ES2948767T3 - Moléculas orgánicas pequeñas para uso en el tratamiento de trastornos neuroinflamatorios - Google Patents
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| MY109202A (en) | 1992-07-10 | 1996-12-31 | Nihon Nohyaku Co Ltd | Isothiazole derivatives and processes for preparing the same as well as termite controlling agents comprising the same as active ingredient |
| IT1313601B1 (it) | 1999-08-05 | 2002-09-09 | Isagro Ricerca Srl | Fenilpirazoli ad attivita' erbicida |
| EP1088822A1 (en) * | 1999-09-28 | 2001-04-04 | Applied Research Systems ARS Holding N.V. | Pharmaceutically active sulfonyl hydrazide derivatives |
| US6989451B2 (en) * | 2002-06-04 | 2006-01-24 | Valeant Research & Development | Heterocyclic compounds and uses thereof |
| US6727241B2 (en) | 2002-06-12 | 2004-04-27 | Chemocentryx | Anti-inflammatory compositions and methods of use |
| GB0306357D0 (en) | 2003-03-20 | 2003-04-23 | Astrazeneca Ab | Chemical compounds |
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| US20060217390A1 (en) | 2005-02-24 | 2006-09-28 | Esmir Gunic | Cycloalkl, aryl and heteroaryl amino isothiazoles for the treatment of Hepatitis C virus |
| WO2006124874A2 (en) | 2005-05-12 | 2006-11-23 | Kalypsys, Inc. | Inhibitors of b-raf kinase |
| CN100396667C (zh) * | 2006-02-20 | 2008-06-25 | 中国医学科学院医药生物技术研究所 | 一组具有上调骨形成蛋白bmp-2表达活性的五元不饱和杂环化合物 |
| US8497272B2 (en) | 2006-08-21 | 2013-07-30 | Synta Pharmaceuticals Corp. | Compounds for treating proliferative disorders |
| WO2008118626A2 (en) | 2007-03-08 | 2008-10-02 | Burnham Institute For Medical Research | Inhibitors of jnk and methods for identifying inhibitors of jnk |
| CA2718403A1 (en) * | 2008-03-13 | 2009-09-17 | The General Hospital Corporation | Inhibitors of the bmp signaling pathway |
| WO2011008640A1 (en) * | 2009-07-14 | 2011-01-20 | Beth Israel Deaconess Medical Center, Inc. | Methods of increasing liver proliferation |
| KR20120081585A (ko) | 2009-08-11 | 2012-07-19 | 알러간, 인코포레이티드 | 안질환을 치료하기 위한 이소티오졸 |
| JP5725469B2 (ja) * | 2010-11-15 | 2015-05-27 | 学校法人北里研究所 | 骨分化阻害剤およびその製造方法 |
| WO2013186777A2 (en) * | 2012-06-14 | 2013-12-19 | The Medical Researth, Infrastructure, And Health Services Fund Of The Tel Aviv Medical Center | Use of blocking agents of bone morphogenie protein (bmp) signaling for the treatment of neuroinflammatory and neurodegenerative diseases |
| JP6542192B2 (ja) * | 2013-03-14 | 2019-07-10 | ザ ブリガム アンド ウィメンズ ホスピタル インコーポレイテッドＴｈｅ Ｂｒｉｇｈａｍ ａｎｄ Ｗｏｍｅｎ’ｓ Ｈｏｓｐｉｔａｌ， Ｉｎｃ． | Ｂｍｐ阻害剤およびその使用方法 |
| JP6543342B2 (ja) | 2014-08-14 | 2019-07-10 | アルハマドシャー，マモウン，エム． | 血清半減期を延長するための、調節可能リンカーを介した薬学的活性剤とトランスサイレチンリガンドのコンジュゲーション |
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2017
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| CA3061296A1 (en) | 2018-11-01 |
| US20200046680A1 (en) | 2020-02-13 |
| US11779565B2 (en) | 2023-10-10 |
| IL251949A0 (en) | 2017-07-31 |
| EP3615022C0 (en) | 2023-06-07 |
| AU2018260535B2 (en) | 2023-09-28 |
| US20210393582A1 (en) | 2021-12-23 |
| EP3615022A4 (en) | 2021-03-31 |
| US11103479B2 (en) | 2021-08-31 |
| CN110869015B (zh) | 2023-08-18 |
| CN110869015A (zh) | 2020-03-06 |
| JP2020517678A (ja) | 2020-06-18 |
| JP6997800B2 (ja) | 2022-02-04 |
| EP3615022B1 (en) | 2023-06-07 |
| WO2018198123A1 (en) | 2018-11-01 |
| AU2018260535A1 (en) | 2019-10-31 |
| IL269894B (en) | 2022-03-01 |
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