ES2912291T3 - Elementos potenciadores de CPMV modificados - Google Patents

Elementos potenciadores de CPMV modificados Download PDF

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Publication number
ES2912291T3
ES2912291T3 ES15769248T ES15769248T ES2912291T3 ES 2912291 T3 ES2912291 T3 ES 2912291T3 ES 15769248 T ES15769248 T ES 15769248T ES 15769248 T ES15769248 T ES 15769248T ES 2912291 T3 ES2912291 T3 ES 2912291T3
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ES
Spain
Prior art keywords
sequence
plant
cpmv
seq
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES15769248T
Other languages
English (en)
Spanish (es)
Inventor
Marc-Andre D'aoust
Pierre-Olivier Lavoie
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medicago Inc
Original Assignee
Medicago Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/CA2014/050326 external-priority patent/WO2014153674A1/en
Application filed by Medicago Inc filed Critical Medicago Inc
Application granted granted Critical
Publication of ES2912291T3 publication Critical patent/ES2912291T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C07K14/08—RNA viruses
    • C07K14/11—Orthomyxoviridae, e.g. influenza virus

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Pulmonology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Communicable Diseases (AREA)
  • Cell Biology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Physiology (AREA)
ES15769248T 2014-03-27 2015-03-27 Elementos potenciadores de CPMV modificados Active ES2912291T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461971274P 2014-03-27 2014-03-27
PCT/CA2014/050326 WO2014153674A1 (en) 2013-03-28 2014-03-28 Influenza virus-like particle production in plants
PCT/CA2015/050240 WO2015143567A1 (en) 2014-03-27 2015-03-27 Modified cpmv enhancer elements

Publications (1)

Publication Number Publication Date
ES2912291T3 true ES2912291T3 (es) 2022-05-25

Family

ID=54193828

Family Applications (1)

Application Number Title Priority Date Filing Date
ES15769248T Active ES2912291T3 (es) 2014-03-27 2015-03-27 Elementos potenciadores de CPMV modificados

Country Status (8)

Country Link
US (1) US10563213B2 (enExample)
EP (1) EP3122883B1 (enExample)
JP (1) JP6599354B2 (enExample)
CN (1) CN106460005B (enExample)
AU (1) AU2015234595B2 (enExample)
CA (1) CA2943796C (enExample)
ES (1) ES2912291T3 (enExample)
WO (1) WO2015143567A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0800272D0 (en) 2008-01-08 2008-02-13 Plant Bioscience Ltd Protein expression systems
DK3092309T3 (da) * 2014-01-10 2021-04-12 Medicago Inc Cpmv-forstærkerelementer
WO2015143567A1 (en) 2014-03-27 2015-10-01 Medicago Inc. Modified cpmv enhancer elements
MX2020009495A (es) * 2018-03-14 2020-12-07 Medicago Inc Potenciador de la expresion en plantas.
MX2020013961A (es) * 2018-06-27 2021-03-09 Medicago Inc Mutantes de hemaglutinina del virus de la influenza.
JP7512546B2 (ja) * 2019-03-14 2024-07-09 アラミス バイオテクノロジーズ インコーポレイテッド 内因性植物発現エンハンサー
JP2024514875A (ja) * 2021-04-15 2024-04-03 バイオーケストラ カンパニー， リミテッド タンパク質発現を増強できるポリヌクレオチド及びその使用

Family Cites Families (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5428147A (en) 1983-04-15 1995-06-27 Mycogen Plant Science, Inc. Octopine T-DNA promoters
CA1280081C (en) 1984-09-24 1991-02-12 Calgene, Inc. Plant cell microinjection technique
US4945050A (en) 1984-11-13 1990-07-31 Cornell Research Foundation, Inc. Method for transporting substances into living cells and tissues and apparatus therefor
US5100792A (en) 1984-11-13 1992-03-31 Cornell Research Foundation, Inc. Method for transporting substances into living cells and tissues
US5036006A (en) 1984-11-13 1991-07-30 Cornell Research Foundation, Inc. Method for transporting substances into living cells and tissues and apparatus therefor
AU7360087A (en) 1986-04-30 1987-11-24 Boyce Thompson Institute For Plant Research Inc. Electric field mediated dna transformation of plant cells and organelles
US4962028A (en) 1986-07-09 1990-10-09 Dna Plant Technology Corporation Plant promotors
US4692028A (en) 1986-08-19 1987-09-08 Crafco, Inc. Sealant melter/applicator with automatic load switching system
DE3887375T2 (de) 1987-05-05 1994-06-09 Sandoz Ag Pflanzengewebe-Transformation.
EP0331083A3 (de) 1988-03-02 1990-11-28 Schweizerische Eidgenossenschaft Eidgenössische Technische Hochschule (Eth) Verfahren zur Herstellung transgener Pflanzen
US6403865B1 (en) 1990-08-24 2002-06-11 Syngenta Investment Corp. Method of producing transgenic maize using direct transformation of commercially important genotypes
ES2147551T3 (es) 1990-11-23 2000-09-16 Aventis Cropscience Nv Procedimiento para transformar plantas monocotiledoneas.
UA48104C2 (uk) 1991-10-04 2002-08-15 Новартіс Аг Фрагмент днк, який містить послідовність,що кодує інсектицидний протеїн, оптимізовану для кукурудзи,фрагмент днк, який забезпечує направлену бажану для серцевини стебла експресію зв'язаного з нею структурного гена в рослині, фрагмент днк, який забезпечує специфічну для пилку експресію зв`язаного з нею структурного гена в рослині, рекомбінантна молекула днк, спосіб одержання оптимізованої для кукурудзи кодуючої послідовності інсектицидного протеїну, спосіб захисту рослин кукурудзи щонайменше від однієї комахи-шкідника
WO1994000583A1 (en) 1992-06-23 1994-01-06 South Dakota State University Transformation of plants by direct injection of dna
EP1141356A2 (en) 1998-12-23 2001-10-10 The Samuel Roberts Noble Foundation, Inc. Plant transformation process
NZ513993A (en) 1999-04-21 2001-09-28 Samuel Roberts Noble Found Inc Plant transformation process
US7125978B1 (en) 1999-10-04 2006-10-24 Medicago Inc. Promoter for regulating expression of foreign genes
EP2287185A3 (en) * 1999-12-06 2012-10-10 Board Of Trustees Of The University Of Illinois High affinity TCR proteins and methods
DE10109354A1 (de) 2001-02-27 2002-09-05 Icon Genetics Ag Rekombinante virale Schaltersysteme
US8080255B2 (en) 2003-07-11 2011-12-20 Novavax Inc. Functional influenza virus like particles (VLPs)
SI1937301T1 (sl) 2005-10-18 2015-08-31 Novavax, Inc. Funkcionalni influenčnemu virusu podobni delci (VLP)
AU2007224034B2 (en) 2006-03-07 2012-03-29 Vaxinnate Corporation Compositions that include hemagglutinin, methods of making and methods of use thereof
US7618815B2 (en) 2006-03-08 2009-11-17 University Of Kentucky Research Foundation Viral vectors useful in soybean and methods of use
EP2029755A1 (en) 2006-05-22 2009-03-04 Plant Bioscience Limited Bipartite system, method and composition for the constitutive and inducible expression of high levels of foreign proteins in plants
US8697088B2 (en) 2007-05-25 2014-04-15 Novavax, Inc. VLPs derived from cells that do not express a viral matrix or core protein
CA2615372A1 (en) 2007-07-13 2009-01-13 Marc-Andre D'aoust Influenza virus-like particles (vlps) comprising hemagglutinin
AU2009202819B2 (en) 2007-07-13 2014-08-28 Aramis Biotechnologies Inc. Recombinant influenza virus-like particles (VLPs) produced in transgenic plants expressing hemagglutinin
GB0800272D0 (en) 2008-01-08 2008-02-13 Plant Bioscience Ltd Protein expression systems
EA034733B1 (ru) 2008-01-21 2020-03-13 Медикаго Инк. Нуклеиновая кислота для увеличенной экспрессии гемагглютинина вируса гриппа в растении и ее применение
EP2454229B1 (en) 2009-05-06 2017-09-13 Risen (Shanghai) Pharma Tech Co, Ltd. Amino acid derivatives for the treatment of neuropathic pain
CN102482328B (zh) 2009-06-24 2014-11-26 麦迪卡格公司 包含血凝素的嵌合流感病毒样颗粒
KR20120093193A (ko) * 2009-09-04 2012-08-22 신젠타 파티서페이션즈 아게 식물 폴리펩티드 발현 증가를 위한 번역 향상제 요소의 적층
US20130295609A1 (en) * 2010-11-04 2013-11-07 Medicago Inc. Plant expression system
TWI526539B (zh) 2010-12-22 2016-03-21 苜蓿股份有限公司 植物中生產類病毒顆粒(vlp)的方法及以該方法生產之vlp
TWI620816B (zh) 2011-03-23 2018-04-11 苜蓿股份有限公司 植物衍生蛋白回收方法
US20140227322A1 (en) 2011-06-13 2014-08-14 Medicago Inc. Rabies virus like particle production in plants
PL220281B1 (pl) 2011-09-23 2015-09-30 Inst Biochemii I Biofizyki Polskiej Akademii Nauk Szczepionka DNA, sposób indukowania odpowiedzi immunologicznej, przeciwciała specyficznie rozpoznające białko hemaglutyniny H5 wirusa grypy i zastosowanie szczepionki DNA
CA2850407C (en) * 2011-09-30 2021-11-23 Medicago Inc. Increasing virus-like particle yield in plants
CA2855252C (en) 2011-11-11 2023-03-07 Philip Morris Products S.A. Influenza virus-like particles (vlps) comprising hemagglutinin produced in nicotiana tabacum
JP2016516415A (ja) 2013-03-28 2016-06-09 メディカゴ インコーポレイテッド 植物におけるインフルエンザウイルス様粒子の生成
WO2015143567A1 (en) 2014-03-27 2015-10-01 Medicago Inc. Modified cpmv enhancer elements

Also Published As

Publication number Publication date
WO2015143567A1 (en) 2015-10-01
JP2017513467A (ja) 2017-06-01
AU2015234595A1 (en) 2016-10-13
CN106460005A (zh) 2017-02-22
AU2015234595B2 (en) 2021-03-25
CA2943796A1 (en) 2015-10-01
US20180119158A1 (en) 2018-05-03
US10563213B2 (en) 2020-02-18
JP6599354B2 (ja) 2019-10-30
EP3122883A4 (en) 2017-11-29
EP3122883A1 (en) 2017-02-01
EP3122883B1 (en) 2022-03-02
CA2943796C (en) 2023-02-14
CN106460005B (zh) 2020-01-03

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