análogos de pantotenamida Active ES2953044T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP18215980.6A EP3674288A1 (en) 2018-12-31 2018-12-31 Pantothenamide analogues
PCT/EP2019/087147 WO2020141155A1 (en) 2018-12-31 2019-12-30 Pantothenamide analogues

Publications (1)

Publication Number Publication Date
ES2953044T3 true ES2953044T3 (es) 2023-11-07

Family

ID=64949100

Family Applications (1)

Application Number Title Priority Date Filing Date
ES19829246T Active ES2953044T3 (es) 2018-12-31 2019-12-30 Análogos de pantotenamida

Country Status (7)

Country Link
US (2) US11572336B2 (https=)
EP (2) EP3674288A1 (https=)
JP (1) JP7423088B2 (https=)
CN (1) CN113286778B (https=)
CA (1) CA3125354C (https=)
ES (1) ES2953044T3 (https=)
WO (1) WO2020141155A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3674288A1 (en) 2018-12-31 2020-07-01 MMV Medicines for Malaria Venture Pantothenamide analogues
WO2023137529A1 (en) * 2022-01-24 2023-07-27 Australian National University Anti-parasite compounds

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000035296A1 (en) 1996-11-27 2000-06-22 Wm. Wrigley Jr. Company Improved release of medicament active agents from a chewing gum coating
WO2011152720A1 (en) 2010-05-31 2011-12-08 Umc St. Radboud Pantothenic acid derivatives and their use in the treatment of microbial infections
US20130345270A1 (en) 2010-11-12 2013-12-26 Waake Forest University Health Sciences Methods of treating cancer and other disorders
EP3215496B1 (en) 2014-11-06 2019-01-02 Radboud Universitair Medisch Centrum Pantothenamide analogues
WO2017066763A1 (en) * 2015-10-15 2017-04-20 Cornell University Proteasome inhibitors and uses thereof
EP3674288A1 (en) 2018-12-31 2020-07-01 MMV Medicines for Malaria Venture Pantothenamide analogues

Also Published As

Publication number Publication date
JP7423088B2 (ja) 2024-01-29
US20230159437A1 (en) 2023-05-25
US11834391B2 (en) 2023-12-05
BR112021011875A2 (pt) 2021-09-08
US11572336B2 (en) 2023-02-07
EP3906225A1 (en) 2021-11-10
EP3674288A1 (en) 2020-07-01
EP3906225C0 (en) 2023-07-05
BR122023026497A2 (pt) 2024-01-30
CN113286778B (zh) 2023-09-22
EP3906225B1 (en) 2023-07-05
CA3125354C (en) 2025-03-11
CN113286778A (zh) 2021-08-20
WO2020141155A1 (en) 2020-07-09
JP2022515549A (ja) 2022-02-18
US20220073450A1 (en) 2022-03-10
CA3125354A1 (en) 2020-07-09

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