ES2951287T3 - Método para controlar la formación del color rosa durante la fabricación de anticuerpos - Google Patents
Método para controlar la formación del color rosa durante la fabricación de anticuerpos Download PDFInfo
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- ES2951287T3 ES2951287T3 ES18734651T ES18734651T ES2951287T3 ES 2951287 T3 ES2951287 T3 ES 2951287T3 ES 18734651 T ES18734651 T ES 18734651T ES 18734651 T ES18734651 T ES 18734651T ES 2951287 T3 ES2951287 T3 ES 2951287T3
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
- C12N5/12—Fused cells, e.g. hybridomas
- C12N5/16—Animal cells
- C12N5/163—Animal cells one of the fusion partners being a B or a T lymphocyte
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
- C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/999—Small molecules not provided for elsewhere
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2511/00—Cells for large scale production
Landscapes
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- Organic Chemistry (AREA)
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- Genetics & Genomics (AREA)
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- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
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- Biomedical Technology (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
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| US201762503615P | 2017-05-09 | 2017-05-09 | |
| PCT/US2018/031542 WO2018208743A1 (en) | 2017-05-09 | 2018-05-08 | Method of controlling the formation of pink color during antibody manufacturing |
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|---|---|
| ES2951287T3 true ES2951287T3 (es) | 2023-10-19 |
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| BR112022012467A2 (pt) | 2020-01-31 | 2022-09-06 | Chugai Pharmaceutical Co Ltd | Método para produção de composição contendo polipeptídeo com coloração suprimida |
| JP2025529484A (ja) * | 2022-09-15 | 2025-09-04 | サノフイ | タンパク質の還元感受性の決定方法 |
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| JP2689458B2 (ja) * | 1988-02-09 | 1997-12-10 | 武田薬品工業株式会社 | 粒状ないし粉末状のビタミンｂ▲下１▼▲下２▼類含有組成物 |
| JP2734709B2 (ja) * | 1990-01-05 | 1998-04-02 | 東レ株式会社 | インクジェット染色用布帛およびそれを用いてなるインクジェット染色法 |
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| WO2006060083A1 (en) * | 2004-10-22 | 2006-06-08 | Amgen Inc. | Methods for refolding polypeptides |
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| EP2453874A2 (en) | 2009-07-14 | 2012-05-23 | Biogen Idec MA Inc. | Methods for inhibiting yellow color and peroxide formation in a composition |
| US20170002393A1 (en) * | 2013-12-04 | 2017-01-05 | Immunogen, Inc. | Compositions and methods for antibody production |
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| EP3621989A1 (en) | 2020-03-18 |
| EP3621989B1 (en) | 2023-06-28 |
| JP7453788B2 (ja) | 2024-03-21 |
| JP2020519265A (ja) | 2020-07-02 |
| US20230103511A1 (en) | 2023-04-06 |
| CN110831964A (zh) | 2020-02-21 |
| JP2023182593A (ja) | 2023-12-26 |
| WO2018208743A9 (en) | 2019-12-05 |
| KR20200004355A (ko) | 2020-01-13 |
| US12241107B2 (en) | 2025-03-04 |
| KR102664829B1 (ko) | 2024-05-09 |
| WO2018208743A1 (en) | 2018-11-15 |
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