ES2906449T3 - Sensor electroquímico que tiene áreas sensibles a analito distribuidas simétricamente - Google Patents
Sensor electroquímico que tiene áreas sensibles a analito distribuidas simétricamente Download PDFInfo
- Publication number
- ES2906449T3 ES2906449T3 ES11769782T ES11769782T ES2906449T3 ES 2906449 T3 ES2906449 T3 ES 2906449T3 ES 11769782 T ES11769782 T ES 11769782T ES 11769782 T ES11769782 T ES 11769782T ES 2906449 T3 ES2906449 T3 ES 2906449T3
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/1468—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means
- A61B5/1473—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means invasive, e.g. introduced into the body by a catheter
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/1468—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/1468—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means
- A61B5/1477—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means non-invasive
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/14503—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/14507—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue specially adapted for measuring characteristics of body fluids other than blood
- A61B5/1451—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/1468—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means
- A61B5/1486—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
- A61B5/14865—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B5/2415—Measuring direct current [DC] or slowly varying biopotentials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B5/25—Bioelectric electrodes therefor
- A61B5/263—Bioelectric electrodes therefor characterised by the electrode materials
- A61B5/265—Bioelectric electrodes therefor characterised by the electrode materials containing silver or silver chloride
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/28—Electrolytic cell components
- G01N27/30—Electrodes, e.g. test electrodes; Half-cells
- G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/28—Electrolytic cell components
- G01N27/30—Electrodes, e.g. test electrodes; Half-cells
- G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
- G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2560/00—Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
- A61B2560/04—Constructional details of apparatus
- A61B2560/0462—Apparatus with built-in sensors
- A61B2560/0468—Built-in electrodes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
- A61B2562/04—Arrangements of multiple sensors of the same type
- A61B2562/043—Arrangements of multiple sensors of the same type in a linear array
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/28—Electrolytic cell components
- G01N27/30—Electrodes, e.g. test electrodes; Half-cells
- G01N27/301—Reference electrodes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Pathology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Biomedical Technology (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Optics & Photonics (AREA)
- General Chemical & Material Sciences (AREA)
- Electrochemistry (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12/901,078 US9084570B2 (en) | 2010-10-08 | 2010-10-08 | Electrochemical sensor having symmetrically distributed analyte sensitive areas |
| PCT/EP2011/004913 WO2012045425A1 (en) | 2010-10-08 | 2011-10-01 | Electrochemical sensor having symmetrically distributed analyte sensitive areas |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2906449T3 true ES2906449T3 (es) | 2022-04-18 |
Family
ID=44799976
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES11769782T Active ES2906449T3 (es) | 2010-10-08 | 2011-10-01 | Sensor electroquímico que tiene áreas sensibles a analito distribuidas simétricamente |
| ES21180905T Active ES2983452T3 (es) | 2010-10-08 | 2011-10-01 | Sensor electroquímico que tiene áreas sensibles a analito distribuidas simétricamente |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES21180905T Active ES2983452T3 (es) | 2010-10-08 | 2011-10-01 | Sensor electroquímico que tiene áreas sensibles a analito distribuidas simétricamente |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US9084570B2 (cg-RX-API-DMAC7.html) |
| EP (2) | EP2624756B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP6104805B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR20130057477A (cg-RX-API-DMAC7.html) |
| CN (1) | CN103140170B (cg-RX-API-DMAC7.html) |
| AU (1) | AU2011313631A1 (cg-RX-API-DMAC7.html) |
| ES (2) | ES2906449T3 (cg-RX-API-DMAC7.html) |
| HU (2) | HUE057419T2 (cg-RX-API-DMAC7.html) |
| MX (1) | MX2013003471A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2012045425A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010033724A2 (en) | 2008-09-19 | 2010-03-25 | Dexcom, Inc. | Particle-containing membrane and particulate electrode for analyte sensors |
| US9084570B2 (en) * | 2010-10-08 | 2015-07-21 | Roche Diagnostics Operations, Inc. | Electrochemical sensor having symmetrically distributed analyte sensitive areas |
| EP2649191B1 (en) * | 2010-12-09 | 2021-06-16 | Abbott Diabetes Care, Inc. | Analyte sensors with a sensing surface having small sensing spots |
| US9535027B2 (en) | 2012-07-25 | 2017-01-03 | Abbott Diabetes Care Inc. | Analyte sensors and methods of using same |
| CN104055526A (zh) * | 2013-12-05 | 2014-09-24 | 庞德兴 | 一种无源微创皮下生化参数检测芯片 |
| JP6526193B2 (ja) * | 2014-11-03 | 2019-06-05 | エフ ホフマン−ラ ロッシュ アクチェン ゲゼルシャフト | 電気化学的テストエレメントのための電極配置およびその使用方法 |
| EP4191239A1 (en) * | 2014-12-19 | 2023-06-07 | Roche Diagnostics GmbH | Test element for electrochemically detecting at least one analyte |
| EP3170451A1 (en) * | 2015-11-19 | 2017-05-24 | Roche Diabetes Care GmbH | Sensor and sensor assembly for detecting an analyte in a body fluid |
| PL3558116T3 (pl) * | 2016-12-22 | 2022-01-03 | Sanvita Medical, Llc | System i sposób ciągłego monitorowania poziomu glukozy |
| WO2018229581A1 (en) | 2017-06-11 | 2018-12-20 | Kenzen Ag | Chip-based multi-channel electrochemical transducer and method of use thereof |
| EP3457121B1 (en) * | 2017-09-18 | 2025-03-12 | Roche Diabetes Care GmbH | Electrochemical sensor for detecting at least one analyte |
| SI3482687T1 (sl) * | 2017-11-08 | 2021-01-29 | Roche Diabetes Care Gmbh | Senzor za zaznavanje analita v telesni tekočini in postopek njegove izdelave |
| US12076145B2 (en) | 2018-04-19 | 2024-09-03 | Abbott Diabetes Care Inc. | Lactate sensors and associated methods |
| CN109959679B (zh) * | 2019-03-08 | 2020-06-05 | 浙江大学 | 一种用于3d肿瘤细胞迁移实时监测的垂直多电极阻抗传感器及制备方法 |
| JP7264465B2 (ja) * | 2019-06-24 | 2023-04-25 | テクノグローバル株式会社 | 電極構造体、電気化学測定装置、及び電気化学測定方法 |
| EP3798628B1 (en) * | 2019-09-27 | 2025-04-16 | Heraeus Medevio GmbH & Co. KG | Method for manufacturing an electrochemical sensor |
| KR102296827B1 (ko) | 2019-11-08 | 2021-09-01 | 재단법인대구경북과학기술원 | 삽입형 바이오센서 |
| US20230003679A1 (en) * | 2019-12-06 | 2023-01-05 | Innovative Water Care, Llc | Amperometric sensor for measuring free chlorine with reference electrode having a gold electrode surface composed of a string of electrically connected, spaced apart surface parts |
| US11877847B2 (en) * | 2020-01-31 | 2024-01-23 | Taiwan Semiconductor Manufacturing Company, Ltd. | Biosensor apparatus |
| KR102346784B1 (ko) * | 2020-08-06 | 2022-01-04 | 알사란 자빕 | 생화학 키트 및 이를 이용한 생화학 정보 측정방법 |
| CN116897015A (zh) * | 2020-12-23 | 2023-10-17 | 雅培糖尿病护理公司 | 具有减少的干扰物信号的分析物传感器和方法 |
| EP4085829A1 (en) | 2021-05-06 | 2022-11-09 | Roche Diabetes Care GmbH | Analyte sensor and a method for its producing |
| CN113740400B (zh) * | 2021-08-18 | 2023-10-24 | 淮阴工学院 | 带有对称参比电极的封闭式双极电极阵列的分析检测装置 |
| ES3010357T3 (en) | 2021-08-18 | 2025-04-02 | Hoffmann La Roche | Analyte sensor and a method for its producing |
| CN114184661B (zh) * | 2021-11-26 | 2025-03-14 | 北京大学 | 一种电化学传感器及其制造方法 |
| US20240108257A1 (en) * | 2022-03-11 | 2024-04-04 | Integrated Medical Sensors, Inc. | Wired implantable multianalyte monolithic integrated sensor circuit |
| US20230389837A1 (en) * | 2022-05-05 | 2023-12-07 | Cercacor Laboratories, Inc. | Analyte sensor for measuring at varying depths within a user |
| GB202218073D0 (en) * | 2022-12-01 | 2023-01-18 | Freeman Neville | Electrochemical electrode assembly |
| WO2025178614A1 (en) * | 2024-02-21 | 2025-08-28 | Roche Diabetes Care, Inc. | Continuous analyte monitor |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4655880A (en) | 1983-08-01 | 1987-04-07 | Case Western Reserve University | Apparatus and method for sensing species, substances and substrates using oxidase |
| US5711861A (en) * | 1995-11-22 | 1998-01-27 | Ward; W. Kenneth | Device for monitoring changes in analyte concentration |
| US6139718A (en) | 1997-03-25 | 2000-10-31 | Cygnus, Inc. | Electrode with improved signal to noise ratio |
| KR100349000B1 (ko) | 1998-07-09 | 2003-03-26 | 주식회사 아이센스 | 친수성폴리우레탄을사용한바이오센서의제조방법 |
| US6501976B1 (en) * | 2001-06-12 | 2002-12-31 | Lifescan, Inc. | Percutaneous biological fluid sampling and analyte measurement devices and methods |
| US7813780B2 (en) * | 2005-12-13 | 2010-10-12 | Medtronic Minimed, Inc. | Biosensors and methods for making and using them |
| US7467003B2 (en) | 2003-12-05 | 2008-12-16 | Dexcom, Inc. | Dual electrode system for a continuous analyte sensor |
| US8060174B2 (en) * | 2005-04-15 | 2011-11-15 | Dexcom, Inc. | Analyte sensing biointerface |
| US7985330B2 (en) | 2005-12-30 | 2011-07-26 | Medtronic Minimed, Inc. | Method and system for detecting age, hydration, and functional states of sensors using electrochemical impedance spectroscopy |
| US20070173712A1 (en) | 2005-12-30 | 2007-07-26 | Medtronic Minimed, Inc. | Method of and system for stabilization of sensors |
| US7826879B2 (en) | 2006-02-28 | 2010-11-02 | Abbott Diabetes Care Inc. | Analyte sensors and methods of use |
| US7653425B2 (en) | 2006-08-09 | 2010-01-26 | Abbott Diabetes Care Inc. | Method and system for providing calibration of an analyte sensor in an analyte monitoring system |
| US20070299617A1 (en) | 2006-06-27 | 2007-12-27 | Willis John P | Biofouling self-compensating biosensor |
| US7751864B2 (en) | 2007-03-01 | 2010-07-06 | Roche Diagnostics Operations, Inc. | System and method for operating an electrochemical analyte sensor |
| EP1987761B1 (de) * | 2007-05-03 | 2019-10-23 | F. Hoffmann-La Roche AG | Schlauchförmiger Sensor zum Nachweis eines Analyten |
| EP2535704B1 (en) * | 2007-09-24 | 2015-09-09 | Bayer HealthCare LLC | Multi-electrode test method |
| DE102008005065A1 (de) * | 2008-01-18 | 2009-07-30 | Cellasys Gmbh | Referenzelektrode |
| WO2009097357A1 (en) | 2008-01-29 | 2009-08-06 | Medtronic Minimed, Inc. | Analyte sensors having nanostructured electrodes and methods for making and using them |
| US8396528B2 (en) | 2008-03-25 | 2013-03-12 | Dexcom, Inc. | Analyte sensor |
| US20100025238A1 (en) | 2008-07-31 | 2010-02-04 | Medtronic Minimed, Inc. | Analyte sensor apparatuses having improved electrode configurations and methods for making and using them |
| EP2163190A1 (de) | 2008-09-11 | 2010-03-17 | Roche Diagnostics GmbH | Elektrodensystem für Messung einer Analytkonzentration in-vivo |
| US8986208B2 (en) | 2008-09-30 | 2015-03-24 | Abbott Diabetes Care Inc. | Analyte sensor sensitivity attenuation mitigation |
| US9084570B2 (en) * | 2010-10-08 | 2015-07-21 | Roche Diagnostics Operations, Inc. | Electrochemical sensor having symmetrically distributed analyte sensitive areas |
| US9357958B2 (en) | 2012-06-08 | 2016-06-07 | Medtronic Minimed, Inc. | Application of electrochemical impedance spectroscopy in sensor systems, devices, and related methods |
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| HUE067577T2 (hu) | 2024-10-28 |
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| EP3926339C0 (en) | 2024-05-15 |
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| CN103140170A (zh) | 2013-06-05 |
| HUE057419T2 (hu) | 2022-05-28 |
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| US9757060B2 (en) | 2017-09-12 |
| EP3926339B1 (en) | 2024-05-15 |
| US20170367628A1 (en) | 2017-12-28 |
| EP3926339A1 (en) | 2021-12-22 |
| US10349878B2 (en) | 2019-07-16 |
| US9084570B2 (en) | 2015-07-21 |
| JP2013543405A (ja) | 2013-12-05 |
| HK1185780A1 (zh) | 2014-02-28 |
| EP2624756A1 (en) | 2013-08-14 |
| JP6104805B2 (ja) | 2017-03-29 |
| KR20130057477A (ko) | 2013-05-31 |
| WO2012045425A1 (en) | 2012-04-12 |
| US20150320345A1 (en) | 2015-11-12 |
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