RS63446B1 - Kompozicije za lečenje amiloidoze - Google Patents

Kompozicije za lečenje amiloidoze

Info

Publication number
RS63446B1
RS63446B1 RS20220716A RSP20220716A RS63446B1 RS 63446 B1 RS63446 B1 RS 63446B1 RS 20220716 A RS20220716 A RS 20220716A RS P20220716 A RSP20220716 A RS P20220716A RS 63446 B1 RS63446 B1 RS 63446B1
Authority
RS
Serbia
Prior art keywords
antibody
patient
treatment
duration
patients
Prior art date
Application number
RS20220716A
Other languages
English (en)
Serbian (sr)
Inventor
Gene G Kinney
Spencer D Guthrie
Martin Koller
Original Assignee
Prothena Biosciences Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Prothena Biosciences Ltd filed Critical Prothena Biosciences Ltd
Publication of RS63446B1 publication Critical patent/RS63446B1/sr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/569Single domain, e.g. dAb, sdAb, VHH, VNAR or nanobody®

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
RS20220716A 2016-06-30 2017-06-30 Kompozicije za lečenje amiloidoze RS63446B1 (sr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662357151P 2016-06-30 2016-06-30
PCT/US2017/040289 WO2018005967A1 (en) 2016-06-30 2017-06-30 Compositions for treating amyloidosis
EP17740200.5A EP3478713B1 (en) 2016-06-30 2017-06-30 Compositions for treating amyloidosis

Publications (1)

Publication Number Publication Date
RS63446B1 true RS63446B1 (sr) 2022-08-31

Family

ID=59351103

Family Applications (1)

Application Number Title Priority Date Filing Date
RS20220716A RS63446B1 (sr) 2016-06-30 2017-06-30 Kompozicije za lečenje amiloidoze

Country Status (16)

Country Link
US (2) US20190169280A1 (https=)
EP (1) EP3478713B1 (https=)
JP (3) JP2019519584A (https=)
CY (1) CY1125536T1 (https=)
DK (1) DK3478713T3 (https=)
ES (1) ES2914781T3 (https=)
HR (1) HRP20220979T8 (https=)
HU (1) HUE059400T2 (https=)
LT (1) LT3478713T (https=)
MA (1) MA45552A (https=)
PL (1) PL3478713T3 (https=)
PT (1) PT3478713T (https=)
RS (1) RS63446B1 (https=)
SI (1) SI3478713T1 (https=)
SM (1) SMT202200261T1 (https=)
WO (1) WO2018005967A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7217287B2 (ja) * 2018-03-23 2023-02-02 プロシーナ バイオサイエンシーズ リミテッド アミロイド症の処置および予防
JP2022520572A (ja) * 2019-02-12 2022-03-31 プロシーナ バイオサイエンシーズ リミテッド 免疫グロブリン軽鎖に対するモノクローナル抗体と、抗体産生細胞および他の免疫細胞上のcd38細胞膜分子に対するモノクローナル抗体の組み合わせによるalアミロイドーシスの処置
EP4582446A3 (en) * 2019-03-05 2025-08-13 Prothena Biosciences Limited Methods of treating al amyloidosis
EP4022062A1 (en) * 2019-08-30 2022-07-06 Alnylam Pharmaceuticals, Inc. Neurofilament light chain (nfl) as a biomarker for transthyretin amyloidosis polyneuropathy
CA3187944A1 (en) * 2020-06-22 2021-12-30 Ngm Biopharmaceuticals, Inc. Lair-1-binding agents and methods of use thereof
TW202332465A (zh) * 2021-01-29 2023-08-16 愛爾蘭商普羅希那生物科學有限公司 治療al類澱粉變性症之方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7083784B2 (en) 2000-12-12 2006-08-01 Medimmune, Inc. Molecules with extended half-lives, compositions and uses thereof
DK2237803T3 (en) 2007-12-28 2015-10-05 Prothena Biosciences Ltd Treatment and prophylaxis of amyloidosis
CN107233569B (zh) 2011-10-25 2021-08-31 普罗西纳生物科学有限公司 抗体制剂和方法

Also Published As

Publication number Publication date
EP3478713B1 (en) 2022-05-11
SMT202200261T1 (it) 2022-07-21
HUE059400T2 (hu) 2022-11-28
PT3478713T (pt) 2022-05-27
US20210079078A1 (en) 2021-03-18
PL3478713T3 (pl) 2022-10-10
DK3478713T3 (da) 2022-06-20
ES2914781T3 (es) 2022-06-16
US20190169280A1 (en) 2019-06-06
WO2018005967A1 (en) 2018-01-04
SI3478713T1 (sl) 2022-06-30
JP2024127990A (ja) 2024-09-20
HRP20220979T1 (hr) 2022-11-11
EP3478713A1 (en) 2019-05-08
JP2019519584A (ja) 2019-07-11
HRP20220979T8 (hr) 2023-02-03
CY1125536T1 (el) 2025-05-09
MA45552A (fr) 2019-05-08
LT3478713T (lt) 2022-06-10
JP2022121658A (ja) 2022-08-19

Similar Documents

Publication Publication Date Title
RS63446B1 (sr) Kompozicije za lečenje amiloidoze
KR101320198B1 (ko) 신생물의 치료를 위한 조성물 및 방법
US20160031990A1 (en) Antagonists of pdl-1 and pd-1 for the treatment of hpv-negative cancers
JP7619953B2 (ja) Alアミロイドーシスを処置する方法
CN113316588A (zh) 用于治疗炎性小体相关疾病或病症的组合物和方法
US20250075007A1 (en) Treatment of Al Amyloidosis with the Combination of Monoclonal Antibodies Agains Immunoglobulin Light Chains and the CD38 Cell Membrane Molecule on Antibody-Producing And Other Immune Cells
AU2020341135A1 (en) Treatment of liver disease or disorder comprising ActRII receptor antagonists
JP7405764B2 (ja) C末端抗体改変体
JP2025530190A (ja) アルツハイマー病治療のための免疫療法薬とscyllo-イノシトールとの組み合わせ
Ashfaque et al. Suppression to removal, an emerging therapeutic approach for AL amyloidosis: A comprehensive review with early human data and pharmacokinetics of CAEL-101 antibody
US9486475B2 (en) PPS for the prevention of potential adverse effects caused by CD3 specific binding domains
KR20240133743A (ko) Al 아밀로이드증 치료 방법
KR20230136643A (ko) Al 아밀로이드증 치료 방법
HK40008815B (en) Compositions for treating amyloidosis
JP7217287B2 (ja) アミロイド症の処置および予防
WO2025170969A1 (en) Methods of treating al amyloidosis
TW202613167A (zh) 使用抗tl1a抗體治療發炎性腸病之方法
EA047876B1 (ru) Лечение al-амилоидоза комбинацией моноклональных антител против легких цепей иммуноглобулина и молекул клеточной мембраны cd38 в продуцирующих антитела и других иммунных клетках
HK40055003A (zh) 用於治疗炎性小体相关疾病或病症的组合物和方法
EA044759B1 (ru) Лечение и профилактика амилоидоза