ES2936394T3 - Métodos y composiciones para tratar la enfermedad del ojo seco y otros trastornos oculares - Google Patents
Métodos y composiciones para tratar la enfermedad del ojo seco y otros trastornos oculares Download PDFInfo
- Publication number
- ES2936394T3 ES2936394T3 ES16756227T ES16756227T ES2936394T3 ES 2936394 T3 ES2936394 T3 ES 2936394T3 ES 16756227 T ES16756227 T ES 16756227T ES 16756227 T ES16756227 T ES 16756227T ES 2936394 T3 ES2936394 T3 ES 2936394T3
- Authority
- ES
- Spain
- Prior art keywords
- alpha
- ophthalmic
- dry eye
- pharmaceutical formulation
- brimonidine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/04—Artificial tears; Irrigation solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Ophthalmology & Optometry (AREA)
- Dispersion Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562119857P | 2015-02-24 | 2015-02-24 | |
| PCT/US2016/019207 WO2016138049A1 (en) | 2015-02-24 | 2016-02-23 | Methods and compositions for treating dry eye disease and other eye disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2936394T3 true ES2936394T3 (es) | 2023-03-16 |
Family
ID=56692824
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES16756227T Active ES2936394T3 (es) | 2015-02-24 | 2016-02-23 | Métodos y composiciones para tratar la enfermedad del ojo seco y otros trastornos oculares |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US9597328B2 (enExample) |
| EP (1) | EP3261620B1 (enExample) |
| JP (1) | JP2018506570A (enExample) |
| KR (1) | KR20170132725A (enExample) |
| CN (1) | CN107427459A (enExample) |
| AU (1) | AU2016222902A1 (enExample) |
| BR (1) | BR112017017448A2 (enExample) |
| CA (1) | CA2976120A1 (enExample) |
| ES (1) | ES2936394T3 (enExample) |
| MX (1) | MX2017010544A (enExample) |
| RU (1) | RU2691412C2 (enExample) |
| WO (1) | WO2016138049A1 (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20080114423A1 (en) | 2006-05-15 | 2008-05-15 | Grenon Stephen M | Apparatus for inner eyelid treatment of meibomian gland dysfunction |
| US7981145B2 (en) | 2005-07-18 | 2011-07-19 | Tearscience Inc. | Treatment of meibomian glands |
| US20070060988A1 (en) | 2005-07-18 | 2007-03-15 | Grenon Stephen M | Melting meibomian gland obstructions |
| US8083787B2 (en) | 2005-07-18 | 2011-12-27 | Tearscience, Inc. | Method and apparatus for treating meibomian gland dysfunction |
| US20170232024A1 (en) | 2014-08-04 | 2017-08-17 | Jerry Tan Eye Surgery Pte Ltd | Pharmaceutical compositions for demodex related blepharitis and eyelid crusting |
| US11478437B2 (en) * | 2016-07-05 | 2022-10-25 | Jenivision Inc. | Formulations for hair growth |
| CN110996904A (zh) * | 2017-05-19 | 2020-04-10 | 奥古根有限公司 | 眼用组合物及使用方法 |
| CA3080166A1 (en) * | 2017-11-21 | 2019-05-31 | Axerovision, Inc. | Compositions and methods of use for treating aberrant inflammation in peri-ocular secretory glands or at the ocular surface |
| CN119157876A (zh) * | 2017-12-15 | 2024-12-20 | 塔苏斯制药有限公司 | 用于治疗睑炎的异恶唑啉驱虫剂制剂和方法 |
| WO2019189720A1 (ja) * | 2018-03-30 | 2019-10-03 | 千寿製薬株式会社 | 水性液剤 |
| WO2019189721A1 (ja) * | 2018-03-30 | 2019-10-03 | 千寿製薬株式会社 | 水性液剤 |
| US11077053B2 (en) | 2018-08-21 | 2021-08-03 | Allergan, Inc. | Alpha-2-adrenergic receptor agonists for treatment of presbyopia, visual glare, visual starbursts, visual halos and night myopia |
| WO2020047197A1 (en) * | 2018-08-29 | 2020-03-05 | Ocugen, Inc. | Ophthalmic compositions and methods of use |
| US12502377B2 (en) | 2019-04-04 | 2025-12-23 | Tarsus Pharmaceuticals, Inc. | Method of eradicating ticks that attach to humans using lotilaner formulations |
| BR112022011067A2 (pt) * | 2019-12-10 | 2022-08-23 | Alcon Inc | Insertos oculares poliméricos dissolvíveis com um polímero biodegradável |
| WO2022031830A1 (en) * | 2020-08-04 | 2022-02-10 | Harrow Ip Llc | Antibacterial compositions and methods for fabricating thereof |
| CN116710087A (zh) * | 2020-11-23 | 2023-09-05 | 美国商业眼科医疗器械公司 | 用于治疗眼部病症的制剂和方法 |
| US20220160668A1 (en) | 2020-11-23 | 2022-05-26 | Sight Sciences, Inc. | Formulations and methods for treating conditions of the eye |
| EP4085891A1 (en) * | 2021-05-05 | 2022-11-09 | B. Braun Melsungen AG | Dexmedetomidine-solution in a low-density polyethylene container |
| CN115645356A (zh) * | 2022-11-21 | 2023-01-31 | 山东诺明康药物研究院有限公司 | 一种酒石酸溴莫尼定原位凝胶及其制备方法和应用 |
| WO2025174723A1 (en) * | 2024-02-12 | 2025-08-21 | Selagine Inc. | Ophthalmic composition comprising cethromycin |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SK3412U (sk) * | 2002-07-01 | 2003-01-09 | Unimed Pharma Spol Sro | Očná inštalácia so zlepšenou stabilitou účinnej látky na báze brimomidínu |
| US20040088199A1 (en) * | 2002-10-31 | 2004-05-06 | Childress Allen B. | Method of forming a business rule |
| US20050196370A1 (en) * | 2003-03-18 | 2005-09-08 | Zhi-Jian Yu | Stable ophthalmic oil-in-water emulsions with sodium hyaluronate for alleviating dry eye |
| JP2007528897A (ja) * | 2004-03-12 | 2007-10-18 | メルビ ホールディングス， エルエルシー | 眼表面用の潤滑剤 |
| WO2008011836A2 (es) * | 2006-07-25 | 2008-01-31 | Osmotica Corp. | Soluciones oftálmicas |
| US9125807B2 (en) * | 2007-07-09 | 2015-09-08 | Incept Llc | Adhesive hydrogels for ophthalmic drug delivery |
| CN101352441A (zh) * | 2007-07-27 | 2009-01-28 | 肖正连 | 一种酒石酸溴莫尼定眼用即型凝胶 |
| US20120003296A1 (en) * | 2010-07-01 | 2012-01-05 | Shantha Totada R | New methods of treating dry eye syndrome |
| KR101847669B1 (ko) * | 2010-08-16 | 2018-05-24 | 알러간, 인코포레이티드 | 알파-2b 아드레날린성 수용체 효현제로 조절 t 세포를 활성화시키는 방법 |
| US20120082625A1 (en) * | 2010-09-28 | 2012-04-05 | Michael Graeber | Combination treatment for rosacea |
| US20120076738A1 (en) * | 2010-09-28 | 2012-03-29 | Michael Graeber | Combination treatment for dermatological conditions |
| US20120093876A1 (en) * | 2010-10-13 | 2012-04-19 | Aciex, Inc. | Ophthalmic Formulations, Methods Of Manufacture And Methods of Normalizing Meibomian Gland Secretions |
| EP2694048B1 (en) * | 2011-04-05 | 2020-10-07 | Optosolve Research & Development Ltd | Ophthalmic treatments |
| EP2630952A1 (en) * | 2012-02-23 | 2013-08-28 | Novagali Pharma S.A. | Self-preserved oil dispersions comprising boric acid |
-
2016
- 2016-02-23 US US15/051,654 patent/US9597328B2/en active Active
- 2016-02-23 KR KR1020177023704A patent/KR20170132725A/ko not_active Withdrawn
- 2016-02-23 JP JP2017545544A patent/JP2018506570A/ja active Pending
- 2016-02-23 CA CA2976120A patent/CA2976120A1/en active Pending
- 2016-02-23 EP EP16756227.1A patent/EP3261620B1/en active Active
- 2016-02-23 AU AU2016222902A patent/AU2016222902A1/en not_active Abandoned
- 2016-02-23 ES ES16756227T patent/ES2936394T3/es active Active
- 2016-02-23 WO PCT/US2016/019207 patent/WO2016138049A1/en not_active Ceased
- 2016-02-23 CN CN201680011749.3A patent/CN107427459A/zh active Pending
- 2016-02-23 BR BR112017017448A patent/BR112017017448A2/pt not_active Application Discontinuation
- 2016-02-23 MX MX2017010544A patent/MX2017010544A/es unknown
- 2016-02-23 RU RU2017129247A patent/RU2691412C2/ru active
Also Published As
| Publication number | Publication date |
|---|---|
| US9597328B2 (en) | 2017-03-21 |
| AU2016222902A1 (en) | 2017-08-31 |
| JP2018506570A (ja) | 2018-03-08 |
| RU2017129247A3 (enExample) | 2019-03-25 |
| EP3261620B1 (en) | 2022-11-09 |
| KR20170132725A (ko) | 2017-12-04 |
| RU2017129247A (ru) | 2019-03-25 |
| RU2691412C2 (ru) | 2019-06-13 |
| WO2016138049A1 (en) | 2016-09-01 |
| EP3261620A4 (en) | 2018-10-31 |
| BR112017017448A2 (pt) | 2018-04-03 |
| MX2017010544A (es) | 2018-06-18 |
| CN107427459A (zh) | 2017-12-01 |
| EP3261620A1 (en) | 2018-01-03 |
| US20160243116A1 (en) | 2016-08-25 |
| CA2976120A1 (en) | 2016-09-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP3261620B1 (en) | Methods and compositions for treating dry eye disease and other eye disorders | |
| JP7796783B2 (ja) | 眼周囲分泌腺におけるまたは眼表面での異常な炎症を処置するための組成物および使用方法 | |
| US10555947B2 (en) | Ophthalmic compositions and methods of use | |
| US20080233053A1 (en) | Method and Device for Ophthalmic Administration of Active Pharmaceutical Ingredients | |
| EP2493474A2 (en) | Methods and compositions for sustained delivery of drugs | |
| US20190008920A1 (en) | Ophthalmic compositions and methods of use | |
| CN113473970A (zh) | 用以治疗眼表疾病的眼科药物组合物和方法 | |
| KR20230058444A (ko) | 코, 귀 및 다른 조직 감염 및/또는 염증을 치료하기 위한 조성물, 디바이스 및 방법 | |
| JP7397910B2 (ja) | 一酸化窒素放出プロスタミドを含有する眼科用組成物 | |
| EP3727335A1 (en) | Ocular drug delivery | |
| US10751337B2 (en) | Preservative free ocular compositions and methods for using the same for treating dry eye disease and other eye disorders | |
| US20110118226A1 (en) | Transdermal pharmaceutical compositions comprising danazol | |
| US20180221278A1 (en) | Prsustained release opthalmic formuation and methods for using the same | |
| CN101123948A (zh) | 眼科用固体外用药剂 | |
| US9877964B2 (en) | Methods and compositions for treating dry eye disease and other eye disorders | |
| EP3843721A1 (en) | Ophthalmic compositions and methods of use | |
| EP4268827A1 (en) | Pharmaceutical composition for topical administration containing epinastine or salt thereof | |
| CA3115664C (en) | Ophthalmic compositions and methods of use | |
| HK40091801A (en) | Pharmaceutical composition for topical administration containing epinastine or salt thereof | |
| HK40097614A (en) | Pharmaceutical composition for topical administration containing epinastine or salt thereof | |
| CN116669705A (zh) | 含有依匹斯汀或其盐的涂布施予用医药组合物 | |
| HK40031931A (en) | Oxymetazoline compositions and methods for treating ocular disorders | |
| HK40018890A (en) | Ophthalmic compositions containing a nitric oxide releasing prostamide | |
| HK40018890B (en) | Ophthalmic compositions containing a nitric oxide releasing prostamide |