ES2932441T3 - Formas cristalinas y procesos para la preparación de azaciclos condensados (moduladores de los receptores cannabinoides) - Google Patents
Formas cristalinas y procesos para la preparación de azaciclos condensados (moduladores de los receptores cannabinoides) Download PDFInfo
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- ES2932441T3 ES2932441T3 ES18164225T ES18164225T ES2932441T3 ES 2932441 T3 ES2932441 T3 ES 2932441T3 ES 18164225 T ES18164225 T ES 18164225T ES 18164225 T ES18164225 T ES 18164225T ES 2932441 T3 ES2932441 T3 ES 2932441T3
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- hydroxymethyl
- pentalene
- amide
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4965—Non-condensed pyrazines
- A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
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- A—HUMAN NECESSITIES
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- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
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| US9597340B2 (en) | 2011-02-25 | 2017-03-21 | Arena Pharmaceuticals, Inc. | Cannabinoid receptor modulators |
| MX392150B (es) | 2011-02-25 | 2025-03-21 | Arena Pharm Inc | Moduladores de receptores canabinoides. |
| JP5945554B2 (ja) * | 2011-02-25 | 2016-07-05 | アリーナ ファーマシューティカルズ， インコーポレイテッド | 縮合型アザ環の結晶形およびその調製プロセス（カンナビノイド受容体モジュレーター） |
| WO2016085941A1 (en) * | 2014-11-25 | 2016-06-02 | Arena Pharmaceuticals, Inc. | Processes for the preparation of cannabinoid receptor modulators |
| CN109310673A (zh) * | 2016-04-10 | 2019-02-05 | 艾尼纳制药公司 | 用选择性cb2受体激动剂治疗的方法 |
| WO2018208847A1 (en) | 2017-05-08 | 2018-11-15 | Arena Pharmaceuticals, Inc. | Compounds and methods for treatment of pain from inflammatory bowel disease |
| US20200078358A1 (en) * | 2017-05-08 | 2020-03-12 | Arena Pharmaceuticals, Inc. | Compounds and Methods for Treatment of Visceral Pain |
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