ES2914781T3 - Composiciones para el tratamiento de la amiloidosis - Google Patents

Composiciones para el tratamiento de la amiloidosis Download PDF

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Publication number
ES2914781T3
ES2914781T3 ES17740200T ES17740200T ES2914781T3 ES 2914781 T3 ES2914781 T3 ES 2914781T3 ES 17740200 T ES17740200 T ES 17740200T ES 17740200 T ES17740200 T ES 17740200T ES 2914781 T3 ES2914781 T3 ES 2914781T3
Authority
ES
Spain
Prior art keywords
antibody
patient
peripheral neuropathy
treatment
amyloidosis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES17740200T
Other languages
English (en)
Spanish (es)
Inventor
Gene G Kinney
Spencer D Guthrie
Martin Koller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Prothena Biosciences Ltd
Original Assignee
Prothena Biosciences Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Prothena Biosciences Ltd filed Critical Prothena Biosciences Ltd
Application granted granted Critical
Publication of ES2914781T3 publication Critical patent/ES2914781T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/569Single domain, e.g. dAb, sdAb, VHH, VNAR or nanobody®

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ES17740200T 2016-06-30 2017-06-30 Composiciones para el tratamiento de la amiloidosis Active ES2914781T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662357151P 2016-06-30 2016-06-30
PCT/US2017/040289 WO2018005967A1 (en) 2016-06-30 2017-06-30 Compositions for treating amyloidosis

Publications (1)

Publication Number Publication Date
ES2914781T3 true ES2914781T3 (es) 2022-06-16

Family

ID=59351103

Family Applications (1)

Application Number Title Priority Date Filing Date
ES17740200T Active ES2914781T3 (es) 2016-06-30 2017-06-30 Composiciones para el tratamiento de la amiloidosis

Country Status (16)

Country Link
US (2) US20190169280A1 (https=)
EP (1) EP3478713B1 (https=)
JP (3) JP2019519584A (https=)
CY (1) CY1125536T1 (https=)
DK (1) DK3478713T3 (https=)
ES (1) ES2914781T3 (https=)
HR (1) HRP20220979T8 (https=)
HU (1) HUE059400T2 (https=)
LT (1) LT3478713T (https=)
MA (1) MA45552A (https=)
PL (1) PL3478713T3 (https=)
PT (1) PT3478713T (https=)
RS (1) RS63446B1 (https=)
SI (1) SI3478713T1 (https=)
SM (1) SMT202200261T1 (https=)
WO (1) WO2018005967A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7217287B2 (ja) * 2018-03-23 2023-02-02 プロシーナ バイオサイエンシーズ リミテッド アミロイド症の処置および予防
JP2022520572A (ja) * 2019-02-12 2022-03-31 プロシーナ バイオサイエンシーズ リミテッド 免疫グロブリン軽鎖に対するモノクローナル抗体と、抗体産生細胞および他の免疫細胞上のcd38細胞膜分子に対するモノクローナル抗体の組み合わせによるalアミロイドーシスの処置
EP4582446A3 (en) * 2019-03-05 2025-08-13 Prothena Biosciences Limited Methods of treating al amyloidosis
EP4022062A1 (en) * 2019-08-30 2022-07-06 Alnylam Pharmaceuticals, Inc. Neurofilament light chain (nfl) as a biomarker for transthyretin amyloidosis polyneuropathy
CA3187944A1 (en) * 2020-06-22 2021-12-30 Ngm Biopharmaceuticals, Inc. Lair-1-binding agents and methods of use thereof
TW202332465A (zh) * 2021-01-29 2023-08-16 愛爾蘭商普羅希那生物科學有限公司 治療al類澱粉變性症之方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7083784B2 (en) 2000-12-12 2006-08-01 Medimmune, Inc. Molecules with extended half-lives, compositions and uses thereof
DK2237803T3 (en) 2007-12-28 2015-10-05 Prothena Biosciences Ltd Treatment and prophylaxis of amyloidosis
CN107233569B (zh) 2011-10-25 2021-08-31 普罗西纳生物科学有限公司 抗体制剂和方法

Also Published As

Publication number Publication date
EP3478713B1 (en) 2022-05-11
RS63446B1 (sr) 2022-08-31
SMT202200261T1 (it) 2022-07-21
HUE059400T2 (hu) 2022-11-28
PT3478713T (pt) 2022-05-27
US20210079078A1 (en) 2021-03-18
PL3478713T3 (pl) 2022-10-10
DK3478713T3 (da) 2022-06-20
US20190169280A1 (en) 2019-06-06
WO2018005967A1 (en) 2018-01-04
SI3478713T1 (sl) 2022-06-30
JP2024127990A (ja) 2024-09-20
HRP20220979T1 (hr) 2022-11-11
EP3478713A1 (en) 2019-05-08
JP2019519584A (ja) 2019-07-11
HRP20220979T8 (hr) 2023-02-03
CY1125536T1 (el) 2025-05-09
MA45552A (fr) 2019-05-08
LT3478713T (lt) 2022-06-10
JP2022121658A (ja) 2022-08-19

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